Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. Note: This description may include information from UniProtKB.
Protein type: Secreted, signal peptide; Oncoprotein; Apoptosis; Cytokine; Secreted; Cell cycle regulation
Biological Process: activation of JAK protein; cytokine and chemokine mediated signaling pathway; hemopoiesis; monocyte differentiation; myeloid cell apoptosis; negative regulation of apoptosis; negative regulation of autophagy; negative regulation of mast cell apoptosis; positive regulation of cell proliferation; positive regulation of JNK cascade; positive regulation of myeloid leukocyte differentiation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein amino acid phosphorylation; regulation of cell growth; regulation of gene expression; regulation of glycolysis; regulation of protein amino acid dephosphorylation; response to hormone stimulus; response to hypoxia