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Protein Page:
PDCD1LG2 (human)

Overview
PDCD1LG2 Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Receptor, misc.; Membrane protein, integral
Cellular Component: plasma membrane; integral to membrane; extracellular region; endomembrane system
Molecular Function: molecular_function
Biological Process: negative regulation of T cell proliferation; T cell costimulation; immune response; positive regulation of T cell proliferation
Reference #:  Q9BQ51 (UniProtKB)
Alt. Names/Synonyms: B7-DC; B7DC; bA574F11.2; Btdc; Butyrophilin B7-DC; CD273; MGC142238; MGC142240; PD-1 ligand 2; PD-1-ligand 2; PD-L2; PD1L2; PDCD1 ligand 2; PDCD1L2; PDCD1LG2; PDL2; Programmed cell death 1 ligand 2; Programmed death ligand 2
Gene Symbols: PDCD1LG2
Molecular weight: 30,957 Da
Basal Isoelectric point: 8.18  Predict pI for various phosphorylation states
Select Structure to View Below

PDCD1LG2

Protein Structure Not Found.


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