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Protein Page:
K6c (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
K6c Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jul 2009]
Cellular Component: keratin filament; intermediate filament
Molecular Function: structural molecule activity
Reference #:  P48668 (UniProtKB)
Alt. Names/Synonyms: CK-6C; CK-6E; Cytokeratin-6C; Cytokeratin-6E; K2C6C; K6C; K6E; keratin 6C; keratin 6E; Keratin K6h; Keratin, type II cytoskeletal 6C; Keratin-6C; KRT6C; KRT6E; MGC102925; MGC163455; MGC163457; Type-II keratin Kb12
Gene Symbols: KRT6C
Molecular weight: 60,025 Da
Basal Isoelectric point: 8.09  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

K6c

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 2 S22-p RRGFSANsARLPGVS
2 38 S60-p GAGFGSRsLyGLGGS
0 188 Y62-p GFGSRsLyGLGGSKR
0 142 Y83-p SCAISGGyGSRAGGS
0 3 K168-u AEEREQIkTLNNkFA
1 29 K173-a QIkTLNNkFAsFIDk
0 8 K173-u QIkTLNNkFAsFIDk
0 16 S176-p TLNNkFAsFIDkVRF
0 6 K180-a kFAsFIDkVRFLEQQ
0 8 K180-u kFAsFIDkVRFLEQQ
0 54 Y278-p KKDVDAAyMNKVELQ
0 92 Y341-p IAEVKAQyEEIAQRS
0 9 Y356-p RAEAESWyQTKyEEL
0 42 Y360-p ESWyQTKyEELQVTA
0 4 Y551-p GGSSTIKyTTTSSSS
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