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Protein Page:
WNT5B (human)

Overview
WNT5B Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Interacts with PORCN. Belongs to the Wnt family. Note: This description may include information from UniProtKB.
Protein type: Secreted, signal peptide; Secreted
Cellular Component: proteinaceous extracellular matrix; extracellular space; cell surface; Golgi lumen; endoplasmic reticulum lumen; extracellular region; plasma membrane
Molecular Function: frizzled binding; receptor binding
Biological Process: fat cell differentiation; neuron differentiation; cell fate commitment; Wnt receptor signaling pathway; wound healing; positive regulation of fat cell differentiation; chondrocyte differentiation; positive regulation of cell migration
Reference #:  Q9H1J7 (UniProtKB)
Alt. Names/Synonyms: MGC2648; Protein Wnt-5b; wingless-type MMTV integration site family, member 5B; WNT-5B protein; WNT5B
Gene Symbols: WNT5B
Molecular weight: 40,323 Da
Basal Isoelectric point: 8.8  Predict pI for various phosphorylation states
CST Pathways:  ESC Pluripotency and Differentiation  |  Microtubule Dynamics  |  mTOR Signaling  |  Translation: eIF4E and p70S6K  |  Wnt/├č-Catenin Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

WNT5B

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 3 Y249-p GDRLKEKyDSAAAMR
0 1 S293-p DYCLRNEsTGSLGTQ
  mouse

 
Y249 GDRLKEKYDSAAAMR
T293 DYCLRNETTGSLGTQ
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