Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Note: This description may include information from UniProtKB.
Protein type: Ligand, receptor tyrosine kinase; Cell cycle regulation; Membrane protein, integral
Cellular Component: extracellular space; integral to membrane; extracellular region; plasma membrane
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.