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Protein Page:
Oct11 (human)

Overview
Oct11 Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Regulated the expression of a number of genes such as SPRR2A or placental lactogen. Belongs to the POU transcription factor family. Class- 2 subfamily. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA binding protein; Transcription factor
Cellular Component: transcription factor complex; cytoplasm; nucleolus; nucleus
Molecular Function: protein dimerization activity; protein binding; sequence-specific DNA binding
Biological Process: regulation of transcription from RNA polymerase II promoter; keratinocyte differentiation; epidermis development; transcription, DNA-dependent; wound healing; positive regulation of transcription from RNA polymerase II promoter
Reference #:  Q9UKI9 (UniProtKB)
Alt. Names/Synonyms: Epoc-1; FLJ40063; MGC126698; Oct-11; OCT11; Octamer-binding protein 11; Octamer-binding transcription factor 11; OTF-11; OTF11; PLA-1; PLA1; PO2F3; POU class 2 homeobox 3; POU domain, class 2, transcription factor 3; POU transcription factor; POU2F3; Skn-1a; Transcription factor PLA-1; Transcription factor Skn-1
Gene Symbols: POU2F3
Molecular weight: 47,432 Da
Basal Isoelectric point: 8.66  Predict pI for various phosphorylation states
Select Structure to View Below

Oct11

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S14-p MHTDIKMsGDVADst
0 1 S20-p MsGDVADstDARSTL
0 1 T21-p sGDVADstDARSTLS
0 1 S25 ADstDARSTLSQVEP
0 1 T26 DstDARSTLSQVEPG
0 8 S238-p RFEALNLsFKNMCKL
0 1 S258-p KWLNDAEssPSDPSV
0 1 S259-p WLNDAEssPSDPSVS
0 6 S287-p RKRKKRTsIETNIRL
  mouse

 
S14 MHTEIKMSGDVADST
S20 MSGDVADSTDTRstF
T21 SGDVADSTDTRstFG
S25-p ADSTDTRstFGQVEP
T26-p DSTDTRstFGQVEPG
S231 RFEALNLSFKNMCKL
S251 KWLNDPESSPSDPSA
S252 WLNDPESSPSDPSAS
S280 RKRKKRTSIETNIRL
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