liprin alpha 2
Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. Belongs to the liprin family. Liprin-alpha subfamily. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 12q21.31
Cellular Component: cell surface; cytoplasm; presynaptic active zone; cytosol
Molecular Function: protein binding; protein complex binding
Alt. Names/Synonyms: FLJ41378; LIPA2; liprin-alpha 2; Liprin-alpha-2; MGC132572; PPFIA2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2; protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2; PTPRF-interacting protein alpha-2
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.