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Protein Page:
SEMA4B (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
SEMA4B a single-pass type I membrane protein that inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. Two alternatively spliced human isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Cell surface
Cellular Component: integral to membrane
Molecular Function: receptor activity
Biological Process: nervous system development; cell differentiation
Reference #:  J3KNP4 (UniProtKB)
Alt. Names/Synonyms: KIAA1745; MGC131831; SEM4B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4B; SEMA4B; SEMAC; Semaphorin-4B; SemC
Gene Symbols: SEMA4B
Molecular weight: 92,766 Da
Basal Isoelectric point: 6.64  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

SEMA4B

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K745-u YRHRNSMkVFLKQGE
0 5 T780-p NGLGPPStPLDHRGy
0 9 Y787-p tPLDHRGyQSLSDsP
0 3 S793-p GyQSLSDsPPGSRVF
0 5 P794 yQSLSDsPPGSRVFt
0 2 T801-p PPGSRVFtESEKRPL
0 54 S809-p ESEKRPLsIQDsFVE
0 19 S813-p RPLsIQDsFVEVsPV
0 129 S818-p QDsFVEVsPVCPRPR
0 344 S830-p RPRVRLGsEIRDsVV
0 3 S835-p LGsEIRDsVV_____
5622 : Phospho-Semaphorin 4B (Ser825) Antibody
  mouse

 
K731 YRHRDGMKLFLKQGE
T766-p NGVGPPStPLDHRGy
Y773-p tPLDHRGyQALSDSs
S779 GyQALSDSsPGPRVF
S780-p yQALSDSsPGPRVFT
T787 sPGPRVFTESEKRPL
S795-p ESEKRPLsIQDsFVE
S799-p RPLsIQDsFVEVsPV
S804-p QDsFVEVsPVCPRPR
S816-p RPRVRLGsEIRDSVV
S821 LGsEIRDSVV_____
5622 : Phospho-Semaphorin 4B (Ser825) Antibody
  rat

 
K729 YRNRDGMKLFLKQGE
T764 NGVGPPSTPLDHRGY
Y771 TPLDHRGYQALSDSS
S777 GYQALSDSSPGPRVF
S778 YQALSDSSPGPRVFT
T785 SPGPRVFTESEKRPL
S793 ESEKRPLSIQDSFVE
S797 RPLSIQDSFVEVSPV
S802 QDSFVEVSPVCPRPR
S814 RPRVRLGSEIRDSVV
S819 LGSEIRDSVV_____
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