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Protein Page:
UGT1A5 (human)

UGT1A5 UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family. 1 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - ascorbate and aldarate; Carbohydrate Metabolism - pentose and glucuronate interconversions; Carbohydrate Metabolism - starch and sucrose; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Cofactor and Vitamin Metabolism - retinol; EC; Lipid Metabolism - androgen and estrogen; Membrane protein, integral; Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - drug metabolism - other enzymes; Xenobiotic Metabolism - metabolism by cytochrome P450
Chromosomal Location of Human Ortholog: 2q37
Cellular Component: intracellular membrane-bound organelle
Molecular Function: glucuronosyltransferase activity
Biological Process: flavonoid biosynthetic process
Reference #:  P35504 (UniProtKB)
Alt. Names/Synonyms: GNT1; UD15; UDP glucuronosyltransferase 1 family, polypeptide A5; UDP glycosyltransferase 1 family, polypeptide A5; UDP-glucuronosyltransferase 1 family polypeptide A5s; UDP-glucuronosyltransferase 1-5; UDP-glucuronosyltransferase 1-E; UDP-glucuronosyltransferase 1A5; UDPGT; UDPGT 1-5; UGT-1E; UGT1; UGT1*5; UGT1-05; UGT1.5; UGT1A5; UGT1E
Gene Symbols: UGT1A5
Molecular weight: 60,071 Da
Basal Isoelectric point: 8.24  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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