Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jul 2008]
Protein type: Carbohydrate Metabolism - starch and sucrose; Secreted, signal peptide; EC 18.104.22.168; Hydrolase; Secreted
Cellular Component: extracellular space; extracellular region
Molecular Function: alpha-amylase activity; calcium ion binding; chloride ion binding
Biological Process: polysaccharide digestion; carbohydrate catabolic process; carbohydrate metabolic process
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.