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MAP2 (human)

Overview MAP2 a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported. Note: This description may include information from UniProtKB. Protein type: Cytoskeletal protein; Motility/polarity/chemotaxis Cellular Component: microtubule; microtubule associated complex; cell soma; cytoplasm; dendritic shaft Molecular Function: calmodulin binding; tubulin binding; protein binding; structural molecule activity Biological Process: axonogenesis; dendrite morphogenesis; peptidyl-threonine phosphorylation; neurite development; microtubule bundle formation; central nervous system neuron development Reference #:  P11137 (UniProtKB) Alt. Names/Synonyms: DKFZp686I2148; MAP-2; MAP2; MAP2A; MAP2B; MAP2C; Microtubule-associated protein 2 Gene Symbols: MAP2 Molecular weight: 199,526 Da Basal Isoelectric point: 4.82  Predict pI for various phosphorylation states Protein-Specific Antibodies or siRNAs from Cell Signaling Technology®

Select Structure to View Below MAP2

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	Sites Implicated In
cytoskeletal reorganization: S1679‑p, S1710‑p, S1782‑p intracellular localization: S1679‑p, S1710‑p, S1782‑p molecular association, regulation: Y67‑p, S1679‑p, S1710‑p, S1782‑p

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human ► Hide Isoforms
0	14		P28	EASAHSHPPEIKDQG
1	0		Y50	RSANGFPYREDEEGA
0	2		S63-p	GAFGEHGsQGtySNT
0	1		T66-p	GEHGsQGtySNTKEN
2	0		Y67-p	EHGsQGtySNTKENG
0	1		T130	LPLAAEETANLPPSP
1	2		S136	ETANLPPSPPPSPAS
0	3		S140	LPPSPPPSPASEQTV
0	3		S143	SPPPSPASEQTVTVE
0	2		T146	PSPASEQTVTVEEDL
0	1		T148	PASEQTVTVEEDLLT
0	1		K220	MQGTEEEKAPLALFG
0	15		S285-p	WGLVAPIsPGPLtPM
0	10		T290-p	PIsPGPLtPMREKDV
0	2		S315-p	QFDSPMPsPFQGGSF
0	1		S321	PsPFQGGSFtLPLDV
0	1		T323-p	PFQGGSFtLPLDVMK
0	1		K330	tLPLDVMKNEIVTET
0	1		T335	VMKNEIVTETSPFAP
0	1		F366	PATAKDSFKIEEPHE
0	6		S451	LEEKTTISDKEAVPK
0	1		T480	IQTSTEHTFSEQKDQ
0	1		S498	TDMLKQDSFPVSLEQ
0	1		T516-p	DSAMTSKtLEKAMTE
0	3		T522	KtLEKAMTEPSALIE
0	1		A552	DKIEGVGAATSAELD
0	1		K579	YFETSALKEEATKSI
0	1		S585	LKEEATKSIEPGSDy
0	1		I586	KEEATKSIEPGSDyY
0	6		Y592-p	SIEPGSDyYELSDTR
0	1		S596	GSDyYELSDTRESVH
0	1		T598	DyYELSDTRESVHES
0	1		S601	ELSDTRESVHESIDT
0	2		S605	TRESVHESIDTMSPM
0	2		T608	SVHESIDTMSPMHKN
0	9		S610	HESIDTMSPMHKNGD
0	3		S629	TGKESQPSPPAQEAG
0	1		S653	SDLPEEPSSPQERMF
0	4		S654	DLPEEPSSPQERMFT
0	1		S684	NKDDLTLSRSLGLGG
0	2		S725	FGRGHDLSPLASDIL
0	1		S729	HDLSPLASDILTNTS
0	1		T733	PLASDILTNTSGSMD
0	2		T735	ASDILTNTSGSMDEG
0	2		S736	SDILTNTSGSMDEGD
0	3		S738	ILTNTSGSMDEGDDY
0	2		Y745	SMDEGDDYLPATTPA
0	1		T775	QIEKVKATGEESTQA
0	1		K793	CESPFLAKDFYKNGT
0	1		S817-p	LDLAGTRsRLAsVsA
0	49		S821-p	GTRsRLAsVsADAEV
0	3		S823-p	RsRLAsVsADAEVAR
0	3		S833-p	AEVARRKsVPSETVV
0	1		S843-p	SETVVEDsRTGLPPV
0	1		I857	VTDENHVIVKtDsQL
0	1		T860-p	ENHVIVKtDsQLEDL
0	1		S862-p	HVIVKtDsQLEDLGY
0	3		K903	FYEGTDDKVRRDLAT
0	2		S913	RDLATDLSLIEVKLA
0	6		K918	DLSLIEVKLAAAGRV
0	3		S936	FSVDKEASAHISGDK
0	1		A1010	DLSIPTDASSEKAEK
0	5		S1011	LSIPTDASSEKAEKG
0	2		A1015	TDASSEKAEKGLSSV
0	1		K1017	ASSEKAEKGLSSVPE
0	1		S1020	EKAEKGLSSVPEIAE
0	2		S1021	KAEKGLSSVPEIAEV
0	1		S1031	EIAEVEPSKKVEQGL
0	1		K1032	IAEVEPSKKVEQGLD
0	1		K1033	AEVEPSKKVEQGLDF
0	1		Q1043	QGLDFAVQGQLDVKI
0	1		S1106-p	MKEGTKVsEtEVKEK
0	2		T1108-p	EGTKVsEtEVKEKVA
0	1		S1130	EAVDKEESYESSGEH
0	1		Y1131	AVDKEESYESSGEHE
0	1		S1133	DKEESYESSGEHESL
0	1		S1134	KEESYESSGEHESLT
0	1		S1139	ESSGEHESLTMESLK
0	1		S1144	HESLTMESLKADEGK
0	1		K1151	SLKADEGKKEtsPEs
0	1		K1152	LKADEGKKEtsPEsS
0	7		T1154-p	ADEGKKEtsPEsSLI
0	10		S1155-p	DEGKKEtsPEsSLIQ
0	3		S1158-p	KKEtsPEsSLIQDEI
0	3		S1159	KEtsPEsSLIQDEIA
0	2		S1234-p	SEPAEIQsEEEEIEA
0	1		S1252	YDKLLFRSDTLQITD
0	1		T1254	KLLFRSDTLQITDLG
0	1		S1324-p	PEVERRPsPHDEEEF
0	18		S1347-p	QAEPKDGsPEAPAsP
0	18		S1353-p	GsPEAPAsPEREEVA
0	1		S1362	EREEVALSEYKtEty
0	1		T1366-p	VALSEYKtEtyDDYK
0	1		T1368-p	LSEYKtEtyDDYKDE
0	1		Y1369-p	SEYKtEtyDDYKDET
0	1		S1421	EKEARRSSLEKHRkE
0	1		K1427-a	SSLEKHRkEKPFKTG
0	2		S1439	KTGRGRIStPERKVA
0	10		T1440-p	TGRGRIStPERKVAK
0	1		K1448	PERKVAKKEPSTVSR
0	6		S1480-p	KTEVQAHsPSRKFIL
0	1		S1482	EVQAHsPSRKFILKP
0	6		K1488	PSRKFILKPAIKYtR
0	1		T1494-p	LKPAIKYtRPtHLsC
0	1		T1497-p	AIKYtRPtHLsCVKR
0	1		S1500-p	YtRPtHLsCVKRkTT
0	2		K1503	PtHLsCVKRkTTAAG
0	1		K1505-a	HLsCVKRkTTAAGGE
0	1		T1506	LsCVKRkTTAAGGES
0	1		T1507	sCVKRkTTAAGGESA
0	1		G1510	KRkTTAAGGESALAP
0	1		K1521	ALAPSVFKQAkDKVS
0	1		K1524-a	PSVFKQAkDKVSDGV
0	1		-	gap
0	5		-	gap
0	1		-	gap
0	1		S1528	KQAkDKVSDGVtKsP
0	1		T1532-p	DKVSDGVtKsPEKRs
0	14		S1534-p	VSDGVtKsPEKRssL
0	3		S1539-p	tKsPEKRssLPRPSS
0	4		S1540-p	KsPEKRssLPRPSSI
0	2		S1555	LPPRRGVSGDRDENS
0	1		S1564-p	DRDENSFsLNSSISS
1	0		T1577	SSSARRTTRSEPIRR
0	12		S1588-p	PIRRAGKsGtstPtt
0	7		T1590-p	RRAGKsGtstPttPG
0	9		S1591-p	RAGKsGtstPttPGs
0	17		T1592-p	AGKsGtstPttPGst
0	15		T1594-p	KsGtstPttPGstAI
0	9		T1595-p	sGtstPttPGstAIt
0	7		S1598-p	stPttPGstAItPGt
0	11		T1599-p	tPttPGstAItPGtP
0	13		T1602-p	tPGstAItPGtPPsy
0	36		T1605-p	stAItPGtPPsysSR
0	9		S1608-p	ItPGtPPsysSRtPG
0	7		Y1609-p	tPGtPPsysSRtPGt
0	5		S1610-p	PGtPPsysSRtPGtP
0	5		S1611	GtPPsysSRtPGtPG
0	9		T1613-p	PPsysSRtPGtPGtP
2	14		T1616-p	ysSRtPGtPGtPsYP
2	24		T1619-p	RtPGtPGtPsYPRTP
0	6		S1621-p	PGtPGtPsYPRTPHt
0	22		Y1622	GtPGtPsYPRTPHtP
0	9		T1628-p	sYPRTPHtPGtPKSA
0	10		T1631-p	RTPHtPGtPKSAILV
0	3		S1634	HtPGtPKSAILVPSE
0	25		T1649-p	KKVAIIRtPPKsPAt
0	20		S1653-p	IIRtPPKsPAtPKQL
0	18		T1656-p	tPPKsPAtPKQLRLI
2	2		S1679-p	NVKSKIGsTDNIKYQ
0	1		-	gap
0	1		T1696	GGQVQIVTKKIDLsH
0	2		K1697	GQVQIVTKKIDLsHV
0	1		S1702-p	VTKKIDLsHVTsKCG
0	2		S1706-p	IDLsHVTsKCGsLKN
2	0		S1710-p	HVTsKCGsLKNIRHR
0	10		T1780-p	DHGAEIItQsPGRss
1	39		S1782-p	GAEIItQsPGRssVA
0	9		G1784	EIItQsPGRssVAsP
0	10		S1786-p	ItQsPGRssVAsPRR
0	10		S1787-p	tQsPGRssVAsPRRL
0	20		S1790-p	PGRssVAsPRRLsNV
0	9		S1795-p	VAsPRRLsNVsssGs
0	2		S1798-p	PRRLsNVsssGsINL
0	3		S1799-p	RRLsNVsssGsINLL
0	2		S1800-p	RLsNVsssGsINLLE
0	2		S1802-p	sNVsssGsINLLESP
0	4		S1808	GsINLLESPQLAtLA
0	1		T1813-p	LESPQLAtLAEDVtA
0	1		T1819-p	AtLAEDVtAALAKQG

	MAP2 iso2
P28	EASAHSHPPEIKDQG
Y50	RSANGFPYREDEEGA
S63	GAFGEHGSQGTySNT
T66	GEHGSQGTySNTKEN
Y67-p	EHGSQGTySNTKENG
T130	LPLAAEETANLPPSP
S136	ETANLPPSPPPSPAS
S140	LPPSPPPSPASEQTV
S143	SPPPSPASEQTVTVE
T146	PSPASEQTVTVEEAA
T148	PASEQTVTVEEAAGG
-	gap
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-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
-	gap
G154	VTVEEAAGGESALAP
K165	ALAPSVFKQAKDKVS
K168	PSVFKQAKDKVSDGV
-	gap
-	gap
-	gap
S172	KQAKDKVSDGVTKSP
T176	DKVSDGVTKSPEKRS
S178	VSDGVTKSPEKRSSL
S183	TKSPEKRSSLPRPSS
S184	KSPEKRSSLPRPSSI
S199	LPPRRGVSGDRDENS
S208	DRDENSFSLNSSISS
T221	SSSARRTTRSEPIRR
S232	PIRRAGKSGTStPTT
T234	RRAGKSGTStPTTPG
S235	RAGKSGTStPTTPGS
T236-p	AGKSGTStPTTPGST
T238	KSGTStPTTPGSTAI
T239	SGTStPTTPGSTAIT
S242	StPTTPGSTAITPGT
T243	tPTTPGSTAITPGTP
T246	TPGSTAITPGTPPSY
T249	STAITPGTPPSYSSR
S252	ITPGTPPSYSSRTPG
Y253	TPGTPPSYSSRTPGT
S254	PGTPPSYSSRTPGTP
S255	GTPPSYSSRTPGTPG
T257	PPSYSSRTPGTPGTP
T260	YSSRTPGTPGTPSYP
T263	RTPGTPGTPSYPRTP
S265	PGTPGTPSYPRTPHT
Y266	GTPGTPSYPRTPHTP
T272	SYPRTPHTPGTPKSA
T275	RTPHTPGTPKSAILV
S278	HTPGTPKSAILVPSE
T293	KKVAIIRTPPKSPAT
S297	IIRTPPKSPATPKQL
T300	TPPKSPATPKQLRLI
S323	NVKSKIGSTDNIKYQ
-	gap
T340	GGQVQIVTKKIDLSH
K341	GQVQIVTKKIDLSHV
S346	VTKKIDLSHVTSKCG
S350	IDLSHVTSKCGSLKN
S354	HVTSKCGSLKNIRHR
T424	DHGAEIITQSPGRSS
S426	GAEIITQSPGRSSVA
G428	EIITQSPGRSSVASP
S430	ITQSPGRSSVASPRR
S431	TQSPGRSSVASPRRL
S434	PGRSSVASPRRLSNV
S439	VASPRRLSNVSSSGS
S442	PRRLSNVSSSGSINL
S443	RRLSNVSSSGSINLL
S444	RLSNVSSSGSINLLE
S446	SNVSSSGSINLLESP
S452	GSINLLESPQLATLA
T457	LESPQLATLAEDVTA
T463	ATLAEDVTAALAKQG

	MAP2 iso3
P28	EASAHSHPPEIKDQG
Y50-p	RSANGFPyREDEEGA
S63	GAFGEHGSQGTySNT
T66	GEHGSQGTySNTKEN
Y67-p	EHGSQGTySNTKENG
T130	LPLAAEETANLPPSP
S136	ETANLPPSPPPSPAS
S140	LPPSPPPSPASEQTV
S143	SPPPSPASEQTVTVE
T146	PSPASEQTVTVEEAS
T148	PASEQTVTVEEASKM
K216	MQGTEEEKAPLALFG
S281	WGLVAPISPGPLtPM
T286-p	PISPGPLtPMREKDV
S311	QFDSPMPSPFQGGSF
S317	PSPFQGGSFTLPLDV
T319	PFQGGSFTLPLDVMK
K326	TLPLDVMKNEIVTET
T331	VMKNEIVTETSPFAP
F362	PATAKDSFKIEEPHE
S447	LEEKTTISDKEAVPK
T476	IQTSTEHTFSEQKDQ
S494	TDMLKQDSFPVSLEQ
T512	DSAMTSKTLEKAMTE
T518	KTLEKAMTEPSALIE
A548	DKIEGVGAATSAELD
K575	YFETSALKEEATKSI
S581	LKEEATKSIEPGSDY
I582	KEEATKSIEPGSDYY
Y588	SIEPGSDYYELSDTR
S592	GSDYYELSDTRESVH
T594	DYYELSDTRESVHES
S597	ELSDTRESVHESIDT
S601	TRESVHESIDTMSPM
T604	SVHESIDTMSPMHKN
S606	HESIDTMSPMHKNGD
S625	TGKESQPSPPAQEAG
S649	SDLPEEPSSPQERMF
S650	DLPEEPSSPQERMFT
S680	NKDDLTLSRSLGLGG
S721	FGRGHDLSPLASDIL
S725	HDLSPLASDILTNTS
T729	PLASDILTNTSGSMD
T731	ASDILTNTSGSMDEG
S732	SDILTNTSGSMDEGD
S734	ILTNTSGSMDEGDDY
Y741	SMDEGDDYLPATTPA
T771	QIEKVKATGEESTQA
K789	CESPFLAKDFYKNGT
S813	LDLAGTRSRLAsVsA
S817-p	GTRSRLAsVsADAEV
S819-p	RSRLAsVsADAEVAR
S829	AEVARRKSVPSETVV
S839	SETVVEDSRTGLPPV
I853	VTDENHVIVKTDSQL
T856	ENHVIVKTDSQLEDL
S858	HVIVKTDSQLEDLGY
K899	FYEGTDDKVRRDLAT
S909	RDLATDLSLIEVKLA
K914	DLSLIEVKLAAAGRV
S932	FSVDKEASAHISGDK
A1006	DLSIPTDASSEKAEK
S1007	LSIPTDASSEKAEKG
A1011	TDASSEKAEKGLSSV
K1013	ASSEKAEKGLSSVPE
S1016	EKAEKGLSSVPEIAE
S1017	KAEKGLSSVPEIAEV
S1027	EIAEVEPSKKVEQGL
K1028	IAEVEPSKKVEQGLD
K1029	AEVEPSKKVEQGLDF
Q1039	QGLDFAVQGQLDVKI
S1102	MKEGTKVSETEVKEK
T1104	EGTKVSETEVKEKVA
S1126	EAVDKEESYESSGEH
Y1127	AVDKEESYESSGEHE
S1129	DKEESYESSGEHESL
S1130	KEESYESSGEHESLT
S1135	ESSGEHESLTMESLK
S1140	HESLTMESLKADEGK
K1147	SLKADEGKKETSPES
K1148	LKADEGKKETSPESS
T1150	ADEGKKETSPESSLI
S1151	DEGKKETSPESSLIQ
S1154	KKETSPESSLIQDEI
S1155	KETSPESSLIQDEIA
S1230	SEPAEIQSEEEEIEA
S1248	YDKLLFRSDTLQITD
T1250	KLLFRSDTLQITDLG
S1320	PEVERRPSPHDEEEF
S1343	QAEPKDGSPEAPASP
S1349	GSPEAPASPEREEVA
S1358	EREEVALSEYKTETY
T1362	VALSEYKTETYDDYK
T1364	LSEYKTETYDDYKDE
Y1365	SEYKTETYDDYKDET
S1417	EKEARRSSLEKHRkE
K1423-a	SSLEKHRkEKPFKTG
S1435	KTGRGRISTPERKVA
T1436	TGRGRISTPERKVAK
K1444	PERKVAKKEPSTVSR
S1476	KTEVQAHSPSRKFIL
S1478	EVQAHSPSRKFILKP
K1484	PSRKFILKPAIKYTR
T1490	LKPAIKYTRPTHLSC
T1493	AIKYTRPTHLSCVKR
S1496	YTRPTHLSCVKRKTT
K1499	PTHLSCVKRKTTAAG
K1501	HLSCVKRKTTAAGGE
T1502	LSCVKRKTTAAGGES
T1503	SCVKRKTTAAGGESA
G1506	KRKTTAAGGESALAP
K1517	ALAPSVFKQAKDKVS
K1520	PSVFKQAKDKVSDGV
-	gap
-	gap
-	gap
S1524	KQAKDKVSDGVTKSP
T1528	DKVSDGVTKSPEKRS
S1530	VSDGVTKSPEKRSSL
S1535	TKSPEKRSSLPRPSS
S1536	KSPEKRSSLPRPSSI
S1551	LPPRRGVSGDRDENS
S1560	DRDENSFSLNSSISS
T1573	SSSARRTTRSEPIRR
S1584	PIRRAGKSGTStPTT
T1586	RRAGKSGTStPTTPG
S1587	RAGKSGTStPTTPGS
T1588-p	AGKSGTStPTTPGST
T1590	KSGTStPTTPGSTAI
T1591	SGTStPTTPGSTAIT
S1594	StPTTPGSTAITPGT
T1595	tPTTPGSTAITPGTP
T1598	TPGSTAITPGTPPSY
T1601	STAITPGTPPSYSSR
S1604	ITPGTPPSYSSRTPG
Y1605	TPGTPPSYSSRTPGT
S1606	PGTPPSYSSRTPGTP
S1607	GTPPSYSSRTPGTPG
T1609	PPSYSSRTPGTPGTP
T1612	YSSRTPGTPGTPSYP
T1615	RTPGTPGTPSYPRTP
S1617	PGTPGTPSYPRTPHT
Y1618	GTPGTPSYPRTPHTP
T1624	SYPRTPHTPGTPKSA
T1627	RTPHTPGTPKSAILV
S1630	HTPGTPKSAILVPSE
T1645	KKVAIIRTPPKSPAT
S1649	IIRTPPKSPATPKQL
T1652	TPPKSPATPKQLRLI
S1675	NVKSKIGSTDNIKYQ
-	gap
T1692	GGQVQIVTKKIDLSH
K1693	GQVQIVTKKIDLSHV
S1698	VTKKIDLSHVTSKCG
S1702	IDLSHVTSKCGSLKN
S1706	HVTSKCGSLKNIRHR
T1776	DHGAEIITQSPGRSS
S1778	GAEIITQSPGRSSVA
G1780	EIITQSPGRSSVASP
S1782	ITQSPGRSSVASPRR
S1783	TQSPGRSSVASPRRL
S1786	PGRSSVASPRRLSNV
S1791	VASPRRLSNVSSSGS
S1794	PRRLSNVSSSGSINL
S1795	RRLSNVSSSGSINLL
S1796	RLSNVSSSGSINLLE
S1798	SNVSSSGSINLLESP
S1804	GSINLLESPQLATLA
T1809	LESPQLATLAEDVTA
T1815	ATLAEDVTAALAKQG

	MAP2 iso4
P28	EASAHSHPPEIKDQG
Y50	RSANGFPYREDEEGA
S63	GAFGEHGSQGTYSNT
T66	GEHGSQGTYSNTKEN
Y67	EHGSQGTYSNTKENG
T130	LPLAAEETANLPPSP
S136	ETANLPPSPPPSPAS
S140	LPPSPPPSPASEQTV
S143	SPPPSPASEQTVTVE
T146	PSPASEQTVTVEEAA
T148	PASEQTVTVEEAAGG
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G154	VTVEEAAGGESALAP
K165	ALAPSVFKQAKDKVS
K168	PSVFKQAKDKVSNST
T203-p	PSTTKRAtFsDSLLI
S205-p	TTKRAtFsDSLLIQP
S214-p	SLLIQPTsAGSTDRL
-	gap
T233	SGNKDGVTKSPEKRS
S235	NKDGVTKSPEKRSSL
S240	TKSPEKRSSLPRPSS
S241	KSPEKRSSLPRPSSI
S256	LPPRRGVSGDRDENS
S265	DRDENSFSLNSSISS
T278	SSSARRTTRSEPIRR
S289	PIRRAGKSGTSTPTT
T291	RRAGKSGTSTPTTPG
S292	RAGKSGTSTPTTPGS
T293	AGKSGTSTPTTPGST
T295	KSGTSTPTTPGSTAI
T296	SGTSTPTTPGSTAIT
S299	STPTTPGSTAITPGT
T300	TPTTPGSTAITPGTP
T303	TPGSTAITPGTPPSY
T306	STAITPGTPPSYSSR
S309	ITPGTPPSYSSRTPG
Y310	TPGTPPSYSSRTPGT
S311	PGTPPSYSSRTPGTP
S312	GTPPSYSSRTPGTPG
T314	PPSYSSRTPGTPGTP
T317	YSSRTPGTPGTPSYP
T320	RTPGTPGTPSYPRTP
S322	PGTPGTPSYPRTPHT
Y323	GTPGTPSYPRTPHTP
T329	SYPRTPHTPGTPKSA
T332	RTPHTPGTPKSAILV
S335	HTPGTPKSAILVPSE
T350	KKVAIIRTPPKSPAT
S354	IIRTPPKSPATPKQL
T357	TPPKSPATPKQLRLI
S380	NVKSKIGSTDNIKYQ
S418-p	SKDNIKHsAGGGNVQ
T428-p	GGNVQIVtKKIDLSH
K429	GNVQIVtKKIDLSHV
S434	VtKKIDLSHVTSKCG
S438	IDLSHVTSKCGSLKN
S442	HVTSKCGSLKNIRHR
T512	DHGAEIITQSPGRSS
S514	GAEIITQSPGRSSVA
G516	EIITQSPGRSSVASP
S518	ITQSPGRSSVASPRR
S519	TQSPGRSSVASPRRL
S522	PGRSSVASPRRLSNV
S527	VASPRRLSNVSSSGS
S530	PRRLSNVSSSGSINL
S531	RRLSNVSSSGSINLL
S532	RLSNVSSSGSINLLE
S534	SNVSSSGSINLLESP
S540	GSINLLESPQLATLA
T545	LESPQLATLAEDVTA
T551	ATLAEDVTAALAKQG

	mouse ► Hide Isoforms
S28-p	EAAAHPHsPEMKDQG
Y50	RNANGFPYREEEEGA
S63	GAFGEHRSQGTYSDT
T66	GEHRSQGTYSDTKEN
Y67	EHRSQGTYSDTKENG
T130-p	LPLAAEEtANLPPsP
S136-p	EtANLPPsPPPsPAs
S140-p	LPPsPPPsPAsEQtA
S143-p	sPPPsPAsEQtAtVE
T146-p	PsPAsEQtAtVEEDL
T148-p	PAsEQtAtVEEDLLT
K218-a	LQGMEGEkLPPVPFA
S283-p	WGLAAPIsPGPLtPM
T288-p	PIsPGPLtPMREKDV
S313-p	QFDSPMPsPFHGGsF
S319-p	PsPFHGGsFTLPLDT
T321	PFHGGsFTLPLDTMk
K328-u	TLPLDTMkNERVsEG
S333-p	TMkNERVsEGPRPFA
S365-p	LATSKESsKDEEPLK
S447-p	LDEKSTVsIEEAVAK
S476-p	IQTSTEQsFSKEDQK
S496-p	IDELKQDsFPISLEQ
T514	DAAMTSKTLGKVTsE
S520-p	KTLGKVTsEPEAVSE
S550-p	NKLEGAGsATIAEVE
K577-u	YFETSALkEDMTRst
S583-p	LkEDMTRstELGSDY
T584-p	kEDMTRstELGSDYY
Y590	stELGSDYYELsDsR
S594-p	GSDYYELsDsRGsAQ
S596-p	DYYELsDsRGsAQEs
S599-p	ELsDsRGsAQEsLDt
S603-p	sRGsAQEsLDtIsPK
T606-p	sAQEsLDtIsPKNQH
S608-p	QEsLDtIsPKNQHDE
S626-p	QAKASQPsPPAQEAG
S654-p	SELPEEPssPQERMF
S655-p	ELPEEPssPQERMFT
S685-p	NKDDLTLsRSLGLGG
S726-p	FGRGHDLsPLAsDIL
S730-p	HDLsPLAsDILtNts
T734-p	PLAsDILtNtsGsMD
T736-p	AsDILtNtsGsMDEG
S737-p	sDILtNtsGsMDEGD
S739-p	ILtNtsGsMDEGDDy
Y746-p	sMDEGDDyLPPTTPA
T777-g	KAEQAKVtGGQTIQV
K795-u	SESPFPAkEYYKNGT
S819-p	LDLAGTRsRLAsVsA
S823-p	GTRsRLAsVsADAEV
S825-p	RsRLAsVsADAEVAR
S835-p	AEVARRKsVPSEAML
S845	SEAMLAESSTSLPPV
T859-p	VADESPVtVKPDSQL
P862	ESPVtVKPDSQLEDM
S864	PVtVKPDSQLEDMGY
K905-u	FYEGTDDkVRRDLAT
S915-p	RDLATDLsLIEVkLA
K920-u	DLsLIEVkLAAAGRV
S938-p	FTAEKEAsPPTSADK
T1012-p	ELITTKDtsPEKtEk
S1013-p	LITTKDtsPEKtEkG
T1017-p	KDtsPEKtEkGLssV
K1019-u	tsPEKtEkGLssVPE
S1022-p	EKtEkGLssVPEVAE
S1023-p	KtEkGLssVPEVAEV
T1033-p	EVAEVEPttkADQGL
T1034-p	VAEVEPttkADQGLD
K1035-u	AEVEPttkADQGLDF
K1046-u	GLDFAATkAEPSQLD
N1112	IKEGGKVNETEVKEK
T1114	EGGKVNETEVKEKVT
S1136-p	EAVDKEEsyEssGEH
Y1137-p	AVDKEEsyEssGEHE
S1139-p	DKEEsyEssGEHEsL
S1140-p	KEEsyEssGEHEsLT
S1145-p	EssGEHEsLTMEsLK
S1150-p	HEsLTMEsLKPDEGk
K1157-m1	sLKPDEGkkEtsPEt
K1158-m1	LKPDEGkkEtsPEts
T1160-p	PDEGkkEtsPEtsLI
S1161-p	DEGkkEtsPEtsLIQ
T1164-p	kkEtsPEtsLIQDEV
S1165-p	kEtsPEtsLIQDEVA
S1240-p	SEPAEVPsEEEEIEA
S1258-p	YDKLLFRsDtLQISD
T1260-p	KLLFRsDtLQISDLL
R1330	PEEERRPRPHDEELE
S1352-p	QAEPKDGsPDAPAtP
T1358-p	GsPDAPAtPEKEEVA
S1367-p	EKEEVAFsEYKTETY
T1371	VAFsEYKTETYDDYK
T1373	FsEYKTETYDDYKDE
Y1374	sEYKTETYDDYKDET
S1426-p	EKDARRPsLEKHRKE
K1432	PsLEKHRKEKPFKTG
S1444-p	KTGRGRIstPERKVA
T1445-p	TGRGRIstPERKVAK
K1453	PERKVAKKEPSTVSR
S1485-p	KSEVQAHsPsRKLIL
S1487-p	EVQAHsPsRKLILkP
K1493-u	PsRKLILkPAIKYTR
T1499	LkPAIKYTRPTHLSC
T1502	AIKYTRPTHLSCVKR
S1505	YTRPTHLSCVKRKtt
K1508	PTHLSCVKRKttAAs
K1510	HLSCVKRKttAAsGD
T1511-p	LSCVKRKttAAsGDL
T1512-p	SCVKRKttAAsGDLA
S1515-p	KRKttAAsGDLAQAP
K1526	AQAPGAFKQAKDKVt
K1529	PGAFKQAKDKVtDGI
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T1533-p	KQAKDKVtDGIsKsP
S1537-p	DKVtDGIsKsPEKRs
S1539-p	VtDGIsKsPEKRssL
S1544-p	sKsPEKRssLPRPSS
S1545-p	KsPEKRssLPRPSSI
S1560-p	LPPRRGVsGDREENS
S1569	DREENSFSLNSSISS
T1581	ISSARRTTRSEPIRR
S1592-p	PIRRAGKsGtstPtt
T1594-p	RRAGKsGtstPttPG
S1595-p	RAGKsGtstPttPGs
T1596-p	AGKsGtstPttPGst
T1598-p	KsGtstPttPGstAI
T1599-p	sGtstPttPGstAIt
S1602-p	stPttPGstAItPGt
T1603-p	tPttPGstAItPGtP
T1606-p	tPGstAItPGtPPsy
T1609-p	stAItPGtPPsyssR
S1612-p	ItPGtPPsyssRtPG
Y1613-p	tPGtPPsyssRtPGt
S1614-p	PGtPPsyssRtPGtP
S1615-p	GtPPsyssRtPGtPG
T1617-p	PPsyssRtPGtPGtP
T1620-p	yssRtPGtPGtPsyP
T1623-p	RtPGtPGtPsyPRtP
S1625-p	PGtPGtPsyPRtPGt
Y1626-p	GtPGtPsyPRtPGtP
T1629-p	GtPsyPRtPGtPKsG
T1632-p	syPRtPGtPKsGILV
S1635-p	RtPGtPKsGILVPSE
T1650-p	KKVAIIRtPPKsPAt
S1654-p	IIRtPPKsPAtPKQL
T1657-p	tPPKsPAtPKQLRLI
S1680-p	NVKSKIGsTDNIKYQ
-	gap
T1697	GGQVQIVTkKIDLSH
K1698-u	GQVQIVTkKIDLSHV
S1703	VTkKIDLSHVTSKCG
S1707	IDLSHVTSKCGSLKN
S1711	HVTSKCGSLKNIRHR
T1781-p	DHGAEIItQsPsRss
S1783-p	GAEIItQsPsRssVA
S1785-p	EIItQsPsRssVAsP
S1787-p	ItQsPsRssVAsPRR
S1788-p	tQsPsRssVAsPRRL
S1791-p	PsRssVAsPRRLsNV
S1796-p	VAsPRRLsNVsssGs
S1799-p	PRRLsNVsssGsINL
S1800-p	RRLsNVsssGsINLL
S1801-p	RLsNVsssGsINLLE
S1803-p	sNVsssGsINLLEsP
S1809-p	GsINLLEsPQLATLA
T1814	LEsPQLATLAEDVTA
T1820	ATLAEDVTAALAKQG

	MAP2 iso2
S28-p	EAAAHPHsPEMKDQG
Y50	RNANGFPYREEEEGA
S63	GAFGEHRSQGTYSDT
T66	GEHRSQGTYSDTKEN
Y67	EHRSQGTYSDTKENG
T130	LPLAAEETANLPPsP
S136-p	ETANLPPsPPPsPAs
S140-p	LPPsPPPsPAsEQtA
S143-p	sPPPsPAsEQtAtVE
T146-p	PsPAsEQtAtVEEDL
T148-p	PAsEQtAtVEEDLLT
K218-a	LQGMEGEkLPPVPFA
S283-p	WGLAAPIsPGPLtPM
T288-p	PIsPGPLtPMREKDV
S313	QFDSPMPSPFHGGSF
S319	PSPFHGGSFTLPLDT
T321	PFHGGSFTLPLDTMK
K328	TLPLDTMKNERVSEG
S333	TMKNERVSEGPRPFA
S365	LATSKESSKDEEPLK
S447-p	LDEKSTVsIEEAVAK
S476-p	IQTSTEQsFSKEDQK
S496-p	IDELKQDsFPISLEQ
T514	DAAMTSKTLGKVTSE
S520	KTLGKVTSEPEAVSE
S550-p	NKLEGAGsATIAEVE
K577	YFETSALKEDMTRsT
S583-p	LKEDMTRsTELGSDY
T584	KEDMTRsTELGSDYY
Y590	sTELGSDYYELsDsR
S594-p	GSDYYELsDsRGsAQ
S596-p	DYYELsDsRGsAQEs
S599-p	ELsDsRGsAQEsLDT
S603-p	sRGsAQEsLDTIsPK
T606	sAQEsLDTIsPKNQH
S608-p	QEsLDTIsPKNQHDE
S626-p	QAKASQPsPPAQEAG
S654-p	SELPEEPssPQERMF
S655-p	ELPEEPssPQERMFT
S685	NKDDLTLSRSLGLGG
S726-p	FGRGHDLsPLAsDIL
S730-p	HDLsPLAsDILtNts
T734-p	PLAsDILtNtsGsMD
T736-p	AsDILtNtsGsMDEG
S737-p	sDILtNtsGsMDEGD
S739-p	ILtNtsGsMDEGDDy
Y746-p	sMDEGDDyLPPTTPA
T777	KAEQAKVTGGQTIQV
K795	SESPFPAKEYYKNGT
S819	LDLAGTRSRLAsVSA
S823-p	GTRSRLAsVSADAEV
S825	RSRLAsVSADAEVAR
S835-p	AEVARRKsVPSEAML
S845	SEAMLAESSTSLPPV
T859-p	VADESPVtVKPDSQL
P862	ESPVtVKPDSQLEDM
S864	PVtVKPDSQLEDMGY
K905	FYEGTDDKVRRDLAT
S915	RDLATDLSLIEVKLA
K920	DLSLIEVKLAAAGRV
S938-p	FTAEKEAsPPTSADK
T1012	ELITTKDTSPEKTEK
S1013	LITTKDTSPEKTEKG
T1017	KDTSPEKTEKGLSSV
K1019	TSPEKTEKGLSSVPE
S1022	EKTEKGLSSVPEVAE
S1023	KTEKGLSSVPEVAEV
T1033	EVAEVEPTTKADQGL
T1034	VAEVEPTTKADQGLD
K1035	AEVEPTTKADQGLDF
K1046	GLDFAATKAEPSQLD
N1112	IKEGGKVNETEVKEK
T1114	EGGKVNETEVKEKVT
S1136-p	EAVDKEEsyEssGEH
Y1137-p	AVDKEEsyEssGEHE
S1139-p	DKEEsyEssGEHEsL
S1140-p	KEEsyEssGEHEsLT
S1145-p	EssGEHEsLTMEsLK
S1150-p	HEsLTMEsLKPDEGK
K1157	sLKPDEGKKETsPEt
K1158	LKPDEGKKETsPEts
T1160	PDEGKKETsPEtsLI
S1161-p	DEGKKETsPEtsLIQ
T1164-p	KKETsPEtsLIQDEV
S1165-p	KETsPEtsLIQDEVA
S1240-p	SEPAEVPsEEEEIEA
S1258	YDKLLFRSDtLQISD
T1260-p	KLLFRSDtLQISDLL
R1330	PEEERRPRPHDEELE
S1352-p	QAEPKDGsPDAPAtP
T1358-p	GsPDAPAtPEKEEVA
S1367	EKEEVAFSEYKTETY
T1371	VAFSEYKTETYDDYK
T1373	FSEYKTETYDDYKDE
Y1374	SEYKTETYDDYKDET
S1426	EKDARRPSL______
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