Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rab family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: G protein, monomeric; G protein; G protein, monomeric, Rab
Chromosomal Location of Human Ortholog: 2p14
Cellular Component: Golgi membrane; endoplasmic reticulum; early endosome; melanosome; cytosol
Molecular Function: GTPase activity; protein binding; GTP binding
Biological Process: vesicle-mediated transport; growth hormone secretion; cell migration; ER to Golgi vesicle-mediated transport; GTP catabolic process; small GTPase mediated signal transduction; defense response to bacterium; vesicle transport along microtubule; autophagy; endocytosis; mitotic cell cycle; autophagic vacuole formation
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.