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Protein Page:
PEX5L (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
g O-GlcNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
PEX5L Belongs to the peroxisomal targeting signal receptor family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Cellular Component: peroxisomal membrane; perinuclear region of cytoplasm; dendrite; intracellular cyclic nucleotide activated cation channel complex; cytosol
Molecular Function: small GTPase binding; peroxisome targeting sequence binding; peroxisome matrix targeting signal-1 binding; intracellular cyclic nucleotide activated cation channel activity; Rab GTPase binding
Biological Process: maintenance of protein localization; regulated secretory pathway; regulation of membrane potential; protein import into peroxisome matrix; positive regulation of adrenocorticotropic hormone secretion
Reference #:  Q8IYB4 (UniProtKB)
Alt. Names/Synonyms: Peroxin-5-related protein; peroxisomal biogenesis factor 5-like; Peroxisome biogenesis factor 5-like; PEX2-related protein; PEX5-like protein; PEX5-related protein; PEX5L; Pex5p-related protein; PEX5R; Pex5Rp; PXR2; PXR2B
Gene Symbols: PEX5L
Molecular weight: 69,697 Da
Basal Isoelectric point: 5.18  Predict pI for various phosphorylation states
Select Structure to View Below

PEX5L
Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

 
0 1 S79 QESRPLLSPSIDDFL
0 1 T99-p EAIARPVtSNTAVLt
0 1 T106-p tSNTAVLtTGLDLLD
0 1 S115-p GLDLLDLsEPVSQTQ
0 1 T123-p EPVSQTQtKAKKSEP
0 1 S128 TQtKAKKSEPSSKTS
0 1 S131 KAKKSEPSSKTSSLK
0 1 S198-p HPMAERKsSsSRTGs
0 1 S200-p MAERKsSsSRTGsKE
0 1 T203 RKsSsSRTGsKELLW
0 3 S205-p sSsSRTGsKELLWSS
0 3 S216 LWSSEHRSQPELSGG
0 4 S253 TKEHRWGSALLsRNH
0 4 S257-p RWGSALLsRNHsLEE
0 20 S261-p ALLsRNHsLEEEFER
0 1 K335 GAFEEGLKRLKEGDL
0 1 S437 LVKSKKGSPGLTRRM
0 2 S445 PGLTRRMSKsPVDSS
0 7 S447-p LTRRMSKsPVDSSVL
0 1 S452 SKsPVDSSVLEGVKE
  mouse

► Hide Isoforms 		 
S20-p QESRPLLsPSIDDFL
T40 EAIAKPVTSNTAVLT
T47 TSNTAVLTTGLDLLD
S56 GLDLLDLSEPVSQPQ
T64 EPVSQPQTKAKKsEP
S69-p PQTKAKKsEPsSKSS
S72-p KAKKsEPsSKSSSLK
S139-p HLMAERKsCsSRtGs
S141-p MAERKsCsSRtGsKE
T144-p RKsCsSRtGsKELLW
S146-p sCsSRtGsKELLWSA
S157-p LWSAEHRsQPELSTG
S194-p TKEHRWGsALLsRNH
S198-p RWGsALLsRNHsLEE
S202-p ALLsRNHsLEEEFER
K276 GAFEEGLKRLKEGDL
S378-p LVKNKKGsPGLTRRM
S386-p PGLTRRMsKsPVDSs
S388-p LTRRMsKsPVDSsVL
S393-p sKsPVDSsVLEGVKE
  PEX5L iso3  
S68 QESRPLLSPSIDDFL
T88 EAIAKPVTSNTAVLT
T95 TSNTAVLTTGLDLLD
S104 GLDLLDLSEPVSQPQ
T112 EPVSQPQTKAKKSEP
S117 PQTKAKKSEPSSKSS
S120 KAKKSEPSSKSSSLK
S187 HLMAERKSCSSRTGS
S189 MAERKSCSSRTGSKE
T192 RKSCSSRTGSKELLW
S194 SCSSRTGSKELLWSA
S205 LWSAEHRSQPELSTG
S242 TKEHRWGSALLSRNH
S246 RWGSALLSRNHSLEE
S250 ALLSRNHSLEEEFER
K324 GAFEEGLKRLKEGDL
S426 LVKNKKGSPGLTRRM
S434 PGLTRRMSKSPVDSS
S436 LTRRMSKSPVDSSVL
S441 SKSPVDSSVLEGVKE
  rat

 
S55 QESRPLLSPSIDDFL
T75 EAIAKPVTSNTAVLT
T82 TSNTAVLTTGLDLLD
S91 GLDLLDLSEPVSQTQ
T99 EPVSQTQTKAKKSES
S104 TQTKAKKSESSSKSS
S107 KAKKSESSSKSSSLK
S174 HLMAERKSCSSRAGS
S176 MAERKSCSSRAGSKE
A179 RKSCSSRAGSKELLW
S181 SCSSRAGSKELLWSS
S192 LWSSEHRSQPELSTG
S229 TKEHRWGSALLSRNH
S233 RWGSALLSRNHSLEE
S237 ALLSRNHSLEEEFER
K311-u GAFEEGLkRLKEGDL
S413 LVKNKKGSPGLTRRM
S421 PGLTRRMSKSPVDSS
S423 LTRRMSKSPVDSSVL
S428 SKSPVDSSVLEGVKD
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