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Protein Page:
SLC1A4 (human)

Overview
SLC1A4 Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence. Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A4 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 2p15-p13
Cellular Component: cell surface; centrosome; integral to plasma membrane; intermediate filament; membrane; microtubule organizing center; plasma membrane
Molecular Function: amino acid transmembrane transporter activity; chloride channel activity; L-alanine transmembrane transporter activity; L-cystine transmembrane transporter activity; L-glutamine transmembrane transporter activity; L-proline transmembrane transporter activity; L-serine transmembrane transporter activity; L-threonine transmembrane transporter activity
Biological Process: amino acid transport; cognition; glutamine transport; L-alanine transport; L-cystine transport; L-serine transport; proline transport; threonine transport
Disease: Spastic Tetraplegia, Thin Corpus Callosum, And Progressive Microcephaly
Reference #:  P43007 (UniProtKB)
Alt. Names/Synonyms: Alanine/serine/cysteine/threonine transporter 1; ASCT-1; ASCT1; glutamate/neutral amino acid transporter; Neutral amino acid transporter A; SATT; SLC1A4; solute carrier family 1 (glutamate/neutral amino acid transporter), member 4; Solute carrier family 1 member 4
Gene Symbols: SLC1A4
Molecular weight: 55,723 Da
Basal Isoelectric point: 5.88  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

SLC1A4

Protein Structure Not Found.


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