a member of the ERM family which includes radixin and moesin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Plays a key role in cell surface structure adhesion, migration, and organization. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal protein; Motility/polarity/chemotaxis
Cellular Component: filopodium membrane; internal side of plasma membrane; focal adhesion; cell surface; microvillus; secretory granule membrane; basolateral plasma membrane; extrinsic to membrane; cytoskeleton; microvillus membrane; apical part of cell; apical plasma membrane; cytoplasm; plasma membrane; nucleolus; uropod; nucleus; filopodium
Molecular Function: protein binding; structural constituent of cytoskeleton; cell adhesion molecule binding; actin binding; protein kinase binding; receptor binding
SS: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.