is an enzyme that functions in DNA replication and the base excision repair process. Mutations leading to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Note: This description may include information from UniProtKB.
Protein type: DNA repair, damage; EC 22.214.171.124; Ligase
Molecular Function: DNA ligase (ATP) activity; DNA ligase activity
Biological Process: anatomical structure morphogenesis; base-excision repair; DNA ligation during DNA repair; DNA metabolic process; DNA repair; mismatch repair; nucleotide-excision repair, DNA gap filling; telomere maintenance via recombination; transcription-coupled nucleotide-excision repair; V(D)J recombination