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NDUFA8 (human)

Overview NDUFA8 Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA8 subunit family. Note: This description may include information from UniProtKB. Protein type: EC 1.6.5.3; Energy Metabolism - oxidative phosphorylation; EC 1.6.99.3; Oxidoreductase; Mitochondrial Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial respiratory chain complex I Molecular Function: NADH dehydrogenase (ubiquinone) activity Biological Process: mitochondrial electron transport, NADH to ubiquinone Reference #:  P51970 (UniProtKB) Alt. Names/Synonyms: CI-19kD; CI-PGIV; Complex I-19kD; Complex I-PGIV; MGC793; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; NADH-ubiquinone oxidoreductase 19 kDa subunit; NADH:ubiquinone oxidoreductase PGIV subunit; NDUA8; NDUFA8; PGIV Gene Symbols: NDUFA8 Molecular weight: 20,105 Da Basal Isoelectric point: 7.58  Predict pI for various phosphorylation states

Select Structure to View Below NDUFA8

STRING  |  Scansite  |  Phospho.ELM  |  NetworKIN  |  Pfam  |  ENZYME 1.6.5.3 1.6.99.3  |  DISEASE  |  Source  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene

	Modification Sites and Domains	Show Modification Legend
Click here to view phosphorylation modifications only

	Modification Sites in Parent Protein, Orthologs, and Isoforms	Show Modification Legend

SS  SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.	MS  MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.			human
0	5		K14-u	LPTLEELkVDEVkIS
0	4		K19-u	ELkVDEVkISSAVLK
0	2		K38-u	HYGAQCDkPNKEFML
0	3		K61-u	RRCLEEGkLVNkCAL
0	4		K65-u	EEGkLVNkCALDFFR
0	17		K102-u	QLFRHCRkQQAkFDE
0	100		K106-u	HCRkQQAkFDECVLD
0	1		K127-u	PDLGELSkVTKVKTD
0	34		Y142-p	RPLPENPyHSRPRPD
0	3		S151-p	SRPRPDPsPEIEGDL
0	1		Y168-p	ATHGSRFyFWTK___

	mouse
K14	LPTLEELKVEEVKVS
K19	ELKVEEVKVSSAVLK
K38	HYGAQCDKTNKEFML
K61	RRCLKEGKLVNGCAL
G65	KEGKLVNGCALNFFR
Q102	QLFRHCRQQQAkFDQ
K106-u	HCRQQQAkFDQCVLD
K127	PDLGQLSKVTKVKTD
Y142-p	RPLPENPyHSRARPE
N151	SRARPEPNPVIEGDL
F168	AKHGTRFFFWTV___

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