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Protein Page:
FLT3LG (human)

FLT3LG Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Membrane protein, integral; Ligand, receptor tyrosine kinase
Chromosomal Location of Human Ortholog: 19q13.3
Cellular Component: extracellular space; membrane; integral to membrane
Molecular Function: protein homodimerization activity; cytokine activity; receptor tyrosine kinase binding; receptor binding
Biological Process: regulation of myeloid dendritic cell activation; positive regulation of natural killer cell differentiation; lymphocyte differentiation; embryonic hemopoiesis; positive regulation of cell proliferation; positive regulation of protein amino acid phosphorylation; signal transduction; positive regulation of myoblast differentiation
Reference #:  P49771 (UniProtKB)
Gene Symbols: FLT3LG
Molecular weight: 26,416 Da
Basal Isoelectric point: 7.6  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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