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LEFTY1
Required for left-right axis determination as a regulator of LEFTY2 and NODAL. Belongs to the TGF-beta family. Note: This description may include information from UniProtKB.
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| Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Cytokine; Ligand, receptor tyrosine kinase; Secreted |
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Cellular Component: extracellular space
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Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding
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Biological Process: heart morphogenesis; transforming growth factor beta receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; cell growth; determination of left/right symmetry
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Reference #:
O75610 (UniProtKB)
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| Alt. Names/Synonyms: BMP-17; BMP17; lefty b; lefty-1; lefty-b; lefty1; leftyb; stra3 |
| Gene Symbols: LEFTY1 |
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Molecular weight: 40,880 Da
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Basal Isoelectric point: 8.6
Predict pI for various phosphorylation states
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Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®
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