Seems to promote the survival of visceral and proprioceptive sensory neurons. Belongs to the NGF-beta family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Secreted, signal peptide; Secreted; Cytokine
Biological Process: activation of MAPK activity; activation of protein kinase B; cell-cell signaling; induction of positive chemotaxis; myelination; negative regulation of neuron apoptosis; negative regulation of peptidyl-tyrosine phosphorylation; nervous system development; neurite morphogenesis; positive chemotaxis; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of glial cell differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of receptor internalization; regulation of apoptosis; regulation of neuron differentiation; regulation of synaptic transmission; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.