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Protein Page:
LEFTY1 (human)

LEFTY1 Required for left-right axis determination as a regulator of LEFTY2 and NODAL. Belongs to the TGF-beta family. Note: This description may include information from UniProtKB.
Protein type: Ligand, receptor tyrosine kinase; Cytokine; Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1q42.1
Cellular Component: extracellular space
Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding
Biological Process: regulation of apoptosis; heart morphogenesis; transforming growth factor beta receptor signaling pathway; regulation of MAPKKK cascade; negative regulation of transcription from RNA polymerase II promoter; cell growth; determination of left/right symmetry; cell development
Reference #:  O75610 (UniProtKB)
Alt. Names/Synonyms: BMP-17; BMP17; lefty b; lefty-1; lefty-b; lefty1; leftyb; stra3
Gene Symbols: LEFTY1
Molecular weight: 40,880 Da
Basal Isoelectric point: 8.6  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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