Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. Belongs to the tumor necrosis factor family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Cell cycle regulation; Cytokine; Apoptosis
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: extracellular space; plasma membrane; integral to membrane
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.