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ZNF259 (human)

Overview ZNF259 May be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus. Binds to the EGF and PDGF receptors. Binds to the elongation factor 1-alpha EF1A. Component of an import snRNP complex composed of KPNB1, SNUPN, SMN1 and ZNF259. Belongs to the ZPR1 family. Note: This description may include information from UniProtKB. Protein type: Cell cycle regulation Cellular Component: cytoplasm; nucleolus; nucleus Molecular Function: zinc ion binding Biological Process: cell proliferation; signal transduction Reference #:  O75312 (UniProtKB) Alt. Names/Synonyms: MGC110983; Zinc finger protein 259; Zinc finger protein ZPR1; ZNF259; ZPR1 Gene Symbols: ZNF259 Molecular weight: 50,925 Da Basal Isoelectric point: 4.66  Predict pI for various phosphorylation states Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below ZNF259 2QKD - A=47-440 (mouse)

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	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		S49-p	QQPTEIEsLCMNCYC
0	1		T65-p	GMTRLLLtkIPFFRE
0	1		K66-u	MTRLLLtkIPFFREI
0	1		K119-u	DMNREVVkTDSAATR
0	2		K140-u	EIPAFSQkGALTTVE
0	1		S190-p	KELKQVAsPFTLIID
0	93		K299-u	GHRTNEVkSGGAVEP
0	27		Y451-p	NDMKTEGyEAGLAPQ

	mouse
S49	QQPTEIESLCMNCYR
T65	GTTRLLLTKIPFFRE
K66	TTRLLLTKIPFFREI
K119	DMNREVVKTDSATTR
K140	EIPAFSQKGALTTVE
S190	KDLKQMASPFTLVID
K299-u	GHRTNEVkSGGAVEP
Y451	NDMKTEGYEAGLAPQ

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