Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
LAMA1 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
LAMA1 Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Note: This description may include information from UniProtKB.
Protein type: Extracellular matrix; Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis
Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; laminin-3 complex; laminin-1 complex; extracellular region; basement membrane; intercellular junction
Molecular Function: protein binding; extracellular matrix structural constituent; glycosphingolipid binding; receptor binding
Biological Process: regulation of cell adhesion; axon guidance; extracellular matrix organization and biogenesis; cell surface receptor linked signal transduction; regulation of embryonic development; morphogenesis of an epithelial sheet; establishment of epithelial cell polarity; cell adhesion; regulation of cell migration
Reference #:  P25391 (UniProtKB)
Alt. Names/Synonyms: LAMA; LAMA1; Laminin A chain; Laminin subunit alpha-1; laminin, alpha 1; Laminin-1 subunit alpha; Laminin-3 subunit alpha; S-LAM alpha; S-laminin subunit alpha
Gene Symbols: LAMA1
Molecular weight: 337,084 Da
Basal Isoelectric point: 5.93  Predict pI for various phosphorylation states
Select Structure to View Below

LAMA1

Protein Structure Not Found.


STRING  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  Source  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S31-p PAILNLAsNAHISTN
0 2 Y337-p HNKAKDCyYDESVAK
0 1 S348-p SVAKQKKsLNtAGQF
0 1 T351-p KQKKsLNtAGQFRGG
0 4 K486-ac GKACDRCkPGFyNLK
0 1 Y490-p DRCkPGFyNLKEKNP
0 1 S553-p LGGRHQVsINNTAVM
0 1 T581-p AYLGNKLtAFGGFLK
0 1 Y683-p NSAKMALyRLESVSL
0 1 T1426-p CLNCGDNtAGDHCDV
0 1 S1436-p DHCDVCTsGYyGKVT
0 1 Y1439-p DVCTsGYyGKVTGSA
0 1 S1505 NPQTPGGSCQKCDCN
0 1 K1508 TPGGSCQKCDCNPHG
0 1 S1516 CDCNPHGSVHGDCDR
0 1 G1519 NPHGSVHGDCDRTSG
0 1 K1616-ac NMQKDLGkIKLEGVA
0 2 K1953 QRSSRFLKEGNNLSR
0 1 T2187-p WDLGSGStRLEFPDF
0 1 S2474-p TFDLLRNsyGVRkGC
0 1 Y2475-p FDLLRNsyGVRkGCL
0 1 K2479-m1 RNsyGVRkGCLLEPI
0 1 S2508 PKSLSPESEWLVTFA
0 1 E2509 KSLSPESEWLVTFAT
0 1 T2516 EWLVTFATTNSSGII
0 1 S2615-p KLGTLVEsRTINVSN
0 1 Y2753 FASSGLIYYMAHQNQ
0 1 Y2754 ASSGLIYYMAHQNQA
0 1 T2922-p NITLEFRtSSQNGVL
0 1 S2933-p NGVLLGIsTAKVDAI
  mouse

 
T38 PAILNLATNAHISAN
Y344 HNKAKDCYYDSSVAK
S355 SVAKERRSLNTAGQY
T358 KERRSLNTAGQYSGG
K493-ac GKNCDRCkPGFYNLK
Y497 DRCkPGFYNLKERNP
S560 LGGHRQISINNTAVM
T588 AYLGNKLTAFGGFLK
Y690 NSAKMALYRLDSVSL
T1433 CLSCRDHTSGDHCEL
S1443 DHCELCASGYYGKVT
Y1446 ELCASGYYGKVTGLP
S1512-p NPRAAGGsCQtCDCN
T1515-p AAGGsCQtCDCNPQG
S1523-p CDCNPQGsVHsDCDR
S1526-p NPQGsVHsDCDRASG
E1623 NAKKIRAEIQLEGIA
K1961-ac QRSSRFLkESVGTRR
T2195 WDLGSGSTRLEFPEV
S2482 TFDLLRNSYGVRKGC
Y2483 FDLLRNSYGVRKGCA
K2487 RNSYGVRKGCALEPI
S2516-p PKSLSPEssLLATFA
S2517-p KSLSPEssLLATFAt
T2524-p sLLATFAtKNSSGIL
G2622 KLGPLTEGKTIDISN
Y2762-p FASSGLIyyVAHQNQ
Y2763-p ASSGLIyyVAHQNQM
T2931 NITLEFRTTSKNGVL
S2942 NGVLLGISSAKVDAI
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.