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Protein Page:
CDH11 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
CDH11 Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Interacts with PCDH8. Expressed mainly in brain but also found in other tissues. Expressed in neuroblasts. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Motility/polarity/chemotaxis; Membrane protein, integral
Cellular Component: cytoplasm; plasma membrane; integral to membrane
Molecular Function: calcium ion binding
Biological Process: intercellular junction assembly and maintenance; ossification; corticospinal tract morphogenesis; homophilic cell adhesion; cell adhesion; skeletal development
Reference #:  P55287 (UniProtKB)
Alt. Names/Synonyms: CAD11; cadherin 11, type 2; cadherin 11, type 2, OB-cadherin (osteoblast); Cadherin-11; CDH11; CDHOB; OB; OB-cadherin; OSF-4; Osteoblast cadherin
Gene Symbols: CDH11
Molecular weight: 87,965 Da
Basal Isoelectric point: 4.75  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

CDH11

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K43-ac HGHHEKGkEGQVLQR
0 1 S93-p GNIKYILsGEGAGtI
0 1 T99-p LsGEGAGtIFVIDDK
0 1 T219-p AQTGIIRtALPNMDR
0 1 Y568 SRQKQDLYLLPIVIS
0 2 Y700-p RKDIKPEyQyMPRPG
0 1 Y702-p DIKPEyQyMPRPGLR
0 4 S714-p GLRPAPNsVDVDDFI
0 1 Y786 FKKLADLYGsKDTFD
0 10 S788-p KLADLYGsKDTFDDD
0 2 T791 DLYGsKDTFDDDS__
  mouse

 
K43 HGHHEKGKEGQVLQR
S93 GNIKYILSGEGAGTI
T99 LSGEGAGTIFVIDDK
T219 AQTGIIRTALPNMDR
Y568-p SRQKQDFyLLPIVIS
Y700 RKDIKPEYQYMPRPG
Y702 DIKPEYQYMPRPGLR
S714-p GLRPAPNsVDVDDFI
Y786-p FKKLADLyGsKDtFD
S788-p KLADLyGsKDtFDDD
T791-p DLyGsKDtFDDDS__
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