a non-receptor protein-tyrosine phosphatase. STEP (striatum enriched phosphatase) Contains a single phosphatase catalytic domain located at the C-terminus. Two alternatively-spliced messages have been described. Note: This description may include information from UniProtKB.
Protein type: EC 188.8.131.52; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Protein phosphatase, tyrosine (non-receptor)
Chromosomal Location of Human Ortholog: 11p15.1
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: phosphotyrosine binding; protein tyrosine phosphatase activity
Biological Process: protein amino acid dephosphorylation
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.