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Protein Page:
IL7 (human)

IL7 Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Secreted, signal peptide; Secreted; Cell development/differentiation; Cell cycle regulation; Cytokine; Apoptosis
Chromosomal Location of Human Ortholog: 8q12-q13
Cellular Component: extracellular space; extracellular region
Molecular Function: interleukin-7 receptor binding; protein binding; growth factor activity; cytokine activity
Biological Process: positive regulation of organ growth; humoral immune response; organ morphogenesis; T cell lineage commitment; cell-cell signaling; positive regulation of T cell differentiation; homeostasis of number of cells within a tissue; regulation of gene expression; negative regulation of catalytic activity; positive regulation of cell proliferation; positive regulation of B cell proliferation; bone resorption; negative regulation of apoptosis
Reference #:  P13232 (UniProtKB)
Gene Symbols: IL7
Molecular weight: 20,187 Da
Basal Isoelectric point: 8.87  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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