a phosphatidylinositol-specific phospholipase C. Binds to calmodulin. The activated enzyme produces the second messenger molecules diacylglycerol and inositol 1,4,5-trisphosphate. Note: This description may include information from UniProtKB.
Protein type: Phospholipase; Carbohydrate Metabolism - inositol phosphate; EC 220.127.116.11
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: nucleoplasm; protein complex; membrane; cytosol
Molecular Function: calmodulin binding; signal transducer activity; calcium ion binding; phosphoinositide phospholipase C activity; phospholipase C activity
Biological Process: synaptic transmission; inositol phosphate metabolic process; regulation of systemic arterial blood pressure; lipid catabolic process
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.