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Protein Page:
UGT1A5 (human)
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
UGT1A5 UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family. 1 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Lipid Metabolism - androgen and estrogen; Transferase; EC 2.4.1.17; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - ascorbate and aldarate; Xenobiotic Metabolism - metabolism by cytochrome P450; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Carbohydrate Metabolism - pentose and glucuronate interconversions; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - other enzymes; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q37
Cellular Component: intracellular membrane-bound organelle
Molecular Function: glucuronosyltransferase activity
Biological Process: flavonoid biosynthetic process
Reference #:  P35504 (UniProtKB)
Alt. Names/Synonyms: GNT1; UD15; UDP glucuronosyltransferase 1 family, polypeptide A5; UDP glycosyltransferase 1 family, polypeptide A5; UDP-glucuronosyltransferase 1 family polypeptide A5s; UDP-glucuronosyltransferase 1-5; UDP-glucuronosyltransferase 1-E; UDP-glucuronosyltransferase 1A5; UDPGT; UDPGT 1-5; UGT-1E; UGT1; UGT1*5; UGT1-05; UGT1.5; UGT1A5; UGT1E
Gene Symbols: UGT1A5
Molecular weight: 60,071 Da
Basal Isoelectric point: 8.24  Predict pI for various phosphorylation states
Select Structure to View Below

UGT1A5

Protein Structure Not Found.


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Modification Sites and Domains Show Modification Legend
Click here to view phosphorylation modifications only

Modification Sites in Parent Protein, Orthologs, and Isoforms Show Modification Legend
 

Show Multiple Sequence Alignment



 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 K438‑ac VINDKSYkENIMRLS
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