Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
eIF4G iso3 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
eIF4G iso3 Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. Interacts with eIF3, mutually exclusive with EIF4A1 or EIFA2, EIF4E and through its N-terminus with PAPBC1. Interacts through its C-terminus with the serine/threonine kinases MKNK1, and with MKNK2. Appears to act as a scaffold protein, holding these enzymes in place to phosphorylate EIF4E. Non-phosphorylated EIF4EBP1 competes with EIF4G1/EIF4G3 to interact with EIF4E; insulin stimulated MAP-kinase (MAPK1 and MAPK3) phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. EIF4G1/EIF4G3 interacts with PABPC1 to bring about circularization of the mRNA. Rapamycin can attenuate insulin stimulation mediated by FKBPs. Interacts with EIF4E3. Interacts with CIRBP and MIF4GD. Interacts with rotavirus A NSP3; in this interaction, NSP3 takes the place of PABPC1 thereby inducing shutoff of host protein synthesis. Interacts with RBM4. Belongs to the eIF4G family. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Translation initiation; Translation
Cellular Component: eukaryotic translation initiation factor 4F complex; cytosol
Molecular Function: protein binding; translation factor activity, nucleic acid binding; translation initiation factor activity
Biological Process: cell death; translation; viral reproduction; cytokine and chemokine mediated signaling pathway; mRNA metabolic process; poly(A) tail shortening; cellular protein metabolic process; RNA metabolic process; translational initiation; insulin receptor signaling pathway; mRNA catabolic process, nonsense-mediated decay; gene expression; mRNA catabolic process, deadenylation-dependent decay; regulation of translational initiation
Reference #:  Q04637-3 (UniProtKB)
Alt. Names/Synonyms: DKFZp686A1451; eIF-4-gamma 1; eIF-4G 1; eIF-4G1; EIF4-gamma; EIF4F; EIF4G; EIF4G1; EIF4GI; Eukaryotic translation initiation factor 4 gamma 1; eukaryotic translation initiation factor 4 gamma, 1; IF4G1; p220
Gene Symbols: EIF4G1
Molecular weight: 171,514 Da
Basal Isoelectric point: 5.23  Predict pI for various phosphorylation states
CST Pathways:  Translation: eIF4E and p70S6K  |  Translational Control
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

eIF4G iso3

Protein Structure Not Found.


Scansite  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 1 S15 TGPPPAPSPGLPQPA
0 4 R48-m2 MNTPSQPrQHFyPSr
0 1 Y52-p SQPrQHFyPSrAQPP
0 5 R55-m1 rQHFyPSrAQPPSsA
0 3 R55-m2 rQHFyPSrAQPPSsA
0 1 S61-gl SrAQPPSsAASrVQS
0 1 R65-m1 PPSsAASrVQSAAPA
0 1 R73-m1 VQSAAPArPGPAAHV
0 15 Y103-p YPASQGAyYIPGQGr
0 7 R110-m1 yYIPGQGrSTYVVPT
0 1 T179-p APKRERKtIRIRDPN
0 1 K190-ac RDPNQGGkDITEEIM
0 1 K190 RDPNQGGKDITEEIM
1 5 T202-p EIMSGARtAstPtPP
0 6 S204-p MSGARtAstPtPPQt
1 26 T205-p SGARtAstPtPPQtG
1 20 T207-p ARtAstPtPPQtGGG
1 10 T211-p stPtPPQtGGGLEPQ
0 2 G214 tPPQtGGGLEPQANG
0 7 T223-p EPQANGEtPQVAVIV
0 5 T301-p QMSVEEStPISRETG
0 6 Y311-p SRETGEPyRLsPEPt
0 12 S314-p TGEPyRLsPEPtPLA
0 1 T318-p yRLsPEPtPLAEPIL
0 1 S343-p PESEFSSsPLQAPtP
0 1 T349-p SsPLQAPtPLAsHTV
0 1 S353-p QAPtPLAsHTVEIHE
0 1 K524 KIKELNKKEAVGDLL
0 1 S561 PGPESEGSGVPPRPE
0 1 K580-ub TWDSKEDkIHNAENI
0 1 K593 NIQPGEQKyEYksDQ
0 4 K593-ub NIQPGEQkyEYksDQ
0 29 Y594-p IQPGEQkyEYksDQW
0 3 K597-ub GEQkyEYksDQWkPL
0 1 S598-p EQkyEYksDQWkPLN
0 6 K602-ub EYksDQWkPLNLEEk
0 1 K609-ub kPLNLEEkKRYDREF
2 9 T647-p VLDKANKtPLRPLDP
0 13 T667-p INCGPDFtPsFANLG
0 1 S669-p CGPDFtPsFANLGrT
0 5 R675-m1 PsFANLGrTTLSTrG
0 2 R681-m1 GrTTLSTrGPPrGGP
0 31 R685-m1 LSTrGPPrGGPGGEL
0 1 R694-m1 GPGGELPrGPAGLGP
0 1 R702-m1 GPAGLGPrRsQQGPR
1 7 S704-p AGLGPrRsQQGPRKE
0 1 T722 IIATVLMTEDIKLNK
0 3 K770-ub RVRSILNkLTPQMFQ
0 1 K781-ub QMFQQLMkQVTQLAI
0 1 T790 VTQLAIDTEERLkGV
0 2 K795-ub IDTEERLkGVIDLIF
0 7 K832-ub LKVPTTEkPTVTVNF
0 1 K863-ub DDDEVFEkKQKEMDE
0 3 K881-ub AEERGRLkEELEEAR
1 0 S895-p RDIARRRsLGNIkFI
0 2 K900-ub RRsLGNIkFIGELFK
0 3 K925-ub DCVVKLLkNHDEESL
0 2 K944-ub RLLTTIGkDLDFEkA
0 2 K950-ub GkDLDFEkAKPRMDQ
0 1 K964-ac QYFNQMEkIIkEKKT
0 1 K964-ub QYFNQMEkIIkEKKT
0 1 K967-ub NQMEkIIkEKKTSSR
0 3 S1028-p QQLMAKGsDKRrGGP
0 7 R1032-m1 AKGsDKRrGGPPGPP
0 7 R1042-m1 PPGPPISrGLPLVDD
0 10 T1054-p VDDGGWNtVPISkGS
0 2 K1059-ub WNtVPISkGSRPIDt
0 6 T1066-p kGSRPIDtSRLTKIt
1 0 T1073-p tSRLTKItKPGsIDs
0 1 K1074 SRLTKItKPGsIDsN
1 12 S1077-p TKItKPGsIDsNNQL
2 4 S1080-p tKPGsIDsNNQLFAP
2 23 S1092-p FAPGGRLsWGkGssG
0 1 K1095-ac GGRLsWGkGssGGsG
0 1 S1097-p RLsWGkGssGGsGAK
0 1 S1098-p LsWGkGssGGsGAKP
0 1 S1101-p GkGssGGsGAKPsDA
2 1 S1106-p GGsGAKPsDAAsEAA
0 2 S1110-p AKPsDAAsEAARPAT
1 0 T1119-p AARPATStLNRFSAL
0 1 S1124 TStLNRFSALQQAVP
0 1 A1129 RFSALQQAVPTESTD
0 1 T1135 QAVPTESTDNRRVVQ
1 1 S1144-p NRRVVQRssLsRERG
2 9 S1145-p RRVVQRssLsRERGE
15 14 S1147-p VVQRssLsRERGEKA
0 13 T1179-p DRLDRARtPATKRsF
0 2 T1182 DRARtPATKRsFskE
3 160 S1185-p RtPATKRsFskEVEE
3 49 S1187-p PATKRsFskEVEERs
0 1 K1188-ac ATKRsFskEVEERsR
1 9 S1194-p skEVEERsRERPSQP
1 37 S1209-p EGLRKAAsLtEDRDR
0 11 T1211-p LRKAAsLtEDRDRGR
0 3 A1226 DAVKREAALPPVsPL
4 96 S1231-p EAALPPVsPLKAALs
2 8 S1238-p sPLKAALsEEELEKK
0 1 Y1253-p SKAIIEEyLHLNDMK
0 1 K1404-ub REAGLSWkEFLPEGQ
0 1 Y1424-p VAEQKVEytLGEEsE
0 1 T1425-p AEQKVEytLGEEsEA
0 1 S1430-p EytLGEEsEAPGQRA
0 1 K1452 RQLEKLLKEGSSNQR
0 1 T1477 EQQIVSNTLVRALMT
0 1 Y1526-p QKELQALyALQALVV
0 1 T1534-p ALQALVVtLEQPPNL
0 1 Y1550-p RMFFDALyDEDVVKE
0 1 K1580-ub QGKGVALkSVTAFFK
1 24 S1596-p LREAEEEsDHN____
2441 : Phospho-eIF4G (Ser1108) Antibody
  eIF4G iso3  
- gap
R8 MNTPSQPRQHFYPSR
Y12 SQPRQHFYPSRAQPP
R15 RQHFYPSRAQPPSSA
R15 RQHFYPSRAQPPSSA
S21 SRAQPPSSAASRVQS
R25 PPSSAASRVQSAAPA
R33 VQSAAPARPGPAAHV
Y63 YPASQGAYYIPGQGR
R70 YYIPGQGRSTYVVPT
T139 APKRERKTIRIRDPN
K150 RDPNQGGKDITEEIM
K150 RDPNQGGKDITEEIM
T162 EIMSGARTAStPtPP
S164 MSGARTAStPtPPQT
T165-p SGARTAStPtPPQTG
T167-p ARTAStPtPPQTGGG
T171 StPtPPQTGGGLEPQ
G174 tPPQTGGGLEPQANG
T183 EPQANGETPQVAVIV
T261 QMSVEESTPISRETG
Y271 SRETGEPYRLSPEPT
S274 TGEPYRLSPEPTPLA
T278 YRLSPEPTPLAEPIL
S303 PESEFSSSPLQAPTP
T309 SSPLQAPTPLASHTV
S313 QAPTPLASHTVEIHE
K484 KIKELNKKEAVGDLL
S521 PGPESEGSGVPPRPE
K540 TWDSKEDKIHNAENI
K553 NIQPGEQKyEYKSDQ
K553 NIQPGEQKyEYKSDQ
Y554-p IQPGEQKyEYKSDQW
K557 GEQKyEYKSDQWKPL
S558 EQKyEYKSDQWKPLN
K562 EYKSDQWKPLNLEEK
K569 KPLNLEEKKRYDREF
T607 VLDKANKTPLRPLDP
T627 INCGPDFTPSFANLG
S629 CGPDFTPSFANLGRT
R635 PSFANLGRTTLSTRG
R641 GRTTLSTRGPPRGGP
R645 LSTRGPPRGGPGGEL
R654 GPGGELPRGPAGLGP
R663 PAGLGPRRSQQGPRK
S664 AGLGPRRSQQGPRKE
T682 IIATVLMTEDIKLNK
K730 RVRSILNKLTPQMFQ
K741 QMFQQLMKQVTQLAI
T750 VTQLAIDTEERLKGV
K755 IDTEERLKGVIDLIF
K792 LKVPTTEKPTVTVNF
K823 DDDEVFEKKQKEMDE
K841 AEERGRLKEELEEAR
S855 RDIARRRSLGNIKFI
K860 RRSLGNIKFIGELFK
K885 DCVVKLLKNHDEESL
K904 RLLTTIGKDLDFEKA
K910 GKDLDFEKAKPRMDQ
K924 QYFNQMEKIIKEKKT
K924 QYFNQMEKIIKEKKT
K927 NQMEKIIKEKKTSSR
S988 QQLMAKGSDKRRGGP
R992 AKGSDKRRGGPPGPP
R1002 PPGPPISRGLPLVDD
T1014 VDDGGWNTVPISKGS
K1019 WNTVPISKGSRPIDT
T1026 KGSRPIDTSRLTKIT
T1033 TSRLTKITKPGSIDS
K1034 SRLTKITKPGSIDSN
S1037 TKITKPGSIDSNNQL
S1040 TKPGSIDSNNQLFAP
S1052 FAPGGRLSWGKGSSG
K1055 GGRLSWGKGSSGGSG
S1057 RLSWGKGSSGGSGAK
S1058 LSWGKGSSGGSGAKP
S1061 GKGSSGGSGAKPSDA
S1066 GGSGAKPSDAASEAA
S1070 AKPSDAASEAARPAT
T1079 AARPATSTLNRFSAL
S1084 TSTLNRFSALQQAVP
A1089 RFSALQQAVPTESTD
T1095 QAVPTESTDNRRVVQ
S1104 NRRVVQRSSLsRERG
S1105 RRVVQRSSLsRERGE
S1107-p VVQRSSLsRERGEKA
T1139-p DRLDRARtPATKRsF
T1142 DRARtPATKRsFsKE
S1145-p RtPATKRsFsKEVEE
S1147-p PATKRsFsKEVEERS
K1148 ATKRsFsKEVEERSR
S1154 sKEVEERSRERPSQP
S1169 EGLRKAASLTEDRDR
T1171 LRKAASLTEDRDRGR
A1186 DAVKREAALPPVsPL
S1191-p EAALPPVsPLKAALS
S1198 sPLKAALSEEELEKK
Y1213 SKAIIEEYLHLNDMK
K1364 REAGLSWKEFLPEGQ
Y1384 VAEQKVEYTLGEESE
T1385 AEQKVEYTLGEESEA
S1390 EYTLGEESEAPGQRA
K1412 RQLEKLLKEGSSNQR
T1437 EQQIVSNTLVRALMT
Y1486 QKELQALYALQALVV
T1494 ALQALVVTLEQPPNL
Y1510 RMFFDALYDEDVVKE
K1540 QGKGVALKSVTAFFK
S1556 LREAEEESDHN____
  eIF4G iso8  
S15 TGPPPAPSPGLPQPA
R48 MNTPSQPRQHFYPSR
Y52 SQPRQHFYPSRAQPP
R55 RQHFYPSRAQPPSSA
R55 RQHFYPSRAQPPSSA
S61 SRAQPPSSAASRVQS
R65 PPSSAASRVQSAAPA
R73 VQSAAPARPGPAAHV
Y103 YPASQGAYYIPGQGR
R110 YYIPGQGRSTYVVPT
T179 APKRERKTIRIRDPN
K190 RDPNQGGKDITEEIM
K190 RDPNQGGKDITEEIM
T202 EIMSGARTASTPTPP
S204 MSGARTASTPTPPQT
T205 SGARTASTPTPPQTG
T207 ARTASTPTPPQTGGG
T211 STPTPPQTGGGLEPQ
G214 TPPQTGGGLEPQANG
T223 EPQANGETPQVAVIV
T301 QMSVEESTPISRETG
Y311 SRETGEPYRLSPEPT
S314 TGEPYRLSPEPTPLA
T318 YRLSPEPTPLAEPIL
S343 PESEFSSSPLQAPTP
T349 SSPLQAPTPLASHTV
S353 QAPTPLASHTVEIHE
K524 KIKELNKKEAVGDLL
S561 PGPESEGSGVPPRPE
K580 TWDSKEDKIHNAENI
K593 NIQPGEQKYEYKSDQ
K593 NIQPGEQKYEYKSDQ
Y594 IQPGEQKYEYKSDQW
K597 GEQKYEYKSDQWKPL
S598 EQKYEYKSDQWKPLN
K602 EYKSDQWKPLNLEEK
K609 KPLNLEEKKRYDREF
T647 VLDKANKTPLRPLDP
T667 INCGPDFTPSFANLG
S669 CGPDFTPSFANLGRT
R675 PSFANLGRTTLSTRG
R681 GRTTLSTRGPPrGGP
R685-m1 LSTRGPPrGGPGGEL
R694-m1 GPGGELPrGPQAGLG
R703 PQAGLGPRRsQQGPR
S705-p AGLGPRRsQQGPRKE
T723 IIATVLMTEDIKLNK
K771 RVRSILNKLTPQMFQ
K782 QMFQQLMKQVTQLAI
T791 VTQLAIDTEERLKGV
K796 IDTEERLKGVIDLIF
K833 LKVPTTEKPTVTVNF
K864 DDDEVFEKKQKEMDE
K882 AEERGRLKEELEEAR
S896 RDIARRRSLGNIKFI
K901 RRSLGNIKFIGELFK
K926 DCVVKLLKNHDEESL
K945 RLLTTIGKDLDFEKA
K951 GKDLDFEKAKPRMDQ
K965 QYFNQMEKIIKEKKT
K965 QYFNQMEKIIKEKKT
K968 NQMEKIIKEKKTSSR
S1029 QQLMAKGSDKRRGGP
R1033 AKGSDKRRGGPPGPP
R1043 PPGPPISRGLPLVDD
T1055 VDDGGWNTVPISKGS
K1060 WNTVPISKGSRPIDT
T1067 KGSRPIDTSRLTKIT
T1074 TSRLTKITKPGSIDS
K1075 SRLTKITKPGSIDSN
S1078 TKITKPGSIDSNNQL
S1081 TKPGSIDSNNQLFAP
S1093 FAPGGRLSWGKGSSG
K1096 GGRLSWGKGSSGGSG
S1098 RLSWGKGSSGGSGAK
S1099 LSWGKGSSGGSGAKP
S1102 GKGSSGGSGAKPSDA
S1107 GGSGAKPSDAASEAA
S1111 AKPSDAASEAARPAT
T1120 AARPATSTLNRFSAL
S1125 TSTLNRFSALQQAVP
A1130 RFSALQQAVPTESTD
T1136 QAVPTESTDNRRVVQ
S1145 NRRVVQRSSLsRERG
S1146 RRVVQRSSLsRERGE
S1148-p VVQRSSLsRERGEKA
T1180 DRLDRARTPATKRsF
T1183 DRARTPATKRsFSKE
S1186-p RTPATKRsFSKEVEE
S1188 PATKRsFSKEVEERS
K1189 ATKRsFSKEVEERSR
S1195 SKEVEERSRERPSQP
S1210 EGLRKAASLTEDRDR
T1212 LRKAASLTEDRDRGR
A1226 RDAVKREAALPPVsP
S1232-p EAALPPVsPLKAALs
S1239-p sPLKAALsEEELEKK
Y1254 SKAIIEEYLHLNDMK
K1405 REAGLSWKEFLPEGQ
Y1425 VAEQKVEYTLGEESE
T1426 AEQKVEYTLGEESEA
S1431 EYTLGEESEAPGQRA
K1453 RQLEKLLKEGSSNQR
T1478 EQQIVSNTLVRALMT
Y1527 QKELQALYALQALVV
T1535 ALQALVVTLEQPPNL
Y1551 RMFFDALYDEDVVKE
K1581 QGKGVALKSVTAFFK
S1597 LREAEEESDHN____
  mouse

► Hide Isoforms
 
S15-p TGPPPARsPGLPQPA
R48 MNTPSQPRQGGFRSL
Y59 FRSLQHFYPSrAQPP
R62-m1 LQHFYPSrAQPPSSA
R62 LQHFYPSRAQPPSSA
S68 SrAQPPSSAASrVQS
R72-m1 PPSSAASrVQSAAPA
R80 VQSAAPARPGPAPHV
Y110-p YSASQGAyYIPGQGr
R117-m1 yYIPGQGrSTYVVPT
T186 APKRERKTIRIRDPN
K197 RDPNQGGKDITEEIM
K197-ub RDPNQGGkDITEEIM
T209-p EIMSGARtAstPtPP
S211-p MSGARtAstPtPPQt
T212-p SGARtAstPtPPQtG
T214-p ARtAstPtPPQtGGs
T218-p stPtPPQtGGsLEPQ
S221-p tPPQtGGsLEPQPNG
S230-p EPQPNGEsPQVAVII
T311 PMSVEESTPISCETG
Y321 SCETGEPYCLSPEPT
S324 TGEPYCLSPEPTLAE
T328 YCLSPEPTLAEPILE
S352 PESEFSSSPLQVSTA
T358 SSPLQVSTALVPHKV
P362 QVSTALVPHKVETHE
K528-ub KIKELNKkEAVGDLL
S565-p PSPESEGsMVPTQPE
K584 TWDSKEDKIHNAENI
K597-ac NIQPGEQkyEYkSDQ
K597-ub NIQPGEQkyEYkSDQ
Y598-p IQPGEQkyEYkSDQW
K601-ub GEQkyEYkSDQWkPL
S602 EQkyEYkSDQWkPLN
K606-ub EYkSDQWkPLNLEEK
K613 kPLNLEEKKRYDREF
T651 VLDKANKTPLRQLDP
T671 INCGPDFTPSFANLG
S673 CGPDFTPSFANLGRP
R679 PSFANLGRPALSNRG
R685 GRPALSNRGPPrGGP
R689-m1 LSNRGPPrGGPGGEL
R698-m1 GPGGELPrGPAGLGP
R706 GPAGLGPRRsQQGPR
S708-p AGLGPRRsQQGPRKE
T726-p IISSVIMtEDIKLNK
K774-ub RVRSILNkLTPQMFQ
K785 QMFQQLMKQVTQLAI
T794-p VTQLAIDtEERLkGV
K799-ub IDtEERLkGVIDLIF
K836 LKVPTTEKPTVTVNF
K867 DDDEVFEKKQKEMDE
K885-ub AEERGRLkEELEEAR
S899 RDIARRRSLGNIkFI
K904-ub RRSLGNIkFIGELFK
K929 DCVVKLLKNHDEESL
K948 RLLTTIGKDLDFAkA
K954-ub GKDLDFAkAKPRMDQ
K968 QYFNQMEKIIKEKKT
K968 QYFNQMEKIIKEKKT
K971 NQMEKIIKEKKTSSR
S1032 QQLMAKGSDKRrGGP
R1036-m1 AKGSDKRrGGPPGPP
R1046-m1 PPGPPINrGLPLVDD
T1058-p VDDGGWNtVPISKGS
K1063 WNtVPISKGSRPIDT
T1070 KGSRPIDTSRLTKIT
T1077 TSRLTKITkPGsIDs
K1078-ub SRLTKITkPGsIDsN
S1081-p TKITkPGsIDsNNQL
S1084-p TkPGsIDsNNQLFAP
S1096-p FAPGGRLsWGKGSSG
K1099 GGRLsWGKGSSGGSG
S1101 RLsWGKGSSGGSGAK
S1102 LsWGKGSSGGSGAKP
S1105 GKGSSGGSGAKPSDT
S1110 GGSGAKPSDTAsEAT
S1114-p AKPSDTAsEATRPAT
T1121 sEATRPATLNRFsAL
S1126-p PATLNRFsALQQtLP
T1131-p RFsALQQtLPAENtD
T1137-p QtLPAENtDNRRVVQ
S1146 NRRVVQRSsLsRERG
S1147-p RRVVQRSsLsRERGE
S1149-p VVQRSsLsRERGEKA
T1181-p DRLDRARtPAtKRsF
T1184-p DRARtPAtKRsFsKE
S1187-p RtPAtKRsFsKEVEE
S1189-p PAtKRsFsKEVEERs
K1190 AtKRsFsKEVEERsR
S1196-p sKEVEERsRERPSQP
S1211-p EGLRKAAsLtEDRGR
T1213-p LRKAAsLtEDRGRDP
T1226-p DPVKREAtLPPVsPP
S1231-p EAtLPPVsPPKAALs
S1238-p sPPKAALsVDEVEKK
Y1253 SKAIIEEYLHLNDMK
R1404 REAGLSWREFLAEGQ
Y1424 VAEKKVEYTLGEESE
T1425 AEKKVEYTLGEESEA
S1430 EYTLGEESEAPGQRT
K1452-ac RQLEKLLkDGGSNQR
T1477-p EQQIASNtLVRALMT
Y1526 QKELQALYALQALVV
T1534 ALQALVVTLEQPANL
Y1550 RMFFDALYDEDVVKE
K1580 QGKGVALKSVTAFFN
S1597-p REAEDEEsDHN____
2441 : Phospho-eIF4G (Ser1108) Antibody
  eIF4G iso2  
S15 TGPPPARSPGLPQPA
R48-m2 MNTPSQPrQHFYPSr
Y52 SQPrQHFYPSrAQPP
R55 rQHFYPSRAQPPSSA
R55-m2 rQHFYPSrAQPPSSA
S61 SrAQPPSSAASRVQS
R65 PPSSAASRVQSAAPA
R73 VQSAAPARPGPAPHV
Y103 YSASQGAYYIPGQGR
R110 YYIPGQGRSTYVVPT
T179 APKRERKTIRIRDPN
K190 RDPNQGGKDITEEIM
K190 RDPNQGGKDITEEIM
T202 EIMSGARTASTPTPP
S204 MSGARTASTPTPPQT
T205 SGARTASTPTPPQTG
T207 ARTASTPTPPQTGGS
T211 STPTPPQTGGSLEPQ
S214 TPPQTGGSLEPQPNG
S223 EPQPNGESPQVAVII
T304 PMSVEESTPISCETG
Y314 SCETGEPYCLSPEPT
S317 TGEPYCLSPEPTLAE
T321 YCLSPEPTLAEPILE
S345 PESEFSSSPLQVSTA
T351 SSPLQVSTALVPHKV
- under review  
K521 KIKELNKKEAVGDLL
S558 PSPESEGSMVPTQPE
K577 TWDSKEDKIHNAENI
K590 NIQPGEQKYEYKSDQ
K590 NIQPGEQKYEYKSDQ
Y591 IQPGEQKYEYKSDQW
K594 GEQKYEYKSDQWKPL
S595 EQKYEYKSDQWKPLN
K599 EYKSDQWKPLNLEEK
K606 KPLNLEEKKRYDREF
T644 VLDKANKTPLRQLDP
T664 INCGPDFTPSFANLG
S666 CGPDFTPSFANLGRP
R672 PSFANLGRPALSNRG
R678 GRPALSNRGPPRGGP
R682 LSNRGPPRGGPGGEL
R691 GPGGELPRGPAGLGP
R699 GPAGLGPRRSQQGPR
S701 AGLGPRRSQQGPRKE
T719 IISSVIMTEDIKLNK
K767 RVRSILNKLTPQMFQ
K778 QMFQQLMKQVTQLAI
T787 VTQLAIDTEERLKGV
K792 IDTEERLKGVIDLIF
K829 LKVPTTEKPTVTVNF
K860 DDDEVFEKKQKEMDE
K878 AEERGRLKEELEEAR
S892 RDIARRRSLGNIKFI
K897 RRSLGNIKFIGELFK
K922 DCVVKLLKNHDEESL
K941 RLLTTIGKDLDFAKA
K947 GKDLDFAKAKPRMDQ
K961 QYFNQMEKIIKEKKT
K961 QYFNQMEKIIKEKKT
K964 NQMEKIIKEKKTSSR
S1025 QQLMAKGSDKRRGGP
R1029 AKGSDKRRGGPPGPP
- gap
T1044 INDGGWNTVPISKGS
K1049 WNTVPISKGSRPIDT
T1056 KGSRPIDTSRLTKIT
T1063 TSRLTKITKPGSIDS
K1064 SRLTKITKPGSIDSN
S1067 TKITKPGSIDSNNQL
S1070 TKPGSIDSNNQLFAP
S1082 FAPGGRLSWGKGSSG
K1085 GGRLSWGKGSSGGSG
S1087 RLSWGKGSSGGSGAK
S1088 LSWGKGSSGGSGAKP
S1091 GKGSSGGSGAKPSDT
S1096 GGSGAKPSDTASEAT
S1100 AKPSDTASEATRPAT
T1107 SEATRPATLNRFSAL
S1112 PATLNRFSALQQTLP
T1117 RFSALQQTLPAENTD
T1123 QTLPAENTDNRRVVQ
S1132 NRRVVQRSSLSRERG
S1133 RRVVQRSSLSRERGE
S1135 VVQRSSLSRERGEKA
T1167 DRLDRARTPATKRSF
T1170 DRARTPATKRSFSKE
S1173 RTPATKRSFSKEVEE
S1175 PATKRSFSKEVEERS
K1176 ATKRSFSKEVEERSR
S1182 SKEVEERSRERPSQP
S1197 EGLRKAASLTEDRGR
T1199 LRKAASLTEDRGRDP
T1212 DPVKREATLPPVSPP
S1217 EATLPPVSPPKAALS
S1224 SPPKAALSVDEVEKK
Y1239 SKAIIEEYLHLNDMK
R1390 REAGLSWREFLAEGQ
Y1410 VAEKKVEYTLGEESE
T1411 AEKKVEYTLGEESEA
S1416 EYTLGEESEAPGQRT
K1438 RQLEKLLKDGGSNQR
T1463 EQQIASNTLVRALMT
Y1512 QKELQALYALQALVV
T1520 ALQALVVTLEQPANL
Y1536 RMFFDALYDEDVVKE
K1566 QGKGVALKSVTAFFN
S1583 REAEDEESDHN____
  rat

 
S15 TGPPPARSPGLPQPA
R48 MNTPSQPRQGGFRSL
Y59 FRSLQHFYPSRAQPP
R62 LQHFYPSRAQPPSSA
R62 LQHFYPSRAQPPSSA
S68 SRAQPPSSAASRVQS
R72 PPSSAASRVQSAAPA
R80 VQSAAPARPGPAPHV
Y110 YSASQGAYYIPGQGR
R117 YYIPGQGRSTYVVPT
T186 APKRERKTIRIRDPN
K197 RDPNQGGKDITEEIM
K197 RDPNQGGKDITEEIM
T209 EIMSGARTAStPTPP
S211 MSGARTAStPTPPQT
T212-p SGARTAStPTPPQTG
T214 ARTAStPTPPQTGGS
T218 StPTPPQTGGSLEPQ
S221 TPPQTGGSLEPQPNG
S230 EPQPNGESPQVAVII
T311 PISVEESTPISCESG
Y321 SCESGEPYCLSPEPT
S324 SGEPYCLSPEPTLAE
T328 YCLSPEPTLAEPILE
S352 PESEFSSSPLQVSTS
- under review  
- under review  
K526 KIKELNKKEAVGDLL
S563 PSPESEGSAALPQPE
K582 TWDSKEDKIHNAENI
K595 NIQPGEQKYEYKSDQ
K595 NIQPGEQKYEYKSDQ
Y596 IQPGEQKYEYKSDQW
K599 GEQKYEYKSDQWKPL
S600 EQKYEYKSDQWKPLN
K604 EYKSDQWKPLNLEEK
K611 KPLNLEEKKRYDREF
T649 VLDKANKTPLRSLDP
T669 INCGPDFTPSFANLG
S671 CGPDFTPSFANLGRP
R677 PSFANLGRPTLSSRG
R683 GRPTLSSRGPPrGGP
R687-m1 LSSRGPPrGGPGGEL
R696 GPGGELPRGPAGLGP
R704 GPAGLGPRRSQQGPR
S706 AGLGPRRSQQGPRKE
T724 IISSVIMTEDIKLNK
K772 RVRSILNKLTPQMFQ
K783 QMFQQLMKQVTQLAI
T792 VTQLAIDTEERLKGV
K797 IDTEERLKGVIDLIF
K834 LKVPTTEKPTVTVNF
K865 DDDEVFEKKQKEMDE
K883 AEERGRLKEELEEAR
S897 RDIARRRSLGNIKFI
K902 RRSLGNIKFIGELFK
K927 DCVVKLLKNHDEESL
K946 RLLTTIGKDLDFAKA
K952 GKDLDFAKAKPRMDQ
K966 QYFNQMEKIIKEKKT
K966 QYFNQMEKIIKEKKT
K969 NQMEKIIKEKKTSSR
G1030 QQLMAKGGDKRRGGP
R1034 AKGGDKRRGGPPGPP
R1044 PPGPPVNRGLPLVDD
T1056 VDDGGWNTVPISKGS
K1061 WNTVPISKGSRPIDT
T1068 KGSRPIDTSRLTKIT
T1075 TSRLTKITKPGSIDS
K1076 SRLTKITKPGSIDSN
S1079 TKITKPGSIDSNNQL
S1082 TKPGSIDSNNQLFAP
S1094 FAPGGRLSWGKGSSG
K1097 GGRLSWGKGSSGGSG
S1099 RLSWGKGSSGGSGAK
S1100 LSWGKGSSGGSGAKP
S1103 GKGSSGGSGAKPsDT
S1108-p GGSGAKPsDTASEAT
S1112 AKPsDTASEATRPAT
T1119 SEATRPATLNRFSAL
S1124 PATLNRFSALQQTLP
T1129 RFSALQQTLPVENTD
T1135 QTLPVENTDNRRVVQ
S1144 NRRVVQRSSLsRERG
S1145 RRVVQRSSLsRERGE
S1147-p VVQRSSLsRERGEKA
T1179 DRLDRARTPATKRsF
T1182 DRARTPATKRsFsKE
S1185-p RTPATKRsFsKEVEE
S1187-p PATKRsFsKEVEERS
K1188 ATKRsFsKEVEERSR
S1194 sKEVEERSRERPSQP
S1209-p EGLRKAAsLTEDRGR
T1211 LRKAAsLTEDRGRDP
T1224 DPVKREATLPPVsPP
S1229-p EATLPPVsPPKAALA
A1236 sPPKAALAVDEVERK
Y1251 SKAIIEEYLHLNDMK
R1402 REAGLSWREFLAEGQ
Y1422 VAEKKVEYTLGEESE
T1423 AEKKVEYTLGEESEA
S1428 EYTLGEESEAPGQRA
K1450 RQLEKLLKDGGSNQR
T1475 EQQIASNTLVRALMT
Y1524 QKELQALYALQALVV
T1532 ALQALVVTLEQPANL
Y1548 RMFFDALYDEDVVKE
K1578 QGKGVALKSVTAFFN
S1595-p REAEDEEsDHN____
2441 : Phospho-eIF4G (Ser1108) Antibody
  rabbit

 
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
T6 __MSGARTVSTPTPP
S8 MSGARTVSTPTPPQT
T9 SGARTVSTPTPPQTG
T11 ARTVSTPTPPQTGGG
T15 STPTPPQTGGGVEPQ
G18 TPPQTGGGVEPQANG
T27 EPQANGETPQVAVIV
A107 QMPVEEPAPISREAG
Y117 SREAGEPYCLSPEPT
S120 AGEPYCLSPEPTPLA
T124 YCLSPEPTPLAEPIL
S149 PVSEFSSSPIQVLTP
T155 SSPIQVLTPLASHKM
S159 QVLTPLASHKMEIHE
K329 KIKELNKKEAVGDLL
S366 PTPESEGSSGPSRPE
K385 TWDAKEDKIHNAENI
K398 NIQPGEQKYEYKSDQ
K398 NIQPGEQKYEYKSDQ
Y399 IQPGEQKYEYKSDQW
K402 GEQKYEYKSDQWRPL
S403 EQKYEYKSDQWRPLN
R407 EYKSDQWRPLNLEEK
K414 RPLNLEEKKRYDREF
T452 VLEKANKTPLRPLDP
T472 INCGPDFTPSFANLG
S474 CGPDFTPSFANLGRP
R480 PSFANLGRPALSSRG
R486 GRPALSSRGPPRGGP
R490 LSSRGPPRGGPGGEL
R499 GPGGELPRGAAGLGP
R507 GAAGLGPRRSLQPRP
S509 AGLGPRRSLQPRPPK
T528 LIASVIMTEDIKLNK
K576 RVRSILNKLTPQMFQ
K587 QMFQQLMKQVTQLAI
T596 VTQLAIDTEGASKGS
K601 IDTEGASKGSLTSSL
K637 AESATTEKPTVTVNF
K668 DDDEVFEKKQKEMDE
K686 AEERERLKEELEEAR
S700 RDIARRCSLGNIKFI
K705 RCSLGNIKFIGELFK
- gap
K748 RLLTTIGKDLDFEKA
K754 GKDLDFEKAKPRMDQ
K768 QYFNQMEKIIKEKKT
K768 QYFNQMEKIIKEKKT
K771 NQMEKIIKEKKTSSR
S832 QQLMAKGSDKRRGGP
R836 AKGSDKRRGGPPGPP
R846 PPGPPISRGLPLVDD
T858 VDDGGWNTVPISKGS
K863 WNTVPISKGSRPIDT
T870 KGSRPIDTSRLTKIT
T877 TSRLTKITKPGSIDS
K878 SRLTKITKPGSIDSN
S881 TKITKPGSIDSNNQL
S884 TKPGSIDSNNQLFAP
S896 FAPGGRLSWGKGSSG
K899 GGRLSWGKGSSGSGA
S901 RLSWGKGSSGSGAKP
S902 LSWGKGSSGSGAKPS
S904 WGKGSSGSGAKPSDA
S909 SGSGAKPSDAASEVS
S913 AKPSDAASEVSRPAT
T922 VSRPATSTLNRFSAL
S927 TSTLNRFSALQQAVP
A932 RFSALQQAVPTESTD
T938 QAVPTESTDNRRVVQ
S947 NRRVVQRSSLSRERG
S948 RRVVQRSSLSRERGG
S950 VVQRSSLSRERGGKA
T982 DRLDRARTPATKRSF
T985 DRARTPATKRSFSKE
S988 RTPATKRSFSKEVEE
S990 PATKRSFSKEVEERS
K991 ATKRSFSKEVEERSR
S997 SKEVEERSRERPSQP
S1012 EGLRKAASLTEDRDR
T1014 LRKAASLTEDRDRGR
A1029 DAAKREAALPPVSCA
S1034 EAALPPVSCAKAALS
S1041 SCAKAALSEEELEKK
Y1056 SKAIIEEYLHLNDMK
K1207 VRLGSAGKNFCLEGQ
Y1227 ITEQKVEYTLGEESE
T1228 TEQKVEYTLGEESEA
S1233 EYTLGEESEAPGQRA
K1255 RQLEKVLKEGSSNQR
T1280 EQQIASNTLVRALMT
Y1328 AEGAARLYALQALVV
T1336 ALQALVVTLEQPANL
Y1352 RMFFDALYDEDVVKE
K1382 QGKGVALKSVTAFFK
S1399 REVEEEESDHN____
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.