Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline. Belongs to the choline/ethanolamine kinase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 18.104.22.168; Lipid Metabolism - glycerophospholipid; EC 22.214.171.124; Kinase, other
Cellular Component: cytosol
Molecular Function: choline binding; signal transducer activity; protein homodimerization activity; cholinesterase activity; drug binding; choline kinase activity; ethanolamine kinase activity; ATP binding
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.