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Protein Page:
EEA1 (human)

Overview
EEA1 Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding. Interacts with ERBB2. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; Vesicle
Chromosomal Location of Human Ortholog: 12q22
Cellular Component: cytoplasm; cytosol; early endosome; extrinsic to plasma membrane; membrane
Molecular Function: GTP-dependent protein binding; phosphatidylinositol binding; protein binding; protein homodimerization activity; zinc ion binding
Biological Process: endocytosis; synaptic vesicle to endosome fusion; vesicle fusion
Reference #:  Q15075 (UniProtKB)
Alt. Names/Synonyms: Early endosome antigen 1; early endosome antigen 1, 162kD; early endosome-associated protein; EEA1; Endosome-associated protein p162; MST105; MSTP105; ZFYVE2; Zinc finger FYVE domain-containing protein 2
Gene Symbols: EEA1
Molecular weight: 162,466 Da
Basal Isoelectric point: 5.55  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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EEA1

Protein Structure Not Found.
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