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ACAT2
The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. [provided by RefSeq, Jul 2008]
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| Protein type: Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Carbohydrate Metabolism - propanoate; Lipid Metabolism - synthesis and degradation of ketone bodies; Acetyltransferase; Lipid Metabolism - fatty acid; EC 2.3.1.9; Carbohydrate Metabolism - pyruvate; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - butanoate |
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Cellular Component: mitochondrion; cytoplasm; nucleolus; nucleus
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Molecular Function: acetyl-CoA C-acetyltransferase activity
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Biological Process: lipid metabolic process
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Reference #:
Q9BWD1 (UniProtKB)
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| Alt. Names/Synonyms: ACAT2; acetoacetyl Coenzyme A thiolase; Acetyl-CoA acetyltransferase, cytosolic; Acetyl-CoA transferase-like protein; acetyl-Coenzyme A acetyltransferase 2; ACTL; Cytosolic acetoacetyl-CoA thiolase; THIC |
| Gene Symbols: ACAT2 |
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Molecular weight: 41,351 Da
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Basal Isoelectric point: 6.47
Predict pI for various phosphorylation states
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Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®
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