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Protein Page:
CdGAP (human)

Overview
CdGAP Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration. Interacts with ITSN1, which inhibits GAP activity. Interacts with PARVA. Interacts with GTP-loaded RHOU. Note: This description may include information from UniProtKB.
Protein type: GAPs; GAPs, Rac/Rho
Chromosomal Location of Human Ortholog: 3q13.33
Cellular Component: cytosol
Molecular Function: GTPase activator activity
Biological Process: regulation of small GTPase mediated signal transduction
Disease: Adams-oliver Syndrome 1
Reference #:  Q2M1Z3 (UniProtKB)
Alt. Names/Synonyms: ARHGAP31; Cdc42 GTPase-activating protein; CDGAP; KIAA1204; MGC138368; MGC138370; RHG31; Rho GTPase activating protein 31; Rho GTPase-activating protein 31
Gene Symbols: ARHGAP31
Molecular weight: 156,985 Da
Basal Isoelectric point: 5.55  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

CdGAP

Protein Structure Not Found.


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