|
IL7
Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
|
| Protein type: Secreted; Cell development/differentiation; Cell cycle regulation; Apoptosis; Cytokine; Secreted, signal peptide |
|
Cellular Component: extracellular space; extracellular region
|
|
Molecular Function: interleukin-7 receptor binding; protein binding; growth factor activity; cytokine activity
|
|
Biological Process: positive regulation of organ growth; humoral immune response; organ morphogenesis; T cell lineage commitment; cell-cell signaling; positive regulation of T cell differentiation; regulation of gene expression; homeostasis of number of cells within a tissue; negative regulation of catalytic activity; positive regulation of cell proliferation; positive regulation of B cell proliferation; negative regulation of cell growth; negative regulation of apoptosis; bone resorption
|
|
Reference #:
P13232 (UniProtKB)
|
| Gene Symbols: IL7 |
|
Molecular weight: 20,187 Da
|
|
Basal Isoelectric point: 8.87
Predict pI for various phosphorylation states
|
