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Protein Page:
NXF1 (human)

NXF1 Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5. Belongs to the NXF family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 11q12.3
Cellular Component: cytosol; nuclear speck; nucleoplasm; nucleus
Molecular Function: protein binding; RNA binding; single-stranded RNA binding
Biological Process: mRNA export from nucleus; poly(A)+ mRNA export from nucleus; RNA export from nucleus
Reference #:  Q9UBU9 (UniProtKB)
Alt. Names/Synonyms: DKFZp667O0311; MEX67; mRNA export factor TAP; Nuclear RNA export factor 1; NXF1; TAP; tip associating protein; Tip-associated protein; Tip-associating protein
Gene Symbols: NXF1
Molecular weight: 70,182 Da
Basal Isoelectric point: 8.74  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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