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Protein Page:
Rab1A (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitination
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
Rab1A Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rab family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: G protein, monomeric; G protein; G protein, monomeric, Rab
Chromosomal Location of Human Ortholog: 2p14
Cellular Component: Golgi membrane; endoplasmic reticulum; early endosome; melanosome; cytosol
Molecular Function: GTPase activity; protein binding; GTP binding
Biological Process: vesicle-mediated transport; growth hormone secretion; cell migration; ER to Golgi vesicle-mediated transport; GTP catabolic process; small GTPase mediated signal transduction; defense response to bacterium; vesicle transport along microtubule; autophagy; endocytosis; mitotic cell cycle; autophagic vacuole formation
Reference #:  P62820 (UniProtKB)
Alt. Names/Synonyms: DKFZp564B163; GTP binding protein Rab1a; Rab GTPase YPT1 homolog; RAB1; RAB1, member RAS oncogene family; RAB1A; RAB1A, member RAS oncogene family; Ras-related protein Rab-1A; YPT1; YPT1-related protein
Gene Symbols: RAB1A
Molecular weight: 22,678 Da
Basal Isoelectric point: 5.93  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

Rab1A

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 SS 

SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 MS 

MS: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 6 Y8-p MSSMNPEyDyLFKLL
0 4 Y10-p SMNPEyDyLFKLLLI
0 2 S20-p KLLLIGDsGVGKSCL
0 2 Y40-p DDTYTESyISTIGVD
0 1 K61-ac ELDGKTIkLQIWDTA
0 2 K61 ELDGKTIKLQIWDTA
0 24 T75-p AGQERFRtItSSYYR
0 1 T77-p QERFRtItSSYYRGA
0 1 T94-p IIVVYDVtDQESFNN
0 11 K103-ub QESFNNVkQWLQEID
0 6 S114-p QEIDRYAsENVNkLL
0 70 K119-ub YAsENVNkLLVGNKC
0 1 K125 NkLLVGNKCDLTTKK
0 1 K131 NKCDLTTKKVVDyTT
0 4 Y136-p TTKKVVDyTTAKEFA
0 1 T181-p KRMGPGAtAGGAEks
0 10 K187-ub AtAGGAEksNVkIQS
0 1 S188-p tAGGAEksNVkIQSt
0 13 K191-ub GAEksNVkIQStPVK
0 2 T195-p sNVkIQStPVKQSGG
  mouse

 
Y8-p MSSMNPEyDyLFKLL
Y10-p SMNPEyDyLFKLLLI
S20-p KLLLIGDsGVGKSCL
Y40-p DDTYTESyISTIGVD
K61 ELDGKTIKLQIWDTA
K61-ub ELDGKTIkLQIWDTA
T75-p AGQERFRtItSSYYR
T77-p QERFRtItSSYYRGA
T94 IIVVYDVTDQESFNN
K103-ub QESFNNVkQWLQEID
S114-p QEIDRYAsENVNkLL
K119-ub YAsENVNkLLVGNkC
K125-ub NkLLVGNkCDLTTkK
K131-ub NkCDLTTkKVVDYTT
Y136 TTkKVVDYTTAKEFA
T181 KRMGPGATAGGAEkS
K187-ub ATAGGAEkSNVkIQS
S188 TAGGAEkSNVkIQSt
K191-ub GAEkSNVkIQStPVK
T195-p SNVkIQStPVKQSGG
  rat

 
Y8 MSSMNPEYDyLFKLL
Y10-p SMNPEYDyLFKLLLI
S20 KLLLIGDSGVGKSCL
Y40 DDTYTESYISTIGVD
K61-ac ELDGKTIkLQIWDTA
K61-ub ELDGKTIkLQIWDTA
T75 AGQERFRTITSSYYR
T77 QERFRTITSSYYRGA
T94 IIVVYDVTDQESFNN
K103 QESFNNVKQWLQEID
S114 QEIDRYASENVNKLL
K119 YASENVNKLLVGNKC
K125 NKLLVGNKCDLTTKK
K131 NKCDLTTKKVVDyTT
Y136-p TTKKVVDyTTAKEFA
T181 KRMGPGATAGGAEKS
K187 ATAGGAEKSNVKIQS
S188 TAGGAEKSNVKIQST
K191 GAEKSNVKIQSTPVK
T195 SNVKIQSTPVKQSGG
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