a transcription factor containing C2H2 zinc fingers. May modulate the functions ascribed to BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. Interacts with CTBP, with the C-terminal (BRCT) domains of BRCA1, and with the retinoblastoma protein. Abundantly expressed in brain and the immune system and associated with immune system malignancies. Ionizing radiation induces its hyperphosphorylation and dissociation from BRCA1 in an ATM-dependent manner. Note: This description may include information from UniProtKB.
Protein type: Transcription, coactivator/corepressor; EC 3.1.-.-
Alt. Names/Synonyms: CtBP-interacting protein; CTIP; RBBP-8; RBBP8; retinoblastoma binding protein 8; Retinoblastoma-binding protein 8; retinoblastoma-interacting myosin-like; Retinoblastoma-interacting protein and myosin-like; RIM
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.