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WIF1 (human)

Overview WIF1 Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. Note: This description may include information from UniProtKB. Protein type: Secreted, signal peptide; Secreted; Inhibitor protein Cellular Component: extracellular region Biological Process: Wnt receptor signaling pathway; multicellular organismal development; positive regulation of fat cell differentiation; signal transduction Reference #:  Q9Y5W5 (UniProtKB) Alt. Names/Synonyms: WIF-1; WIF1; WNT inhibitory factor 1 Gene Symbols: WIF1 Molecular weight: 41,528 Da Basal Isoelectric point: 7.84  Predict pI for various phosphorylation states CST Pathways:  Wnt/ß-Catenin Signaling Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below WIF1 2D3J - A=32-181 (human) 2YGN - A=35-178 (human) 2YGO - A=35-210 (human) 2YGP - A=35-210 (human) 2YGQ - A=35-346 (human)

STRING  |  Scansite  |  Phospho.ELM  |  Pfam  |  RCSB PDB 2D3J 2YGN 2YGO 2YGP 2YGQ  |  ENZYME  |  Phospho3D  |  DISEASE  |  Source  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains

	Modification Sites in Parent Protein, Orthologs, and Isoforms

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	1		T215-p	HCEKALCtPRCMNGG
0	1		T255-p	TTCFNGGtCFYPGKC

	mouse
I215	HCEKALCIPRCMNGG
T255	TTCFNGGTCFYPGKC

	rat
I215	HCEKALCIPRCMNGG
T255	ATCFNGGTCFYPGKC

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