a transcription factor of the MADS domain family that binds to the serum response element (SRE). Regulates the transcription of immediate early genes including c-fos. Binds DNA as a multimer, probably a dimer. Note: This description may include information from UniProtKB.
Protein type: Transcription factor; Motility/polarity/chemotaxis
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; protein homodimerization activity; chromatin DNA binding; transcription factor activity; transcription factor binding
Biological Process: transcription from RNA polymerase II promoter; developmental growth; erythrocyte development; positive regulation of transcription by glucose; response to toxin; heart development; cell-matrix adhesion; response to hormone stimulus; neuron migration; cardiac myofibril assembly; muscle maintenance; negative regulation of cell proliferation; tangential migration from the subventricular zone to the olfactory bulb; regulation of smooth muscle cell differentiation; morphogenesis of an epithelial sheet; heart looping; positive regulation of smooth muscle contraction; negative regulation of cell migration; neurite development; associative learning; positive thymic T cell selection; regulation of cell adhesion; positive regulation of filopodium formation; platelet activation; skin morphogenesis; hippocampus development; sarcomere organization; angiogenesis involved in wound healing; mRNA transcription from RNA polymerase II promoter; trophectodermal cell differentiation; regulation of water loss via skin; patterning of blood vessels; contractile actin filament bundle formation; long-term memory; cell migration during sprouting angiogenesis; mesoderm formation; response to cytokine stimulus; stress fiber formation; response to hypoxia; neuron development; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; platelet formation; positive regulation of cell differentiation
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.