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Protein Page:
POLRMT (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
POLRMT DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.7.6; Transferase; Mitochondrial; Transcription initiation complex
Cellular Component: mitochondrion; mitochondrial matrix
Molecular Function: protein binding; DNA binding; DNA-directed RNA polymerase activity
Biological Process: gene expression; transcription from mitochondrial promoter; transcription initiation from mitochondrial promoter
Reference #:  O00411 (UniProtKB)
Alt. Names/Synonyms: APOLMT; DNA-directed RNA polymerase, mitochondrial; h-mtRPOL; MTRNAP; MtRPOL; POLRMT; polymerase (RNA) mitochondrial (DNA directed); RPOM
Gene Symbols: POLRMT
Molecular weight: 138,620 Da
Basal Isoelectric point: 9.19  Predict pI for various phosphorylation states
Select Structure to View Below

POLRMT

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K28-m1 GRPGLPGkEGTAGGV
0 1 S77-p VRQLQAEsVSEVVVN
0 2 T315-p RQDQDAGtIERCLEQ
0 1 T436-p HARKTLKtLRDQWEK
0 3 Y999-p QTVMTVVyGVTRYGG
0 1 K1197-u RFCSEPQkILEASQL
  mouse

 
- gap
- gap
T287 RRDQDVRTIQRCLKQ
- gap
Y970 QTVMTVVYGVTRYGG
K1168 FCSVSSIKSLKSSER
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