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Protein Page:
KIFC1 (human)
p Phosphorylation
a Acetylation
m Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
u Ubiquitination
s Sumoylation
n Neddylation
gl O-GlcNAc
ga O-GalNAc
h Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage

Overview
KIFC1 Minus end-directed microtubule-dependent motor required for bipolar spindle formation. May contribute to movement of early endocytic vesicles. Belongs to the kinesin-like protein family. NCD subfamily. Binds NUBP1 and NUBP2. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; Motor protein; Microtubule binding protein
Cellular Component: microtubule; microtubule associated complex; early endosome; microtubule organizing center; spindle; nucleus
Molecular Function: microtubule motor activity; ATP binding
Biological Process: mitotic sister chromatid segregation; cell division; blood coagulation; microtubule-based movement
Reference #:  Q9BW19 (UniProtKB)
Alt. Names/Synonyms: HSET; KIFC1; kinesin family member C1; kinesin-like 2; Kinesin-like protein 2; Kinesin-like protein KIFC1; Kinesin-related protein HSET; KNSL2; MGC1202; MGC149736; MGC149737
Gene Symbols: KIFC1
Molecular weight: 73,748 Da
Basal Isoelectric point: 9.15  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

KIFC1
Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


  MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


        human

 
0 4 S6-p __MDPQRsPLLEVKG
0 17 S26-p RPLIKAPsQLPLsGS
0 2 S31-p APsQLPLsGSRLKRR
0 1 S33 sQLPLsGSRLKRRPD
0 1 K61-a RGLGATTkITTSHPR
0 1 T64 GATTkITTSHPRVPS
0 2 T101 RCSTAIATGLKNQkP
0 1 K107-a ATGLKNQkPVPAVPV
0 3 K107-u ATGLKNQkPVPAVPV
0 1 K308-u HNQLQELkGNIRVFC
0 1 S353 TRLSLSRSDERRGtL
0 2 G358 SRSDERRGtLsGAPA
0 14 T359-p RSDERRGtLsGAPAP
0 1 S361-p DERRGtLsGAPAPPT
0 3 K479-u LLATGTRkGQGGECE
0 2 G491 ECEIRRAGPGsEELT
0 1 S494-p IRRAGPGsEELTVTN
0 1 K511-u YVPVSCEkEVDALLH
0 1 K619-u HVPYRNSkLTyLLQN
0 1 Y622-p YRNSkLTyLLQNSLG
  mouse

 
P8 MDVQAQRPPLLEVKR
S28 AALVKSSSRVPLSAs
S33 SSSRVPLSAsRLKRG
S35-p SRVPLSAsRLKRGPD
K63 RVMGAVTKVDtSRPR
T66-p GAVTKVDtSRPRGPL
T103-p RGCSAIGtVLRSQKP
K109 GtVLRSQKPVPAAPA
K109 GtVLRSQKPVPAAPA
K309 HNQLQELKGNIRVFC
S354-p TGLSLSRsDDRRstL
S359-p SRsDDRRstLTGAPA
T360-p RsDDRRstLTGAPAP
T362 DDRRstLTGAPAPTV
K480-u LLATGPRkGQGGECE
S492-p ECEIRRAsPGSEELT
S495 IRRAsPGSEELTVTN
K512 YVPVSCEKEVEALLH
K620 HVPYRNSKLTYLLQN
Y623 YRNSKLTYLLQNSLG
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