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Protein Page:
EDIL3 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
EDIL3 Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Secreted, signal peptide; Secreted; Cell adhesion
Molecular Function: integrin binding; calcium ion binding
Biological Process: multicellular organismal development; cell adhesion
Reference #:  O43854 (UniProtKB)
Alt. Names/Synonyms: DEL1; developmental endothelial locus-1; Developmentally-regulated endothelial cell locus 1 protein; EDIL3; EGF-like repeat and discoidin I-like domain-containing protein 3; EGF-like repeats and discoidin I-like domains 3; Integrin-binding protein DEL1; MGC26287
Gene Symbols: EDIL3
Molecular weight: 53,765 Da
Basal Isoelectric point: 7.08  Predict pI for various phosphorylation states
Select Structure to View Below

EDIL3

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K244-ub IGSPEYIkSyKIAyS
0 1 Y246-p SPEYIkSyKIAySND
0 1 Y250-p IkSyKIAySNDGKTW
0 1 Y260-p DGKTWAMyKVKGTNE
0 1 T336-ga HIQDYQItASSIFRT
0 1 Y452-p NVIDPPIyARHIRIL
  mouse

 
K244 IGSPEYIKSYKIAYS
Y246 SPEYIKSYKIAYSND
Y250 IKSYKIAYSNDGKTW
Y260 DGKTWAMYKVKGTNE
T336 HIQDYQITASSVFRT
Y452 NVIDPPIYARFIRIL
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