Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
USP54 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
USP54 Has no peptidase activity. Belongs to the peptidase C19 family. 7 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Ubiquitin conjugating system; Ubiquitin-specific protease
Molecular Function: protein binding
Biological Process: ubiquitin-dependent protein catabolic process
Reference #:  Q6ZTM0 (UniProtKB)
Alt. Names/Synonyms: bA137L10.3; bA137L10.4; C10orf29; FLJ37318; Inactive ubiquitin carboxyl-terminal hydrolase 54; Inactive ubiquitin-specific peptidase 54; ubiquitin specific peptidase 54; ubiquitin specific protease 54; ubiquitin specific proteinase 54; UBP54; USP54
Gene Symbols: USP54
Molecular weight: 187,388 Da
Basal Isoelectric point: 6.89  Predict pI for various phosphorylation states
Select Structure to View Below

USP54

Protein Structure Not Found.


STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 2 Y7-p _MSWKRNyFSGGrGS
0 2 R12-m1 RNyFSGGrGSVQGMF
0 1 S23 QGMFAPRSSTSIAPS
0 1 K105-u TLRSALAkTFQDEQR
0 1 S227 GDLRNCPSNCGERIR
0 8 S378-p YSRTCYDsEDsGREP
0 6 S381-p TCYDsEDsGREPSIS
0 11 T442-p SRDTGHLtDSECNQK
0 7 S481-p PQASGYHsEGETLKE
0 2 T485 GYHsEGETLKEKQAP
0 2 S603-p HCGYTQLsPFSEDSA
0 2 S632-p DIKFGGPsPQyKRWG
0 73 Y635-p FGGPsPQyKRWGPAR
0 3 S671-p SSERNSSsPVSLDAA
0 1 S674 RNSSsPVSLDAALPE
0 1 S854-p VDKKLQIsIRKARSL
0 9 Y1069-p AQPSLPLyRTCHPIM
0 2 Y1118-p DRGSEETyRPEFPST
0 3 S1189 PWAKQQSSLEGGDRP
0 5 Y1233-p RLAEPDIyQEkLSQV
0 1 K1236-u EPDIyQEkLSQVRDV
0 1 K1246-u QVRDVRSkDLGSSTD
0 1 S1362-p GMGRRLHsAHDPGLS
0 1 K1521-u GETSQGAkYTGRTLN
0 48 Y1529-p YTGRTLNyQsLPHRS
0 7 S1531-p GRTLNyQsLPHRSRT
0 2 S1645 PDDDWRQSSYASHSG
0 2 S1646 DDDWRQSSYASHSGH
0 2 Y1647 DDWRQSSYASHSGHR
0 2 S1649 WRQSSYASHSGHRRT
  USP54 iso10  
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- under review  
Y157 AQPSLPLYRTCHPIM
Y206 DRGSEETYRPEFPST
S277 PWAKQQSSLEGGDRP
Y321-p RLAEPDIyQEKLSQV
K324 EPDIyQEKLSQVRDV
K334 QVRDVRSKDLGSSTD
S450 GMGRRLHSAHDPGLS
K604 GETSQGAKYTGRTLN
Y612 YTGRTLNYQSLPHRS
S614 GRTLNYQSLPHRSRT
S728 PDDDWRQSSYASHSG
S729 DDDWRQSSYASHSGH
Y730 DDWRQSSYASHSGHR
S732 WRQSSYASHSGHRRT
  mouse

 
Y7 _MSWKRNYFSGSrGS
R12-m1 RNYFSGSrGSVQGMF
S23-p QGMFAPRsSMSIAPS
K105 TLRSALAKTFQDEQR
S227-p GDLRNCPsNCGERIR
S378-p YTKTCYDsEDsGHLt
S381-p TCYDsEDsGHLtDSE
T385-p sEDsGHLtDSECNQK
S424-p PQASGYHsEGEtLKE
T428-p GYHsEGEtLKEKQAP
R545 HCGYTQLRTFPEDAA
R574 DIKDGGSRSQHKLWG
H577 DGGSRSQHKLWGTAR
S613-p SSERNSSsPVsLDAA
S616-p RNSSsPVsLDAAPPD
S796 VDKKLQISIRKARSL
Y1018 AQPSIPPYSSCHPIT
Y1067 VRSSEEPYRLEFPST
S1138-p RWVKQPRsPDGRERP
Y1182 RLAEPDMYQGKLPQV
K1185 EPDMYQGKLPQVTDI
K1195 QVTDIRSKELGSSVN
S1312-p GMGRRLHsAPGLDLS
K1425 DETPQGVKYTGRTLN
Y1433 YTGRTLNYRSLPHRS
S1435 GRTLNYRSLPHRSRT
S1549-p PDDDWRQssyPsQDR
S1550-p DDDWRQssyPsQDRH
Y1551-p DDWRQssyPsQDRHR
S1553-p WRQssyPsQDRHRSP
  rat

 
Y7 _MSWKRNYFSGGRGS
R12 RNYFSGGRGSVQGMF
S23 QGMFAPRSSMSIAPS
K105 TLRSALAKTFQDEQR
S227 GDLRDCPSNCGERIR
S378 HTKTCYDSEDSGHLT
S381 TCYDSEDSGHLTDSE
T385 SEDSGHLTDSECNQK
S424 PQASGYHSEGETLKE
T428 GYHSEGETLKEKQAP
K545 HCGYTQLKTFPEDAA
S574 DIKDGGPSSQHKLWG
H577 DGGPSSQHKLWGTAR
S613 SSERNSSSPVSLDAA
S616 RNSSSPVSLDAAPPE
S796 VDKKLQISIRKARSL
Y1018 AQPAVPPYGACHPIM
Y1067 VRGSEEPYRPEFPST
- under review  
Y1182 RLAEADIYQGKLPQV
K1185 EADIYQGKLPQVTDT
- under review  
S1312 GMGRRLHSAPGLDLS
K1425 DETPQGVKYTGRTLN
Y1433 YTGRTLNYRSLPHRS
S1435 GRTLNYRSLPHRSRT
S1549 PDDDGRQSQYPSQYR
Q1550 DDDGRQSQYPSQYRH
Y1551 DDGRQSQYPSQYRHR
- under review  
Home  |  Curator Login With enhanced literature mining using Linguamatics I2E I2E Logo Produced by 3rd Millennium  |  Design by Digizyme
©2003-2013 Cell Signaling Technology, Inc.