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PhosphoSitePlus
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Protein Page:
ADH1B (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
ADH1B Dimer of identical or non-identical chains of three types; alpha, beta and gamma. Belongs to the zinc-containing alcohol dehydrogenase family. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - metabolism by cytochrome P450; Lipid Metabolism - fatty acid; EC 1.1.1.1; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - retinol; Amino Acid Metabolism - tyrosine; Oxidoreductase
Chromosomal Location of Human Ortholog: 4q23
Cellular Component: cytosol
Molecular Function: alcohol dehydrogenase activity, zinc-dependent; zinc ion binding
Biological Process: ethanol oxidation
Disease: Alcohol Dependence
Reference #:  P00325 (UniProtKB)
Gene Symbols: ADH1B
Molecular weight: 39,855 Da
Basal Isoelectric point: 8.63  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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ADH1B

Protein Structure Not Found.
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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 6 S23‑p WEVKKPFsIEDVEVA
0 338 Y35‑p EVAPPKAyEVRIKMV
0 1 K100‑ac LFTPQCGkCRVCKNP
0 30 Y111‑p CKNPESNyCLKNDLG
0 194 Y150‑p GTSTFSQytVVDENA
0 2 T151‑p TSTFSQytVVDENAV
0 1 K213‑ac LSAVMGCkAAGAARI
0 3 Y320‑p RTWKGAVyGGFKSKE
0 1 K331‑ac KSKEGIPkLVADFMA
0 11 K339‑ac LVADFMAkKFSLDAL
0 2 K367‑ac FDLLHSGkSIRTVLT
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