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TNFL9 (human)

Overview TNFL9 Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. Belongs to the tumor necrosis factor family. Note: This description may include information from UniProtKB. Protein type: Apoptosis; Cytokine; Cell cycle regulation; Membrane protein, integral Cellular Component: extracellular space; integral to membrane; plasma membrane Molecular Function: cytokine activity; tumor necrosis factor receptor binding; receptor binding Biological Process: cell proliferation; cell-cell signaling; apoptosis; immune response; signal transduction; regulation of cell proliferation Reference #:  P41273 (UniProtKB) Alt. Names/Synonyms: TNFSF9 Gene Symbols: TNFSF9 Molecular weight: 26,625 Da Basal Isoelectric point: 6.52  Predict pI for various phosphorylation states

Select Structure to View Below TNFL9 2X29 - A=80-246 (human)

STRING  |  Scansite  |  Phospho.ELM  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  DISEASE  |  Source  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept

	Modification Sites and Domains

	Modification Sites in Parent Protein, Orthologs, and Isoforms

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		Y3	_____MEYASDASLD
0	1		-	under review
0	1		S158-p	RVVAGEGsGSVSLAL
0	1		S172-p	LHLQPLRsAAGAAAL
0	1		T182-p	GAAALALtVDLPPAS
0	1		S190-p	VDLPPASsEARNSAF

	mouse
Y58-p	ALPTDAAyPAVNVRD
S168-p	NTTLNWHsQDGAGSS
Q218	TNTGHKVQGWVSLVL
-	under review
T240	DFDNLALTVELFPCS
-	under review

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