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Protein Page:
AIDA-1b (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
AIDA-1b Isoform 2 may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells. 8 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion
Cellular Component: Cajal body; postsynaptic membrane; cytoplasm; postsynaptic density; plasma membrane; cell junction
Molecular Function: ephrin receptor binding
Reference #:  Q7Z6G8 (UniProtKB)
Alt. Names/Synonyms: AIDA; AIDA-1; amyloid-beta precursor protein intracellular domain associated protein 1; Amyloid-beta protein intracellular domain-associated protein 1; ANKS1B; ANKS2; ankyrin repeat and sterile alpha motif domain containing 1B; Ankyrin repeat and sterile alpha motif domain-containing protein 1B; ANS1B; cajalin 2; cajalin-2; E2A-PBX1-associated protein; EB-1; EB1; MGC26087
Gene Symbols: ANKS1B
Molecular weight: 138,066 Da
Basal Isoelectric point: 5.93  Predict pI for various phosphorylation states
Select Structure to View Below

AIDA-1b
Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  RCSB PDB  |  Phospho3D  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

► Hide Isoforms 		 
0 1 - gap
0 1 - gap
0 1 - gap
0 1 T303-p EPVQEDAtQETHISS
0 2 S309 AtQETHISSPVESPS
0 3 S310 tQETHISSPVESPSQ
0 3 S314 HISSPVESPSQKTKS
0 1 T319 VESPSQKTKSETVtG
0 1 T325-p KTKSETVtGELSKLL
0 1 S353 EDLCHTISDHYLDNL
0 2 S364 LDNLSKISEEELGKN
0 1 - gap
0 1 - gap
0 2 T503 RNSSTGPTPDCSPPS
0 4 S507 TGPTPDCSPPSPDTA
0 4 S510 TPDCSPPSPDTALKN
0 1 S531 PQPKQRTSIVSSLDF
0 1 T689-p ENHTIVGtRSTRSGS
0 4 S738 LSKSVSKSDSDLIAY
0 6 Y901-p DSIELGDyTKAFLIN
0 2 S942-p HRKRILAsLGDRLHD
0 7 K954 LHDDPPQKPPRSITL
0 2 S965 SITLREPSGNHTPPQ
0 1 T969 REPSGNHTPPQLSPS
0 2 S974 NHTPPQLSPSLSQST
0 1 S976 TPPQLSPSLSQSTYT
0 1 S987 STYTTGGSLDVPHII
0 112 Y1007-p RRRRNENyFDDIPRS
0 1 S1014 yFDDIPRSKLERQMA
0 1 K1073 YLGSMLIKELRGtEs
0 1 T1078-p LIKELRGtEstQDAC
0 1 S1080-p KELRGtEstQDACAK
0 1 T1081-p ELRGtEstQDACAKM
0 1 K1087 stQDACAKMRANCQK
0 1 K1094 KMRANCQKSTEQMKK
0 1 T1104-p EQMKKVPtIILSVSY
0 1 K1115 SVSYKGVKFIDATNK
0 2 T1200 RKGGHSSTLPESFEN
0 1 K1208 LPESFENKPSKPIPK
0 1 K1211 SFENKPSKPIPKPRV
0 4 S1223 PRVSIRKSVDLLHAS
0 1 - gap
0 1 F1248 TEEALRKF_______
  AIDA-1b iso2  
Y14-p LSAQDYRyyPVDGYS
Y15-p SAQDYRyyPVDGYSL
S21 yyPVDGYSLLKRFPL
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
Y127 DSIELGDYTKAFLIN
S168 HRKRILASLGDRLHD
K180 LHDDPPQKPPRSITL
- gap
- gap
- gap
- gap
- gap
- gap
- gap
K239 YLGSMLIKELRGTES
T244 LIKELRGTESTQDAC
S246 KELRGTESTQDACAK
T247 ELRGTESTQDACAKM
K253 STQDACAKMRANCQK
K260 KMRANCQKSTEQMKK
T270 EQMKKVPTIILSVSY
K281 SVSYKGVKFIDATNK
T366 RKGGHSSTLPESFEN
K374 LPESFENKPSKPIPK
K377 SFENKPSKPIPKPRV
S389 PRVSIRKSVDLLHAS
- gap
F414 TEEALRKF_______
  mouse

► Hide Isoforms 		 
- gap
- gap
- gap
A304 EHAQEDTAQETHLss
S310-p TAQETHLssPAEsPQ
S311-p AQETHLssPAEsPQK
S315-p HLssPAEsPQKTKSE
T319 PAEsPQKTKSETVTG
T325 KTKSETVTGELSKLL
S353-p EDLCHTIsDHYLDNL
S364-p LDNLSKIsEEELGKN
- gap
- gap
T503-p RNSSTGPtPDCsPPs
S507-p TGPtPDCsPPsPDTA
S510-p tPDCsPPsPDTALKN
S531-p PQPKQRTsIVSSLDF
T689 ENHTIVGTRMSRSGS
S738-p LSKNVSKsDSDLIAY
Y900-p DSIELGDyTKAFLIN
S941 HRKRILASLGDRLHD
K953-u LHDDPPQkPPRSITL
S964-p SITLREPsGNHtPPQ
T968-p REPsGNHtPPQLsPs
S973-p NHtPPQLsPsLSQST
S975-p tPPQLsPsLSQSTYT
S986-p STYTTGGsLDVPHII
Y1006-p RRRRNENyFDDIPRs
S1013-p yFDDIPRsKLERQMA
K1072-u YLGSMLIkELRGTES
T1077 LIkELRGTESTQDAC
S1079 kELRGTESTQDACAK
T1080 ELRGTESTQDACAKM
K1086 STQDACAKMRANCRK
K1093 KMRANCRKSTEQMKK
T1103 EQMKKVPTIILSVSY
K1114-u SVSYKGVkFIDAANK
T1199-p RKGGHSStLPESFEN
K1207 LPESFENKPSKPIPK
K1210 SFENKPSKPIPKPRV
S1222-p PRVSIRKsVQIDPSE
K1231-u QIDPSEQkTLANLPW
Y1254 KRGINTKYETTIF__
  AIDA-1b iso2  
Y14 PSAPDYRYYPVDGYs
Y15 SAPDYRYYPVDGYsL
S21-p YYPVDGYsLLKRFPL
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
Y127 DSIELGDYTKAFLIN
S168 HRKRILASLGDRLHD
K180 LHDDPPQKPPRSITL
- gap
- gap
- gap
- gap
- gap
- gap
- gap
K239 YLGSMLIKELRGTES
T244 LIKELRGTESTQDAC
S246 KELRGTESTQDACAK
T247 ELRGTESTQDACAKM
K253 STQDACAKMRANCRK
K260 KMRANCRKSTEQMKK
T270 EQMKKVPTIILSVSY
K281 SVSYKGVKFIDAANK
T366 RKGGHSSTLPESFEN
K374 LPESFENKPSKPIPK
K377 SFENKPSKPIPKPRV
S389-p PRVSIRKsVQIDPSE
K398 QIDPSEQKTLANLPW
Y421 KRGINTKYETTIF__
  AIDA-1b iso7  
- gap
- gap
- gap
- gap
S47 TAQETHLSSPAESPQ
S48 AQETHLSSPAESPQK
S52 HLSSPAESPQKTKSE
T56 PAESPQKTKSETVTG
T62 KTKSETVTGELSKLL
S90 EDLCHTISDHYLDNL
S101 LDNLSKISEEELGKN
S110-p EELGKNGsQSVVsKG
S115-p NGsQSVVsKGGGTKT
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
  rat

 
- gap
- gap
- gap
A304 EHAQEDTAQETRLss
S310-p TAQETRLssPAQSPS
S311-p AQETRLssPAQSPSQ
S315 RLssPAQSPSQKtKS
T320-p AQSPSQKtKSETVTG
T326 KtKSETVTGELSKLL
S354 EDLCHTISDHYLDNL
S365 LDNLSKISEEELGKN
- gap
- gap
T504 RNSSTGPTPDCSPPS
S508 TGPTPDCSPPSPDTA
S511 TPDCSPPSPDTALKN
S532 PQPKQRTSIVSSLDF
T690 ENHTIVGTRMSRGGS
S739 LSKNVSKSDSDLIAY
Y901-p DSIELGDyTKAFLIN
S942 HRKRILASLGDRLHE
K954-u LHEDPPQkPPRSITL
S965-p SITLREPsGNHTPPQ
T969 REPsGNHTPPQLsPs
S974-p NHTPPQLsPsLSQST
S976-p TPPQLsPsLSQSTYT
S987 STYTTGGSLDVPHII
Y1007-p RRRRNENyFDDIPRS
S1014 yFDDIPRSKLERQMA
K1073 YLGSMLIKELRGTES
T1078 LIKELRGTESTQDAC
S1080 KELRGTESTQDACAk
T1081 ELRGTESTQDACAkM
K1087-u STQDACAkMRANCQk
K1094-u kMRANCQkSTEQMKK
T1104 EQMKKVPTIILSVSY
K1115 SVSYKGVKFIDAANK
T1200 RKGGHSSTLPESFEN
K1208-u LPESFENkPSkPIPK
K1211-u SFENkPSkPIPKPRV
S1223 PRVSIRKSVQIDPSE
K1232 QIDPSEQKTLANLPW
Y1255-p KRGINTKyETTIF__
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