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Protein Page:
IFNA6 (human)

Overview
IFNA6 Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9p22
Cellular Component: extracellular space; extracellular region
Molecular Function: interferon-alpha/beta receptor binding; cytokine activity
Biological Process: B cell proliferation; adaptive immune response; response to exogenous dsRNA; cytokine and chemokine mediated signaling pathway; B cell differentiation; regulation of MHC class I biosynthetic process; natural killer cell activation during immune response; innate immune response; blood coagulation; defense response to virus; humoral immune response; T cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein
Reference #:  P05013 (UniProtKB)
Alt. Names/Synonyms: IFN-alpha-6; IFNA6; Interferon alpha-54; Interferon alpha-6; Interferon alpha-K; interferon, alpha 6; LeIF K
Gene Symbols: IFNA6
Molecular weight: 22,141 Da
Basal Isoelectric point: 6.9  Predict pI for various phosphorylation states
Select Structure to View Below

IFNA6

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S31-p CDLPQTHsLGHRRtM
0 1 T37-p HsLGHRRtMMLLAQM
0 1 S176-p AEIMRSFsSSRNLQE
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