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Protein Page:
RRas (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
RRas a small G protein of the Ras family. Promotes focal adhesion formation by signaling to FAK and p130(Cas). Promotes tumor growth of cervical epithelial cells and increases their migration potential over collagen through a pathway that involves PI 3-K. Note: This description may include information from UniProtKB.
Protein type: G protein, monomeric; Motility/polarity/chemotaxis; G protein; G protein, monomeric, Ras
Cellular Component: plasma membrane
Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; protein complex binding
Biological Process: synaptic transmission; axon guidance; positive regulation of angiogenesis; GTP catabolic process; Ras protein signal transduction; negative regulation of cell migration
Reference #:  P10301 (UniProtKB)
Alt. Names/Synonyms: Oncogene RRAS; p23; Ras-related protein R-Ras; related RAS viral (r-ras) oncogene homolog; RRAS
Gene Symbols: RRAS
Molecular weight: 23,480 Da
Basal Isoelectric point: 6.44  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics  |  Angiogenesis  |  B Cell Receptor Signaling  |  ErbB/HER Signaling  |  ESC Pluripotency and Differentiation  |  GPCR Signaling to MAPKs  |  Growth And Differentiation Control by MAPKs  |  IL6 Signaling  |  Inhibition of Apoptosis  |  Insulin Receptor Signaling  |  NF-kB Signaling  |  SAPK/JNK Signaling Cascades  |  T Cell Receptor Signaling  |  TGF-├č Signaling  |  Warburg Effect
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

RRas

Protein Structure Not Found.


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Sites Implicated In
cell adhesion, altered: Y66‑p
cell motility, altered: Y66‑p
cytoskeletal reorganization: Y66‑p
molecular association, regulation: Y66‑p

Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T9-p SSGAASGtGRGRPRG
0 3 Y58-p QSYFVSDyDPTIEDS
3 0 Y66-p DPTIEDSyTKICSVD
0 1 S155 SQRQVPRSEASAFGA
0 2 K192-ub QLVRAVRkYQEQELP
0 5 S201-p QEQELPPsPPsAPRK
0 2 S204-p ELPPsPPsAPRKKGG
  mouse

 
T9 SSGAASGTGRGRPRG
Y58 QSYFVSDYDPTIEDS
Y66 DPTIEDSYTKICTVD
S155-p NQRQVLRsEASSFSA
K192-ub QLVRAVRkYQEQELP
S201-p QEQELPPsPPSAPRK
S204 ELPPsPPSAPRKKDG
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