DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. Heterodimer of a small subunit and a large subunit. Belongs to the eukaryotic-type primase small subunit family. Note: This description may include information from UniProtKB.
Protein type: Transferase; DNA replication; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; EC 2.7.7.-
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: nucleoplasm; membrane
Molecular Function: DNA primase activity; metal ion binding
Biological Process: telomere maintenance via semi-conservative replication; DNA replication initiation; telomere maintenance via recombination; DNA replication, synthesis of RNA primer; DNA strand elongation during DNA replication; mitotic cell cycle; telomere maintenance; G1/S transition of mitotic cell cycle
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.