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Protein Page:
REM1 (human)

Overview
REM1 Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling. Belongs to the small GTPase superfamily. RGK family. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric, RGK; G protein, monomeric
Chromosomal Location of Human Ortholog: 20q11.21
Cellular Component: membrane
Molecular Function: calmodulin binding; GTP binding
Biological Process: GTP catabolic process; small GTPase mediated signal transduction
Reference #:  O75628 (UniProtKB)
Alt. Names/Synonyms: GD:REM; GES; GTP-binding protein REM 1; GTPase GES; GTPase-regulating endothelial cell sprouting; MGC48669; Rad and Gem-like GTP-binding protein 1; RAS (RAD and GEM)-like GTP-binding 1; REM; REM1
Gene Symbols: REM1
Molecular weight: 32,947 Da
Basal Isoelectric point: 9.02  Predict pI for various phosphorylation states
Select Structure to View Below

REM1

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
1 8 S18-p TPLHRRAsTPLPLSP
0 2 T19 PLHRRAsTPLPLSPR
0 2 S24 AsTPLPLSPRGHQPG
0 5 S51 PRLGQSASLNPPTQK
0 1 S168-p YSIADRGsFEsASEL
0 1 S171-p ADRGsFEsASELRIQ
0 1 S250-p LRLRRRDsAAKEPPA
0 1 P255 RDsAAKEPPAPRRPA
0 1 A257 sAAKEPPAPRRPASL
1 0 S263 PAPRRPASLAQRARR
1 0 S289 RRALKARSKSCHNLA
0 2 S291 ALKARSKSCHNLAVL
  mouse

 
S18-p TTLRRRAstPLPLsS
T19-p TLRRRAstPLPLsSR
S24-p AstPLPLsSRGHQPG
S51-p PRLGQSVsLNPPVRK
S167 YSIADRSSFESASEL
S170 ADRSSFESASELRIQ
N249 LRLRRQDNAAPEtPs
T254-p QDNAAPEtPsPRRRA
S256-p NAAPEtPsPRRRAsL
S262-p PsPRRRAsLGQRARR
S288-p RRALKARsKsCHNLA
S290-p ALKARsKsCHNLAVL
  rat

 
S18 TTLRRRASTPLPLSS
T19 TLRRRASTPLPLSSR
S24 ASTPLPLSSRGHQPG
S51-p PRLGQSAsLNPPIRK
S167 YSIADRSSFESASEL
S170 ADRSSFESASELRIQ
N249 LRLRRQDNAAPETPS
T254 QDNAAPETPSPRRRA
S256 NAAPETPSPRRRASL
S262 PSPRRRASLGQRARR
S288 RRALKARSKSCHNLA
S290 ALKARSKSCHNLAVL
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