a chaperone protein that translocates rapidly from the cytoplasm to the nucleus, and especially to the nucleoli, upon heat shock.Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Interacts with DNAJC3. Interacts with SRPK1. Note: This description may include information from UniProtKB.
Protein type: Chaperone
Cellular Component: nucleolus; nucleus; cytosol
Molecular Function: protein binding; ATPase activator activity; chaperone binding; unfolded protein binding; Hsp70 protein binding; ATPase binding
Biological Process: chaperone cofactor-dependent protein folding; positive regulation of ATPase activity; response to unfolded protein
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.