May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Note: This description may include information from UniProtKB.
Protein type: Protein phosphatase, tyrosine (non-receptor); Motility/polarity/chemotaxis; EC 188.8.131.52
Cellular Component: cytoplasm; cytoplasmic membrane-bound vesicle; early endosome; nucleus; endosome
Molecular Function: protein binding; protein tyrosine phosphatase activity
Biological Process: protein transport; ubiquitin-dependent protein catabolic process via the multivesicular body pathway; regulation of cell migration
Alt. Names/Synonyms: DKFZp564F0923; HD-PTP; HDPTP; His domain-containing protein tyrosine phosphatase; His-domain protein tyrosine phosphatase; KIAA1471; Protein tyrosine phosphatase TD14; protein tyrosine phosphatase, non-receptor type 23; PTN23; PTP-TD14; PTPN23; Tyrosine-protein phosphatase non-receptor type 23
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.