a tyrosine kinase of the Tec family. Activity is required for IL6-induced differentiation. May play a role in the growth and differentiation of hematopoietic cells. May be involved in signal transduction in endocardial and arterial endothelial cells. Note: This description may include information from UniProtKB.
Protein type: EC 188.8.131.52; Kinase, protein; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); TK group; Tec family
Cellular Component: cytosol; extrinsic to internal side of plasma membrane; nucleoplasm; plasma membrane
Molecular Function: non-membrane spanning protein tyrosine kinase activity; protein binding; protein-tyrosine kinase activity; receptor binding; signal transducer activity
Biological Process: innate immune response; mesoderm development; NK T cell differentiation; phosphatidylinositol biosynthetic process; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of cell proliferation; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway