Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteCuration ProcessContact
NIH-logos NIGMS Logo NIAAA Logo NCI Logo NIH Logo
Protein Page:
Tau (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
Tau a microtubule-associated protein that regulates microtubule assembly and stability. Apparently involved in the establishment and maintenance of neuronal polarity. Mutations can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. Nine differentially spliced isoforms have been described. The short isoforms allow plasticity of the cytoskeleton, whereas the longer isoforms may preferentially play a role in its stabilization. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal protein
Cellular Component: microtubule; microtubule associated complex; growth cone; axon; tubulin complex; plasma membrane; cytosol
Molecular Function: protein binding; enzyme binding; structural constituent of cytoskeleton; microtubule binding; apolipoprotein binding; SH3 domain binding; protein kinase binding
Biological Process: apoptosis; axon extension; positive regulation of microtubule polymerization; positive regulation of axon extension; neuron migration; axon cargo transport; microtubule cytoskeleton organization and biogenesis; adult walking behavior; regulation of microtubule polymerization; mitochondrion transport along microtubule; negative regulation of intracellular transport; generation of neurons; regulation of autophagy; cell structure disassembly during apoptosis
Reference #:  P10636 (UniProtKB)
Alt. Names/Synonyms: DDPAC; FLJ31424; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPT; MAPTL; MGC138549; Microtubule-associated protein tau; MSTD; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau; PPND; TAU
Gene Symbols: MAPT
Molecular weight: 78,928 Da
Basal Isoelectric point: 6.25  Predict pI for various phosphorylation states
CST Pathways:  Alzheimer's Disease  |  Microtubule Dynamics  |  Regulation of P38 MAPKs
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

Tau

Protein Structure Not Found.


STRING  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  DISEASE  |  Scansite  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  Source  |  UCSD-Nature  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene


Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

► Hide Isoforms
 
0 1 T17 VMEDHAGTyGLGDRK
5 1 Y18-p MEDHAGTyGLGDRKD
1 0 Y29 DRKDQGGYTMHQDQE
1 1 T39 HQDQEGDTDAGLKEs
1 0 K44 GDTDAGLKEsPLQtP
2 4 S46-p TDAGLKEsPLQtPTE
2 2 T50-p LKEsPLQtPTEDGSE
0 1 T52 EsPLQtPTEDGSEEP
0 1 S56 QtPTEDGSEEPGSET
0 1 S61 DGSEEPGSETSDAKS
0 1 T63 SEEPGSETSDAKSTP
0 1 S64 EEPGSETSDAKSTPT
0 2 S68 SETSDAKSTPTAEDV
0 3 T69 ETSDAKSTPTAEDVT
1 1 T71 SDAKSTPTAEDVTAP
0 1 T95 QAAAQPHTEIPEGTT
0 1 T101 HTEIPEGTTAEEAGI
0 1 T102 TEIPEGTTAEEAGIG
1 5 T111 EEAGIGDTPSLEDEA
0 2 S113 AGIGDTPSLEDEAAG
1 0 T123 DEAAGHVTQEPESGK
0 1 T123 DEAAGHVTQEPESGK
0 7 S171-p REATRQPsGtGPEDT
0 1 T173-p ATRQPsGtGPEDTEG
0 4 S214 GGKERPGSKEEVDED
0 1 S235 SPQDSPPSKAsPAQD
0 1 S238-p DSPPSKAsPAQDGRP
0 2 S382 KARMVSKSKDGtGsD
0 3 T386-p VSKSKDGtGsDDKKA
0 2 S388-p KSKDGtGsDDKKAKT
0 2 S411-p LKNRPCLsPKHPTPG
0 1 T449-p VSSVTSRtGsSGAKE
0 1 S451-p SVTSRtGsSGAKEMK
1 2 T466-p LKGADGKtKIATPRG
3 1 T470 DGKtKIATPRGAAPP
0 2 P476 ATPRGAAPPGQKGQA
1 0 K480 GAAPPGQKGQANATR
0 1 Q482 APPGQKGQANATRIP
2 1 T486 QKGQANATRIPAKtP
1 0 K491 NATRIPAKtPPAPKt
5 4 T492-p ATRIPAKtPPAPKtP
1 4 P493 TRIPAKtPPAPKtPP
1 6 A495 IPAKtPPAPKtPPss
1 0 K497 AKtPPAPKtPPssGE
40 39 T498-p KtPPAPKtPPssGEP
3 4 S501-p PAPKtPPssGEPPKs
2 5 S502-p APKtPPssGEPPKsG
0 11 S508-p ssGEPPKsGDRsGys
5 16 S512-p PPKsGDRsGyssPGs
4 39 Y514-p KsGDRsGyssPGsPG
16 20 S515-p sGDRsGyssPGsPGt
65 50 S516-p GDRsGyssPGsPGtP
90 143 S519-p sGyssPGsPGtPGsR
59 39 T522-p ssPGsPGtPGsRSRt
2 0 S525 GsPGtPGSRSRtPsL
1 8 S525-p GsPGtPGsRSRtPsL
2 4 S527 PGtPGsRSRtPsLPt
33 15 T529-p tPGsRSRtPsLPtPP
43 53 S531-p GsRSRtPsLPtPPtR
19 24 T534-p SRtPsLPtPPtREPK
1 6 T537-p PsLPtPPtREPKKVA
78 31 T548-p KKVAVVRtPPKsPss
31 42 S552-p VVRtPPKsPssAKsR
2 8 S554-p RtPPKsPssAKsRLQ
1 0 S555 tPPKsPsSAKsRLQT
2 4 S555-p tPPKsPssAKsRLQT
1 1 A556 PPKsPssAKsRLQTA
2 3 S558-p KsPssAKsRLQTAPV
2 1 T562 sAKsRLQTAPVPMPD
1 0 K571 PVPMPDLKNVKSKIG
2 1 K571 PVPMPDLKNVKSKIG
2 1 S575 PDLKNVKSKIGsTEN
0 1 K576 DLKNVKSKIGsTENL
74 9 S579-p NVKSKIGsTENLKHQ
1 2 T580 VKSKIGsTENLKHQP
1 0 K584 IGsTENLKHQPGGGK
1 0 K591 KHQPGGGKVQIINKK
2 0 K597 GKVQIINKKLDLSNV
0 1 K598 KVQIINKKLDLSNVQ
0 1 S602 INKKLDLSNVQSKCG
1 2 S606 LDLSNVQSKCGSKDN
1 0 K607 DLSNVQSKCGSKDNI
0 1 K607 DLSNVQSKCGSKDNI
5 0 S610 NVQSKCGSKDNIKHV
2 1 S622 KHVPGGGSVQIVykP
2 17 Y627-p GGSVQIVykPVDLsK
0 4 K628-ac GSVQIVykPVDLsKV
2 1 K628 GSVQIVyKPVDLsKV
1 1 S633-p VykPVDLsKVtSKCG
0 1 T636-p PVDLsKVtSKCGsLG
3 0 S637 VDLsKVtSKCGsLGN
6 4 S641-p KVtSKCGsLGNIHHK
1 0 K657 GGGQVEVKSEKLDFK
0 1 S658 GGQVEVKSEKLDFKD
2 1 S669 DFKDRVQSKIGsLDN
2 0 K670 FKDRVQSKIGsLDNI
21 11 S673-p RVQSKIGsLDNITHV
1 0 S673 RVQSKIGSLDNITHV
0 1 T678 IGsLDNITHVPGGGN
0 27 K686-ac HVPGGGNkkIETHKL
0 17 K687-ac VPGGGNkkIETHKLT
1 1 T690 GGNkkIETHKLTFRE
1 1 T694 kIETHKLTFRENAKA
2 1 T703 RENAKAKTDHGAEIV
2 41 Y711-p DHGAEIVyKsPVVsG
102 116 S713-p GAEIVyKsPVVsGDt
12 93 S717-p VyKsPVVsGDtsPRH
3 0 S717 VyKsPVVSGDtsPRH
4 48 T720-p sPVVsGDtsPRHLsN
89 104 S721-p PVVsGDtsPRHLsNV
11 12 S726-p DtsPRHLsNVsstGs
1 9 S729-p PRHLsNVsstGsIDM
4 6 S730-p RHLsNVsstGsIDMV
1 8 T731-p HLsNVsstGsIDMVD
4 7 S733-p sNVsstGsIDMVDsP
29 4 S739-p GsIDMVDsPQLAtLA
2 3 T744-p VDsPQLAtLADEVSA
0 1 S750 AtLADEVSASLAKQG
0 1 S752 LADEVSASLAKQGL_
5383 : Phospho-Tau (Thr181) Antibody
12885 : Phospho-Tau (Thr181) (D9F4G) Rabbit mAb
11834 : Phospho-Tau (Ser202) Antibody
9632 : Phospho-Tau (Ser396) (PHF13) Mouse mAb
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
  Tau iso2  
T17 VMEDHAGTYGLGDRK
Y18 MEDHAGTYGLGDRKD
Y29 DRKDQGGYTMHQDQE
T39 HQDQEGDTDAGLKAE
K44 GDTDAGLKAEEAGIG
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
T53 EEAGIGDTPSLEDEA
S55 AGIGDTPSLEDEAAG
T65 DEAAGHVTQARMVSK
T65 DEAAGHVTQARMVSK
- gap
- gap
- gap
- gap
- gap
S73-p QARMVSKsKDGtGSD
T77-p VSKsKDGtGSDDKKA
S79 KsKDGtGSDDKKAKG
- gap
- gap
- gap
T91 AKGADGKTKIATPRG
T95 DGKTKIATPRGAAPP
P101 ATPRGAAPPGQKGQA
K105 GAAPPGQKGQANATR
Q107 APPGQKGQANATRIP
T111 QKGQANATRIPAKTP
K116 NATRIPAKTPPAPKT
T117 ATRIPAKTPPAPKTP
P118 TRIPAKTPPAPKTPP
A120 IPAKTPPAPKTPPSS
K122 AKTPPAPKTPPSSGE
T123 KTPPAPKTPPSSGEP
S126 PAPKTPPSSGEPPKS
S127 APKTPPSSGEPPKSG
S133 SSGEPPKSGDRSGYS
S137 PPKSGDRSGYSSPGS
Y139 KSGDRSGYSSPGSPG
S140 SGDRSGYSSPGSPGT
S141 GDRSGYSSPGSPGTP
S144 SGYSSPGSPGTPGSR
T147 SSPGSPGTPGSRSRt
S150 GSPGTPGSRSRtPsL
S150 GSPGTPGSRSRtPsL
S152 PGTPGSRSRtPsLPT
T154-p TPGSRSRtPsLPTPP
S156-p GSRSRtPsLPTPPTR
T159 SRtPsLPTPPTREPK
T162 PsLPTPPTREPKKVA
T173-p KKVAVVRtPPKsPSS
S177-p VVRtPPKsPSSAKSR
S179 RtPPKsPSSAKSRLQ
S180 tPPKsPSSAKSRLQT
S180 tPPKsPSSAKSRLQT
A181 PPKsPSSAKSRLQTA
S183 KsPSSAKSRLQTAPV
T187 SAKSRLQTAPVPMPD
K196 PVPMPDLKNVKSKIG
K196 PVPMPDLKNVKSKIG
S200 PDLKNVKSKIGSTEN
K201 DLKNVKSKIGSTENL
S204 NVKSKIGSTENLKHQ
T205 VKSKIGSTENLKHQP
K209 IGSTENLKHQPGGGK
K216 KHQPGGGKVQIVYKP
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
Y221 GGKVQIVYKPVDLsK
K222 GKVQIVYKPVDLsKV
K222 GKVQIVYKPVDLsKV
S227-p VYKPVDLsKVtSKCG
T230-p PVDLsKVtSKCGsLG
S231 VDLsKVtSKCGsLGN
S235-p KVtSKCGsLGNIHHK
K251 GGGQVEVKSEKLDFK
S252 GGQVEVKSEKLDFKD
S263 DFKDRVQSKIGsLDN
K264 FKDRVQSKIGsLDNI
S267-p RVQSKIGsLDNITHV
S267 RVQSKIGSLDNITHV
T272 IGsLDNITHVPGGGN
K280-ac HVPGGGNkkIETHKL
K281-ac VPGGGNkkIETHKLT
T284 GGNkkIETHKLTFRE
T288 kIETHKLTFRENAKA
T297 RENAKAKTDHGAEIV
Y305 DHGAEIVYKsPVVSG
S307-p GAEIVYKsPVVSGDT
S311 VYKsPVVSGDTsPRH
S311 VYKsPVVSGDTsPRH
T314 sPVVSGDTsPRHLsN
S315-p PVVSGDTsPRHLsNV
S320-p DTsPRHLsNVSSTGS
S323 PRHLsNVSSTGSIDM
S324 RHLsNVSSTGSIDMV
T325 HLsNVSSTGSIDMVD
S327 sNVSSTGSIDMVDSP
S333 GSIDMVDSPQLATLA
T338 VDSPQLATLADEVSA
S344 ATLADEVSASLAKQG
S346 LADEVSASLAKQGL_
5383 : Phospho-Tau (Thr181) Antibody
12885 : Phospho-Tau (Thr181) (D9F4G) Rabbit mAb
11834 : Phospho-Tau (Ser202) Antibody
9632 : Phospho-Tau (Ser396) (PHF13) Mouse mAb
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
  Tau iso3  
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
T17 REAGIGDTPSLEDEA
S19 AGIGDTPSLEDEAAG
T29 DEAAGHVTQARMVSK
T29 DEAAGHVTQARMVSK
- gap
- gap
- gap
- gap
- gap
S37 QARMVSKSKDGTGSD
T41 VSKSKDGTGSDDKKA
S43 KSKDGTGSDDKKAKG
- gap
- gap
- gap
T55 AKGADGKTKIATPRG
T59 DGKTKIATPRGAAPP
P65 ATPRGAAPPGQKGQA
K69 GAAPPGQKGQANATR
Q71 APPGQKGQANATRIP
T75 QKGQANATRIPAKTP
K80 NATRIPAKTPPAPKT
T81 ATRIPAKTPPAPKTP
P82 TRIPAKTPPAPKTPP
A84 IPAKTPPAPKTPPSS
K86 AKTPPAPKTPPSSGE
T87 KTPPAPKTPPSSGEP
S90 PAPKTPPSSGEPPKS
S91 APKTPPSSGEPPKSG
S97 SSGEPPKSGDRSGYs
S101 PPKSGDRSGYssPGs
Y103 KSGDRSGYssPGsPG
S104-p SGDRSGYssPGsPGT
S105-p GDRSGYssPGsPGTP
S108-p SGYssPGsPGTPGSR
T111 ssPGsPGTPGSRSRt
S114 GsPGTPGSRSRtPsL
S114 GsPGTPGSRSRtPsL
S116 PGTPGSRSRtPsLPT
T118-p TPGSRSRtPsLPTPP
S120-p GSRSRtPsLPTPPTR
T123 SRtPsLPTPPTREPK
T126 PsLPTPPTREPKKVA
T137-p KKVAVVRtPPKsPSS
S141-p VVRtPPKsPSSAKSR
S143 RtPPKsPSSAKSRLQ
S144 tPPKsPSSAKSRLQT
S144 tPPKsPSSAKSRLQT
A145 PPKsPSSAKSRLQTA
S147 KsPSSAKSRLQTAPV
T151 SAKSRLQTAPVPMPD
K160 PVPMPDLKNVKSKIG
K160 PVPMPDLKNVKSKIG
S164 PDLKNVKSKIGSTEN
K165 DLKNVKSKIGSTENL
S168 NVKSKIGSTENLKHQ
T169 VKSKIGSTENLKHQP
K173 IGSTENLKHQPGGGK
K180 KHQPGGGKVQIVYKP
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
Y185 GGKVQIVYKPVDLsK
K186 GKVQIVYKPVDLsKV
K186 GKVQIVYKPVDLsKV
S191-p VYKPVDLsKVtSKCG
T194-p PVDLsKVtSKCGsLG
S195 VDLsKVtSKCGsLGN
S199-p KVtSKCGsLGNIHHK
K215 GGGQVEVKSEKLDFK
S216 GGQVEVKSEKLDFKD
S227 DFKDRVQSKIGSLDN
K228 FKDRVQSKIGSLDNI
S231 RVQSKIGSLDNITHV
S231 RVQSKIGSLDNITHV
T236 IGSLDNITHVPGGGN
K244-ac HVPGGGNkkIETHKL
K245-ac VPGGGNkkIETHKLT
T248 GGNkkIETHKLTFRE
T252 kIETHKLTFRENAKA
T261 RENAKAKTDHGAEIV
Y269 DHGAEIVYKsPVVSG
S271-p GAEIVYKsPVVSGDT
S275 VYKsPVVSGDTsPRH
S275 VYKsPVVSGDTsPRH
T278 sPVVSGDTsPRHLsN
S279-p PVVSGDTsPRHLsNV
S284-p DTsPRHLsNVSsTGS
S287 PRHLsNVSsTGSIDM
S288-p RHLsNVSsTGSIDMV
T289 HLsNVSsTGSIDMVD
S291 sNVSsTGSIDMVDsP
S297-p GSIDMVDsPQLATLA
T302 VDsPQLATLADEVSA
S308 ATLADEVSASLAKQG
S310 LADEVSASLAKQGL_
5383 : Phospho-Tau (Thr181) Antibody
12885 : Phospho-Tau (Thr181) (D9F4G) Rabbit mAb
11834 : Phospho-Tau (Ser202) Antibody
9632 : Phospho-Tau (Ser396) (PHF13) Mouse mAb
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
  Tau iso5  
T17 VMEDHAGTYGLGDRK
Y18 MEDHAGTYGLGDRKD
Y29 DRKDQGGYTMHQDQE
T39 HQDQEGDTDAGLKES
K44 GDTDAGLKESPLQTP
S46 TDAGLKESPLQTPTE
T50 LKESPLQTPTEDGSE
T52 ESPLQTPTEDGSEEP
S56 QTPTEDGSEEPGSET
S61 DGSEEPGSETSDAKS
T63 SEEPGSETSDAKSTP
S64 EEPGSETSDAKSTPT
S68 SETSDAKSTPTAEDV
T69 ETSDAKSTPTAEDVT
T71 SDAKSTPTAEDVTAP
T95 QAAAQPHTEIPEGTT
T101 HTEIPEGTTAEEAGI
T102 TEIPEGTTAEEAGIG
T111 EEAGIGDTPSLEDEA
S113 AGIGDTPSLEDEAAG
T123 DEAAGHVTQARMVSK
T123 DEAAGHVTQARMVSK
- gap
- gap
- gap
- gap
- gap
S131 QARMVSKSKDGTGSD
T135 VSKSKDGTGSDDKKA
S137 KSKDGTGSDDKKAKG
- gap
- gap
- gap
T149 AKGADGKTKIATPRG
T153 DGKTKIATPRGAAPP
P159 ATPRGAAPPGQKGQA
K163 GAAPPGQKGQANATR
Q165 APPGQKGQANATRIP
T169 QKGQANATRIPAKTP
K174 NATRIPAKTPPAPKt
T175 ATRIPAKTPPAPKtP
P176 TRIPAKTPPAPKtPP
A178 IPAKTPPAPKtPPsS
K180 AKTPPAPKtPPsSGE
T181-p KTPPAPKtPPsSGEP
S184-p PAPKtPPsSGEPPKS
S185 APKtPPsSGEPPKSG
S191 sSGEPPKSGDRsGYs
S195-p PPKSGDRsGYssPGs
Y197 KSGDRsGYssPGsPG
S198-p SGDRsGYssPGsPGt
S199-p GDRsGYssPGsPGtP
S202-p sGYssPGsPGtPGSR
T205-p ssPGsPGtPGSRSRt
S208 GsPGtPGSRSRtPsL
S208 GsPGtPGSRSRtPsL
S210 PGtPGSRSRtPsLPT
T212-p tPGSRSRtPsLPTPP
S214-p GSRSRtPsLPTPPTR
T217 SRtPsLPTPPTREPK
T220 PsLPTPPTREPKKVA
T231-p KKVAVVRtPPKsPSS
S235-p VVRtPPKsPSSAKSR
S237 RtPPKsPSSAKSRLQ
S238 tPPKsPSSAKSRLQT
S238 tPPKsPSSAKSRLQT
A239 PPKsPSSAKSRLQTA
S241 KsPSSAKSRLQTAPV
T245 SAKSRLQTAPVPMPD
K254 PVPMPDLKNVKSKIG
K254 PVPMPDLKNVKSKIG
S258 PDLKNVKSKIGsTEN
K259 DLKNVKSKIGsTENL
S262-p NVKSKIGsTENLKHQ
T263 VKSKIGsTENLKHQP
K267 IGsTENLKHQPGGGK
K274 KHQPGGGKVQIVYKP
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
Y279 GGKVQIVYKPVDLsK
K280 GKVQIVYKPVDLsKV
K280 GKVQIVYKPVDLsKV
S285-p VYKPVDLsKVtSKCG
T288-p PVDLsKVtSKCGsLG
S289 VDLsKVtSKCGsLGN
S293-p KVtSKCGsLGNIHHK
K309 GGGQVEVKSEKLDFK
S310 GGQVEVKSEKLDFKD
S321 DFKDRVQSKIGsLDN
K322 FKDRVQSKIGsLDNI
S325-p RVQSKIGsLDNITHV
S325 RVQSKIGSLDNITHV
T330 IGsLDNITHVPGGGN
K338-ac HVPGGGNkkIETHKL
K339-ac VPGGGNkkIETHKLT
T342 GGNkkIETHKLTFRE
T346 kIETHKLTFRENAKA
T355 RENAKAKTDHGAEIV
Y363 DHGAEIVYKsPVVsG
S365-p GAEIVYKsPVVsGDT
S369-p VYKsPVVsGDTsPRH
S369 VYKsPVVSGDTsPRH
T372 sPVVsGDTsPRHLSN
S373-p PVVsGDTsPRHLSNV
S378 DTsPRHLSNVSSTGS
S381 PRHLSNVSSTGSIDM
S382 RHLSNVSSTGSIDMV
T383 HLSNVSSTGSIDMVD
S385 SNVSSTGSIDMVDSP
S391 GSIDMVDSPQLATLA
T396 VDSPQLATLADEVSA
S402 ATLADEVSASLAKQG
S404 LADEVSASLAKQGL_
5383 : Phospho-Tau (Thr181) Antibody
12885 : Phospho-Tau (Thr181) (D9F4G) Rabbit mAb
11834 : Phospho-Tau (Ser202) Antibody
9632 : Phospho-Tau (Ser396) (PHF13) Mouse mAb
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
  Tau iso6  
T17 VMEDHAGTYGLGDRK
Y18 MEDHAGTYGLGDRKD
Y29 DRKDQGGYTMHQDQE
T39 HQDQEGDTDAGLKAE
K44 GDTDAGLKAEEAGIG
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
- gap
T53 EEAGIGDTPSLEDEA
S55 AGIGDTPSLEDEAAG
T65 DEAAGHVTQARMVSK
T65 DEAAGHVTQARMVSK
- gap
- gap
- gap
- gap
- gap
S73 QARMVSKSKDGTGSD
T77 VSKSKDGTGSDDKKA
S79 KSKDGTGSDDKKAKG
- gap
- gap
- gap
T91 AKGADGKTKIATPRG
T95 DGKTKIATPRGAAPP
P101 ATPRGAAPPGQKGQA
K105 GAAPPGQKGQANATR
Q107 APPGQKGQANATRIP
T111 QKGQANATRIPAKTP
K116 NATRIPAKTPPAPKt
T117 ATRIPAKTPPAPKtP
P118 TRIPAKTPPAPKtPP
A120 IPAKTPPAPKtPPSS
K122 AKTPPAPKtPPSSGE
T123-p KTPPAPKtPPSSGEP
S126 PAPKtPPSSGEPPKS
S127 APKtPPSSGEPPKSG
S133 SSGEPPKSGDRSGYS
S137 PPKSGDRSGYSSPGs
Y139 KSGDRSGYSSPGsPG
S140 SGDRSGYSSPGsPGt
S141 GDRSGYSSPGsPGtP
S144-p SGYSSPGsPGtPGSR
T147-p SSPGsPGtPGSRSRt
S150 GsPGtPGSRSRtPsL
S150 GsPGtPGSRSRtPsL
S152 PGtPGSRSRtPsLPT
T154-p tPGSRSRtPsLPTPP
S156-p GSRSRtPsLPTPPTR
T159 SRtPsLPTPPTREPK
T162 PsLPTPPTREPKKVA
T173-p KKVAVVRtPPKsPSS
S177-p VVRtPPKsPSSAKSR
S179 RtPPKsPSSAKSRLQ
S180 tPPKsPSSAKSRLQT
S180 tPPKsPSSAKSRLQT
A181 PPKsPSSAKSRLQTA
S183 KsPSSAKSRLQTAPV
T187 SAKSRLQTAPVPMPD
K196 PVPMPDLKNVKSKIG
K196 PVPMPDLKNVKSKIG
S200 PDLKNVKSKIGsTEN
K201 DLKNVKSKIGsTENL
S204-p NVKSKIGsTENLKHQ
T205 VKSKIGsTENLKHQP
K209 IGsTENLKHQPGGGK
K216 KHQPGGGKVQIINKK
K222 GKVQIINKKLDLSNV
K223 KVQIINKKLDLSNVQ
S227 INKKLDLSNVQSKCG
S231 LDLSNVQSKCGSKDN
K232 DLSNVQSKCGSKDNI
K232 DLSNVQSKCGSKDNI
S235 NVQSKCGSKDNIKHV
S247 KHVPGGGSVQIVYKP
Y252 GGSVQIVYKPVDLsK
K253 GSVQIVYKPVDLsKV
K253 GSVQIVYKPVDLsKV
S258-p VYKPVDLsKVtSKCG
T261-p PVDLsKVtSKCGsLG
S262 VDLsKVtSKCGsLGN
S266-p KVtSKCGsLGNIHHK
K282 GGGQVEVKSEKLDFK
S283 GGQVEVKSEKLDFKD
S294 DFKDRVQSKIGsLDN
K295 FKDRVQSKIGsLDNI
S298-p RVQSKIGsLDNITHV
S298 RVQSKIGSLDNITHV
T303 IGsLDNITHVPGGGN
K311-ac HVPGGGNkkIETHKL
K312-ac VPGGGNkkIETHKLT
T315 GGNkkIETHKLTFRE
T319 kIETHKLTFRENAKA
T328 RENAKAKTDHGAEIV
Y336 DHGAEIVYKsPVVSG
S338-p GAEIVYKsPVVSGDT
S342 VYKsPVVSGDTsPRH
S342 VYKsPVVSGDTsPRH
T345 sPVVSGDTsPRHLSN
S346-p PVVSGDTsPRHLSNV
S351 DTsPRHLSNVSSTGS
S354 PRHLSNVSSTGSIDM
S355 RHLSNVSSTGSIDMV
T356 HLSNVSSTGSIDMVD
S358 SNVSSTGSIDMVDSP
S364 GSIDMVDSPQLATLA
T369 VDSPQLATLADEVSA
S375 ATLADEVSASLAKQG
S377 LADEVSASLAKQGL_
5383 : Phospho-Tau (Thr181) Antibody
12885 : Phospho-Tau (Thr181) (D9F4G) Rabbit mAb
11834 : Phospho-Tau (Ser202) Antibody
9632 : Phospho-Tau (Ser396) (PHF13) Mouse mAb
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
  Tau iso7  
T17 VMEDHAGTYGLGDRK
Y18 MEDHAGTYGLGDRKD
Y29 DRKDQGGYTMHQDQE
T39 HQDQEGDTDAGLKES
K44 GDTDAGLKESPLQTP
S46 TDAGLKESPLQTPTE
T50 LKESPLQTPTEDGSE
T52 ESPLQTPTEDGSEEP
S56 QTPTEDGSEEPGSET
S61 DGSEEPGSETSDAKS
T63 SEEPGSETSDAKSTP
S64 EEPGSETSDAKSTPT
S68 SETSDAKSTPTAEAE
T69 ETSDAKSTPTAEAEE
T71 SDAKSTPTAEAEEAG
- gap
- gap
- gap
T82 EEAGIGDTPsLEDEA
S84-p AGIGDTPsLEDEAAG
T94 DEAAGHVTQARMVSK
T94 DEAAGHVTQARMVSK
- gap
- gap
- gap
- gap
- gap
S102 QARMVSKSKDGTGSD
T106 VSKSKDGTGSDDKKA
S108 KSKDGTGSDDKKAKG
- gap
- gap
- gap
T120 AKGADGKTKIATPRG
T124 DGKTKIATPRGAAPP
P130 ATPRGAAPPGQKGQA
K134 GAAPPGQKGQANATR
Q136 APPGQKGQANATRIP
T140 QKGQANATRIPAKTP
K145 NATRIPAKTPPAPKT
T146 ATRIPAKTPPAPKTP
P147 TRIPAKTPPAPKTPP
A149 IPAKTPPAPKTPPSS
K151 AKTPPAPKTPPSSGE
T152 KTPPAPKTPPSSGEP
S155 PAPKTPPSSGEPPKS
S156 APKTPPSSGEPPKSG
S162 SSGEPPKSGDRSGYS
S166 PPKSGDRSGYSSPGS
Y168 KSGDRSGYSSPGSPG
S169 SGDRSGYSSPGSPGT
S170 GDRSGYSSPGSPGTP
S173 SGYSSPGSPGTPGSR
T176 SSPGSPGTPGSRSRT
S179 GSPGTPGSRSRTPSL
S179 GSPGTPGSRSRTPSL
S181 PGTPGSRSRTPSLPT
T183 TPGSRSRTPSLPTPP
S185 GSRSRTPSLPTPPTR
T188 SRTPSLPTPPTREPK
T191 PSLPTPPTREPKKVA
T202 KKVAVVRTPPKSPSS
S206 VVRTPPKSPSSAKSR
S208 RTPPKSPSSAKSRLQ
S209 TPPKSPSSAKSRLQT
S209 TPPKSPSSAKSRLQT
A210 PPKSPSSAKSRLQTA
S212 KSPSSAKSRLQTAPV
T216 SAKSRLQTAPVPMPD
K225 PVPMPDLKNVKSKIG
K225 PVPMPDLKNVKSKIG
S229 PDLKNVKSKIGSTEN
K230 DLKNVKSKIGSTENL
S233 NVKSKIGSTENLKHQ
T234 VKSKIGSTENLKHQP
K238 IGSTENLKHQPGGGK
K245 KHQPGGGKVQIINKK
K251 GKVQIINKKLDLSNV
K252 KVQIINKKLDLSNVQ
S256 INKKLDLSNVQSKCG
S260 LDLSNVQSKCGSKDN
K261 DLSNVQSKCGSKDNI
K261 DLSNVQSKCGSKDNI
S264 NVQSKCGSKDNIKHV
S276 KHVPGGGSVQIVYKP
Y281 GGSVQIVYKPVDLSK
K282 GSVQIVYKPVDLSKV
K282 GSVQIVYKPVDLSKV
S287 VYKPVDLSKVTSKCG
T290 PVDLSKVTSKCGSLG
S291 VDLSKVTSKCGSLGN
S295 KVTSKCGSLGNIHHK
K311 GGGQVEVKSEKLDFK
S312 GGQVEVKSEKLDFKD
S323 DFKDRVQSKIGSLDN
K324 FKDRVQSKIGSLDNI
S327 RVQSKIGSLDNITHV
S327 RVQSKIGSLDNITHV
T332 IGSLDNITHVPGGGN
K340 HVPGGGNKKIETHKL
K341 VPGGGNKKIETHKLT
T344 GGNKKIETHKLTFRE
T348 KIETHKLTFRENAKA
T357 RENAKAKTDHGAEIV
Y365 DHGAEIVYKSPVVSG
S367 GAEIVYKSPVVSGDT
S371 VYKSPVVSGDTSPRH
S371 VYKSPVVSGDTSPRH
T374 SPVVSGDTSPRHLSN
S375 PVVSGDTSPRHLSNV
S380 DTSPRHLSNVSSTGS
S383 PRHLSNVSSTGSIDM
S384 RHLSNVSSTGSIDMV
T385 HLSNVSSTGSIDMVD
S387 SNVSSTGSIDMVDSP
S393 GSIDMVDSPQLATLA
T398 VDSPQLATLADEVSA
S404 ATLADEVSASLAKQG
S406 LADEVSASLAKQGL_
  Tau iso8  
T17-p VMEDHAGtyGLGDRK
Y18-p MEDHAGtyGLGDRKD
Y29-p DRKDQGGyTMHQDQE
T39-p HQDQEGDtDAGLkEs
K44-m1 GDtDAGLkEsPLQtP
S46-p tDAGLkEsPLQtPtE
T50-p LkEsPLQtPtEDGsE
T52-p EsPLQtPtEDGsEEP
S56-p QtPtEDGsEEPGSET
S61 DGsEEPGSETSDAKs
T63 sEEPGSETSDAKstP
S64 EEPGSETSDAKstPt
S68-p SETSDAKstPtAEDV
T69-p ETSDAKstPtAEDVT
T71-p SDAKstPtAEDVTAP
T95-p QAAAQPHtEIPEGtt
T101-p HtEIPEGttAEEAGI
T102-p tEIPEGttAEEAGIG
T111-p EEAGIGDtPsLEDEA
S113-p AGIGDtPsLEDEAAG
T123-gl DEAAGHVtQARMVSK
T123-p DEAAGHVtQARMVSK
- gap
- gap
- gap
- gap
- gap
S131-p QARMVSKsKDGTGSD
T135 VSKsKDGTGSDDKKA
S137 KsKDGTGSDDKKAKG
- gap
- gap
- gap
T149-p AKGADGKtKIAtPRG
T153-p DGKtKIAtPRGAAPP
P159 AtPRGAAPPGQkGQA
K163-m1 GAAPPGQkGQANAtR
Q165 APPGQkGQANAtRIP
T169-p QkGQANAtRIPAktP
K174-m1 NAtRIPAktPPAPkt
T175-p AtRIPAktPPAPktP
P176 tRIPAktPPAPktPP
A178 IPAktPPAPktPPss
K180-m1 AktPPAPktPPssGE
T181-p ktPPAPktPPssGEP
S184-p PAPktPPssGEPPKs
S185-p APktPPssGEPPKsG
S191-p ssGEPPKsGDRsGys
S195-p PPKsGDRsGyssPGs
Y197-p KsGDRsGyssPGsPG
S198-p sGDRsGyssPGsPGt
S199-p GDRsGyssPGsPGtP
S202-p sGyssPGsPGtPGsR
T205-p ssPGsPGtPGsRsRt
S208-gl GsPGtPGsRsRtPsL
S208-p GsPGtPGsRsRtPsL
S210-p PGtPGsRsRtPsLPt
T212-p tPGsRsRtPsLPtPP
S214-p GsRsRtPsLPtPPtR
T217-p sRtPsLPtPPtREPK
T220-p PsLPtPPtREPKKVA
T231-p KKVAVVRtPPKsPss
S235-p VVRtPPKsPssAKsR
S237-p RtPPKsPssAKsRLQ
S238-gl tPPKsPssAKsRLQt
S238-p tPPKsPssAKsRLQt
A239 PPKsPssAKsRLQtA
S241-p KsPssAKsRLQtAPV
T245-p sAKsRLQtAPVPMPD
K254-m1 PVPMPDLkNVKsKIG
K254-ub PVPMPDLkNVKsKIG
S258-p PDLkNVKsKIGstEN
K259 DLkNVKsKIGstENL
S262-p NVKsKIGstENLkHQ
T263-p VKsKIGstENLkHQP
K267-m1 IGstENLkHQPGGGk
K274-ac kHQPGGGkVQIINkK
K280-ac GkVQIINkKLDLsNV
K281 kVQIINkKLDLsNVQ
S285-p INkKLDLsNVQskCG
S289-p LDLsNVQskCGsKDN
K290-m1 DLsNVQskCGsKDNI
K290 DLsNVQsKCGsKDNI
S293-p NVQskCGsKDNIKHV
S305-p KHVPGGGsVQIVykP
Y310-p GGsVQIVykPVDLsK
K311 GsVQIVyKPVDLsKV
K311-ub GsVQIVykPVDLsKV
S316-p VykPVDLsKVtsKCG
T319-p PVDLsKVtsKCGsLG
S320-p VDLsKVtsKCGsLGN
S324-p KVtsKCGsLGNIHHK
K340-sm GGGQVEVksEKLDFK
S341-p GGQVEVksEKLDFKD
S352-p DFKDRVQskIGsLDN
K353-ub FKDRVQskIGsLDNI
S356-p RVQskIGsLDNItHV
S356-gl RVQskIGsLDNItHV
T361-p IGsLDNItHVPGGGN
K369-ac HVPGGGNkkIEtHKL
K370-ac VPGGGNkkIEtHKLt
T373-p GGNkkIEtHKLtFRE
T377-p kIEtHKLtFRENAKA
T386-p RENAKAKtDHGAEIV
Y394-p DHGAEIVyKsPVVsG
S396-p GAEIVyKsPVVsGDt
S400-p VyKsPVVsGDtsPRH
S400-gl VyKsPVVsGDtsPRH
T403-p sPVVsGDtsPRHLsN
S404-p PVVsGDtsPRHLsNV
S409-p DtsPRHLsNVsstGs
S412-p PRHLsNVsstGsIDM
S413-p RHLsNVsstGsIDMV
T414-p HLsNVsstGsIDMVD
S416-p sNVsstGsIDMVDsP
S422-p GsIDMVDsPQLAtLA
T427-p VDsPQLAtLADEVsA
S433-p AtLADEVsAsLAKQG
S435-p LADEVsAsLAKQGL_
5383 : Phospho-Tau (Thr181) Antibody
12885 : Phospho-Tau (Thr181) (D9F4G) Rabbit mAb
11834 : Phospho-Tau (Ser202) Antibody
9632 : Phospho-Tau (Ser396) (PHF13) Mouse mAb
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
  mouse

► Hide Isoforms
 
- gap
- gap
Y18 MEDHAGDYTLLQDQE
M28 LQDQEGDMDHGLKEs
K33 GDMDHGLKEsPPQPP
S35-p MDHGLKEsPPQPPAD
P39 LKEsPPQPPADDGAE
A41 EsPPQPPADDGAEEP
A45 QPPADDGAEEPGsEt
S50-p DGAEEPGsEtsDAKs
T52-p AEEPGsEtsDAKstP
S53-p EEPGsEtsDAKstPt
S57-p sEtsDAKstPtAEDV
T58-p EtsDAKstPtAEDVT
T60-p sDAKstPtAEDVTAP
T84 QAAAQPHTEIPEGIT
I90 HTEIPEGITAEEAGI
T91 TEIPEGITAEEAGIG
T100-p EEAGIGDtPNQEDQA
N102 AGIGDtPNQEDQAAG
T112 DQAAGHVTQGRREGQ
T112 DQAAGHVTQGRREGQ
S154 REATCQPSGTRPEDI
T156 ATCQPSGTRPEDIEK
S188-p WGQDRLGsEEEVDED
S208-p SSQDSPPsQASLTPG
S211 DSPPsQASLTPGRAA
S355 QLKARVASKDRTGND
T359 RVASKDRTGNDEKKA
N361 ASKDRTGNDEKKAKT
S384 PSHRPCLSPTRPTLG
N422 VSSVTPRNGSPGTKQ
S424 SVTPRNGSPGTKQMK
T439 LKGADGKTGAKIATP
T445 KTGAKIATPRGAAsP
S451-p ATPRGAAsPAQKGtS
K455 GAAsPAQKGtSNATR
T457-p AsPAQKGtSNATRIP
T461 QKGtSNATRIPAKtt
K466 NATRIPAKttPsPKt
T467-p ATRIPAKttPsPKtP
T468-p TRIPAKttPsPKtPP
S470-p IPAKttPsPKtPPGs
K472 AKttPsPKtPPGsGE
T473-p KttPsPKtPPGsGEP
G476 PsPKtPPGsGEPPKs
S477-p sPKtPPGsGEPPKsG
S483-p GsGEPPKsGERsGys
S487-p PPKsGERsGyssPGs
Y489-p KsGERsGyssPGsPG
S490-p sGERsGyssPGsPGt
S491-p GERsGyssPGsPGtP
S494-p sGyssPGsPGtPGsR
T497-p ssPGsPGtPGsRsRt
S500 GsPGtPGSRsRtPsL
S500-p GsPGtPGsRsRtPsL
S502-p PGtPGsRsRtPsLPt
T504-p tPGsRsRtPsLPtPP
S506-p GsRsRtPsLPtPPtR
T509-p sRtPsLPtPPtREPK
T512-p PsLPtPPtREPKKVA
T523-p KKVAVVRtPPKsPsA
S527-p VVRtPPKsPsAsKSR
S529-p RtPPKsPsAsKSRLQ
A530 tPPKsPsAsKSRLQT
A530 tPPKsPsAsKSRLQT
S531-p PPKsPsAsKSRLQTA
S533 KsPsAsKSRLQTAPV
T537 AsKSRLQTAPVPMPD
K546 PVPMPDLKNVRSkIG
K546-ub PVPMPDLkNVRSkIG
S550 PDLkNVRSkIGstEN
K551-m1 DLkNVRSkIGstENL
S554-p NVRSkIGstENLKHQ
T555-p VRSkIGstENLKHQP
K559 IGstENLKHQPGGGK
K566 KHQPGGGKVQIINKk
K572 GKVQIINKkLDLSNV
K573-ub KVQIINKkLDLSNVQ
S577 INKkLDLSNVQskCG
S581-p LDLSNVQskCGSKDN
K582 DLSNVQsKCGSKDNI
K582-ub DLSNVQskCGSKDNI
S585 NVQskCGSKDNIKHV
S597 KHVPGGGSVQIVykP
Y602-p GGSVQIVykPVDLSK
K603 GSVQIVyKPVDLSKV
K603-ub GSVQIVykPVDLSKV
S608 VykPVDLSKVTSKCG
T611 PVDLSKVTSKCGSLG
S612 VDLSKVTSKCGSLGN
S616 KVTSKCGSLGNIHHK
K632 GGGQVEVKSEKLDFK
S633 GGQVEVKSEKLDFKD
S644 DFKDRVQSKIGsLDN
K645 FKDRVQSKIGsLDNI
S648-p RVQSKIGsLDNITHV
S648 RVQSKIGSLDNITHV
T653 IGsLDNITHVPGGGN
K661-ac HVPGGGNkKIETHKL
K662 VPGGGNkKIETHKLt
T665 GGNkKIETHKLtFRE
T669-p KIETHKLtFRENAKA
T678 RENAKAKTDHGAEIV
Y686-p DHGAEIVyKsPVVsG
S688-p GAEIVyKsPVVsGDt
S692-p VyKsPVVsGDtsPRH
S692-gl VyKsPVVsGDtsPRH
T695-p sPVVsGDtsPRHLsN
S696-p PVVsGDtsPRHLsNV
S701-p DtsPRHLsNVsstGs
S704-p PRHLsNVsstGsIDM
S705-p RHLsNVsstGsIDMV
T706-p HLsNVsstGsIDMVD
S708-p sNVsstGsIDMVDsP
S714-p GsIDMVDsPQLAtLA
T719-p VDsPQLAtLADEVSA
S725 AtLADEVSASLAKQG
S727 LADEVSASLAKQGL_
5383 : Phospho-Tau (Thr181) Antibody
12885 : Phospho-Tau (Thr181) (D9F4G) Rabbit mAb
11834 : Phospho-Tau (Ser202) Antibody
9632 : Phospho-Tau (Ser396) (PHF13) Mouse mAb
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
11837 : Phospho-Tau (Ser400/Thr403/Ser404) Antibody
  Tau iso3  
- gap
- gap
Y18 MEDHAGDYTLLQDQE
M28 LQDQEGDMDHGLKES
K33 GDMDHGLKESPPQPP
S35 MDHGLKESPPQPPAD
P39 LKESPPQPPADDGAE
A41 ESPPQPPADDGAEEP
A45 QPPADDGAEEPGSET
S50 DGAEEPGSETSDAKS
T52 AEEPGSETSDAKSTP
S53 EEPGSETSDAKSTPT
S57 SETSDAKSTPTAEDV
T58 ETSDAKSTPTAEDVT
T60 SDAKSTPTAEDVTAP
T84 QAAAQPHTEIPEGIT
I90 HTEIPEGITAEEAGI
T91 TEIPEGITAEEAGIG
T100-p EEAGIGDtPNQEDQA
N102 AGIGDtPNQEDQAAG
T112 DQAAGHVTQARVASK
T112 DQAAGHVTQARVASK
- gap
- gap
- gap
- gap
- gap
S118 VTQARVASKDRTGND
T122 RVASKDRTGNDEKKA
N124 ASKDRTGNDEKKAKG
- gap
- gap
- gap
T136 AKGADGKTGAKIATP
T142 KTGAKIATPRGAASP
S148 ATPRGAASPAQKGTS
K152 GAASPAQKGTSNATR
T154 ASPAQKGTSNATRIP
T158 QKGTSNATRIPAKTT
K163 NATRIPAKTTPSPKT
T164 ATRIPAKTTPSPKTP
T165 TRIPAKTTPSPKTPP
S167 IPAKTTPSPKTPPGS
K169 AKTTPSPKTPPGSGE
T170 KTTPSPKTPPGSGEP
G173 PSPKTPPGSGEPPKS
S174 SPKTPPGSGEPPKSG
S180 GSGEPPKSGERSGYS
S184 PPKSGERSGYSSPGS
Y186 KSGERSGYSSPGSPG
S187 SGERSGYSSPGSPGT
S188 GERSGYSSPGSPGTP
S191 SGYSSPGSPGTPGSR
T194 SSPGSPGTPGSRSRT
S197 GSPGTPGSRSRTPSL
S197 GSPGTPGSRSRTPSL
S199 PGTPGSRSRTPSLPT
T201 TPGSRSRTPSLPTPP
S203 GSRSRTPSLPTPPTR
T206 SRTPSLPTPPTREPK
T209 PSLPTPPTREPKKVA
T220 KKVAVVRTPPKSPSA
S224 VVRTPPKSPSASKSR
S226 RTPPKSPSASKSRLQ
A227 TPPKSPSASKSRLQT
A227 TPPKSPSASKSRLQT
S228 PPKSPSASKSRLQTA
S230 KSPSASKSRLQTAPV
T234 ASKSRLQTAPVPMPD
K243 PVPMPDLKNVRSKIG
K243 PVPMPDLKNVRSKIG
S247 PDLKNVRSKIGSTEN
K248 DLKNVRSKIGSTENL
S251 NVRSKIGSTENLKHQ
T252 VRSKIGSTENLKHQP
K256 IGSTENLKHQPGGGK
K263 KHQPGGGKVQIINKK
K269 GKVQIINKKLDLSNV
K270 KVQIINKKLDLSNVQ
S274 INKKLDLSNVQSKCG
S278 LDLSNVQSKCGSKDN
K279 DLSNVQSKCGSKDNI
K279 DLSNVQSKCGSKDNI
S282 NVQSKCGSKDNIKHV
S294 KHVPGGGSVQIVYKP
Y299 GGSVQIVYKPVDLSK
K300 GSVQIVYKPVDLSKV
K300 GSVQIVYKPVDLSKV
S305 VYKPVDLSKVTSKCG
T308 PVDLSKVTSKCGSLG
S309 VDLSKVTSKCGSLGN
S313 KVTSKCGSLGNIHHK
K329 GGGQVEVKSEKLDFK
S330 GGQVEVKSEKLDFKD
S341 DFKDRVQSKIGSLDN
K342 FKDRVQSKIGSLDNI
S345 RVQSKIGSLDNITHV
S345 RVQSKIGSLDNITHV
T350 IGSLDNITHVPGGGN
K358 HVPGGGNKKIETHKL
K359 VPGGGNKKIETHKLT
T362 GGNKKIETHKLTFRE
T366 KIETHKLTFRENAKA
T375 RENAKAKTDHGAEIV
Y383 DHGAEIVYKSPVVSG
S385 GAEIVYKSPVVSGDT
S389 VYKSPVVSGDTSPRH
S389 VYKSPVVSGDTSPRH
T392 SPVVSGDTSPRHLSN
S393 PVVSGDTSPRHLSNV
S398 DTSPRHLSNVSSTGS
S401 PRHLSNVSSTGSIDM
S402 RHLSNVSSTGSIDMV
T403 HLSNVSSTGSIDMVD
S405 SNVSSTGSIDMVDSP
S411 GSIDMVDSPQLATLA
T416 VDSPQLATLADEVSA
S422 ATLADEVSASLAKQG
S424 LADEVSASLAKQGL_